Scientific Opportunities: Life Sciences

Overview | Macromolecular Crystallography | Structure and Dynamics | Biological and Biomedical Imaging

Overview

A scanning transmission x-ray microscope image of a fibroblast ( a cell that produces collagen fibers, which make up connective tissue) that has been labeled with gold particles to identify tubulin (a cytoskeleton component).

One major thrust of life sciences research at synchrotron sources is protein crystallography, which uses x-rays to see the crystal structure of proteins and other biological molecules. Other life sciences research focuses on using x-rays to image tissue and cells, and to "watch" biological processes that occur on very short time scales, such as protein folding. The information learned from these fundamental studies is used to design drugs and treatments for disease, to predict and detect disease, and to understand the vast array of biological processes that govern life.

However, this important research cannot continue to advance without producing x-rays that are far brighter and more focused than those currently available at any other light source worldwide. The light available at NSLS-II will lead the world in brightness, opening up many new research pathways in the life sciences and drawing in the best biological and medical researchers.

Last Modified: March 4, 2008
Please forward all questions about this site to: Gary Schroeder

One of ten national laboratories overseen and primarily funded by the Office of Science of the U.S. Department of Energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences, as well as in energy technologies and national security. Brookhaven Lab also builds and operates major scientific facilities available to university, industry and government researchers. Brookhaven is operated and managed for DOE’s Office of Science by Brookhaven Science Associates, a limited-liability company founded by Stony Brook University, the largest academic user of Laboratory facilities, and Battelle, a nonprofit, applied science and technology organization.

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