Yoon JJ, Hand I, Noble L, Kim MH, Conroy J; International Conference on AIDS.
Int Conf AIDS. 1992 Jul 19-24; 8: C357 (abstract no. PoC 4687).
Albert Einstein College of Medicine, Bronx Lebanon Hospital, Dept. of Peds., N.Y. 10457.
OBJECTIVES: To identify risk factors for HIV seropositivity in the newborn. METHODS: Maternal and newborn blood specimens were collected on 385 consecutive mother-infant pairs. In addition, maternal drug usage was evaluated using maternal history and toxicological screening of maternal blood and urine and newborn blood, urine and meconium. All information was numerically coded to insure anonymity. RESULT: The prevalence of HIV seropositivity in newborns during the study period was found to be 3.1% (12/385). The incidence of HIV seropositivity among infants admitted to the neonatal intensive care unit (NICU) was 8.8% (7/80), significantly different (p less than .005) from the 1.6% (5/305) incidence in those admitted to the well baby nursery (WBN). Among HIV seropositive infants 75% (9/12) were born to maternal drug users whereas 32% (119/373) of the HIV seronegative infants had drug using mothers (p less than .01). The relationship on HIV seropositivity and drug use was assessed in the NICU and WBN: TABULAR DATA, SEE ABSTRACT VOLUME. There was no significant difference in HIV seroprevalence among drug exposed and non drug exposed infants in the WBN. CONCLUSIONS: Infants of drug using mothers admitted to the NICU appear to be at particularly high risk for HIV seropositivity.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- HIV Infections
- HIV Seropositivity
- HIV Seroprevalence
- Humans
- Incidence
- Infant
- Infant, Newborn
- Intensive Care Units, Neonatal
- Meconium
- Mothers
- Nurseries
- Prevalence
- Risk Factors
- Substance-Related Disorders
- methods
Other ID:
UI: 102200071
From Meeting Abstracts