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In 2004, CDC and the NIH National Cancer
Institute (NCI) began a collaboration to measure the
prevalence of 100 gene variants of public health
interest in the U.S. population. The working group uses
data derived from DNA samples collected during the third National Health
and Nutrition Examination Survey (NHANES).
NHANES is a nationally representative survey of the U.S.
population conducted by the CDC National Center for
Health Statistics. The NHANES database includes
thousands of data points on survey participants,
including demographic, health history and health
behavior characteristics; physical and physiological
measurements; and detailed nutritional and biochemical
analyses
The CDC-NCI working group also developed a collaborative
plan to investigate and elucidate correlations between
the gene variants (genotypes) and multiple health
outcomes (phenotypes), including asthma, diabetes,
obesity, and infectious diseases. Results from these
studies will be used to calculate genotype prevalence
estimates for a nationally representative sample of the
U.S. population. These data will provide the basis for
multiple analyses of gene-disease associations and
gene-environment interactions. |
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National Health and Nutrition Survey (NHANES) III DNA Bank: Gene Variants Important to Public Health
Genomics and Population Health: United States 2003 Report |
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Consent for Genetic Research in a General Population: The NHANES Experience
To determine the socio-demographic factors associated with consent for storage of DNA for future genetic research. |
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NHANES III DNA bank: prevalence of gene variants of public health significance
Poster presentation for the May 5, 2003. Genomics and the Future of Public Health Symposium Poster Session,
Lindegren ML, CDC Working Group.
Office of Genomics and Disease Prevention, CDC |
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