Alpha-1 Antitrypsin
Alpha-1 antitrypsin is a major protein in the blood that it is produced mainly in liver cells. When you don't have enough alpha-1 antitrypsin, you might have Alpha-1 Antitrypsin Deficiency, sometimes called Alpha-1. Alpha-1 can affect two major organs in the body - the lungs and the liver. The reason is because the defective protein that characterizes Alpha-1 is important to both of these vital organs.
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When Alpha-1 affects the lungs, it can cause COPD and is called inherited emphysema.
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When Alpha-1 affects the liver, it is called inherited liver disease.
This information has been approved by Ron Balkissoon, MD (April 2006).
