Boue F, Pons JC, Keros L, Chambrin V, Papiernik E, Henrion R, Delfraissy JF; International Conference on AIDS.
Int Conf AIDS. 1990 Jun 20-23; 6: 144 (abstract no. Th.C.44).
Service de Medecine Interne et de Gynecologie-Hopital Antoine Beclere-Clamart-92 141-France
OBJECTIVE: Recent European studies have shown an observed incidence of transmission of 30%. However, most of the women belong to CDC groups II and III and they are conflicting results concerning the relationship between mother's status and rate of perinatal transmission. METHODS: Between October 1985 and December 1989, we conducted a follow up study of 3 groups of HIV positive women. Group 1: pregnant women with delivery (n=132), group 2: pregnant women with induced abortion (n=146), group 3: HIV +non pregnant women (n=212). The three groups were studied for risk factors, clinical status, immunological and virological parameters. The outcome of children (with a follow up greater than 15 months: n : 88) was determined on clinical and virological parameters. RESULTS: TABULAR DATA, SEE ABSTRACT VOLUME. CONCLUSION: The incidence of perinatal transmission is higher when HIV positive mothers have CD4 less than 150 /mm3, positive antigenemia p 24 and displayed a high replication rate of HIV in cultures. These women with high risk of transmission have to be informed. Moreover this subgroup of women could constitute a group for therapeutic trials during pregnancy.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Child
- Disease Transmission, Vertical
- Female
- Follow-Up Studies
- HIV Infections
- HIV Seropositivity
- HIV-1
- Humans
- Mothers
- Pregnancy
- Risk Factors
- transmission
Other ID:
UI: 102181655
From Meeting Abstracts