Muloko N, Ossari S, Lefandi A, Rakibou B, Loudy Z; International Conference on AIDS.
Int Conf AIDS. 1993 Jun 6-11; 9: 262 (abstract no. PO-A31-0763).
Centre International de Recherche Medicale de Franceville, Centre Hospitalier de Franceville, Gabon.
The purpose is to determine the frequency of co-infection with HIV/HTLV in a cohort of 674 adult individuals living in a area of low prevalence for HIV (< 1%) but where the rate of positivity to HTLV reaches 10%. This preliminary cross-sectional study will be used as the basis for studying, using well-defined biological markers, the pathologic sequelae associated with the co-infection. The virologic diagnosis is based on the detection of serum antibodies directed against specific proteins of the virus concerned. The positivity criteria are those fixed by WHO. This study confirms the advance of HIV-2, into the study area due likely to population migration to the region where the only cases described were from West African individuals. The data show, however, that people infected with HIV-1 seem to be threatened by a potential risk of super-infection with HIV-2; HTLV is associated with HIV only in case of doubly-infected HIV-1 and HIV-2 older individuals. Both HIV-1 and HIV-2 preferentially and significantly infect younger women by comparison with HTLV which affects mostly older women.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Adult
- Cluster Analysis
- Cross-Sectional Studies
- Deltaretrovirus
- Deltaretrovirus Antibodies
- Deltaretrovirus Infections
- Female
- HIV Infections
- HIV Seropositivity
- HIV-1
- HIV-2
- Human T-lymphotropic virus 1
- Human T-lymphotropic virus 2
- Humans
Other ID:
UI: 102203624
From Meeting Abstracts