The High-Performance Computing Group (Code 606.2) manages and operates the NASA Center for Computational Sciences (NCCS), one of the world's most powerful supercomputer and data storage centers. The NCCS supports NASA missions and programs as well as university communities on a national basis.

The mission of the NCCS is to enable Earth and space sciences research through computational modeling by providing access to:
- state-of-the-art high-performance computing,

- leading-edge mass storage technologies,

- high-speed networking, and

- HPC expertise.

Planning also plays a key role in the NCCS as technology evolves in an increasingly dynamic environment. The NCCS exploits existing contractual vehicles to bring the latest advanced technology to the its user community. Cooperative partnerships with other centers, agencies, and vendors provide other means of advancing technological support to users.

The NCCS supports the following primary projects:
- Global Modeling and Assimilation Group (GMAO), which develops and uses satellite observations by integrating the tools of models and assimilation systems

- Goddard Institute for Space Studies (GISS), which emphasizes a broad study of global climate change

Other Earth and space sciences research supported by the NCCS includes:
- Global Modeling Initiative, which is developing and maintaining a model to use to assess the impact of various perturbations on atmospheric composition and chemistry

- Atmospheric processes systems modeling and data analysis (mesoscale atmospheric processes, climate and radiation processes, atmospheric chemistry and dynamics)

- Terrestrial physics modeling (geodynamics, space geodesy and solid Earth physics)

- Hydrospheric processes (oceans and ice, and hydrological sciences)

- Microgravity research