Biography

Dr. Sherman received an M.D. from the University of Chicago in 1983, completed a pathology residency at the New England Deaconess Hospital in 1987 and a fellowship in cytopathology at Montefiore Medical Center in 1988. Prior to joining the National Cancer Institute in 2001, he was an Associate Professor of Pathology and Director of Breast Pathology at The Johns Hopkins University School of Medicine.

Research Interests

• Molecular epidemiology of gynecologic tumors and breast cancer, including studies of tissue biomarkers to compare risk factors by histopathologic type and to elucidate different mechanisms of carcinogenesis
• Natural history of cancer precursors with emphasis on early morphologic and molecular changes
• Hormonal carcinogenesis with emphasis on expression and actions of reproductive hormones in breast cancer
• Development of high throughput methods for analysis of tissues, especially the development of tissue microarrays
• Identification of biomarkers for screening and understanding imtermediate stages in carcinogenesis

Keywords

• Breast Cancer, Gynecologic Cancer, Papillomavirus, hormonal carcinogenesis, molecular pathology

Selected Publications

• Sherman ME, Lorincz AT, Scott DR, Wacholder S, Castle PE, Glass AG, Mielzynska I, Rush BB, Schiffman M. "Performance of cytology and human papillomavirus testing in identifying women at risk for cervical neoplasia: A ten-year cohort analysis of 20,810 women." J Natl Cancer Inst 95:46-52, 2003.
• Sherman ME, Devesa SS. "Analysis of racial differences in incidence, survival, and mortality for malignant tumors of the uterine corpus." Cancer 2003 Jul 1; 98(1):176-86.
• Fergenbaum JH, Garcia-Closas M, Hewitt SM, Lissowska J, Sakoda LC, Sherman ME. "Loss of antigenicity in sotred sections of breast cancer tissue microarrays." Cancer Epidemiol Biomark Prev 2004 Apr; 13(4):667-72.
• Sherman ME, Berman J, Birrer MJ, Cho KR, Ellenson LH, Gorstein F, Seidman JD. "Current challenges and opportunites for research on borderline ovarian tumors." Hum Pathol 2004 Aug; 35(8):961-70.
• Althuis MD, Fergenbaum JH, Garcia-Closas M, Brinton LA, Madigan MP, Sherman ME. "Etiology of hormone receptor-defined breast cancer: a systematic review of the literature." Cancer Epidemiol Biomark Prev 2004 Oct; 13(10):1559-68.

Collaborators

DCEG Collaborators

• Mark Schiffman, M.D., M.P.H., Montserrat Garcia-Closas, M.D., Ph.D, Louise Brinton, Ph.D., Philip Castle, Ph.D., Sophia Wang, Ph.D., James Lacey Jr., Ph.D., Mark Greene, M.D., Susan Devesa, Ph.D.

Other NCI Collaborators

• Diane Solomon, M.D., Barbara Vonderhaar, Ph.D., William Anderson, M.D., Stephen Hewitt, M.D., Ph.D.

Other ScientificCollaborators

• Michelle Althuis, Ph.D., Georgetown University, Washington, D.C.
• Concepcion Bratti, M.D., Costa Rican Social Security, San José, Costa Rica
• Adi Gadzar, M.D., Ph.D., University of Texas Southwestern Medical School, Dallas, Texas
• Andrew Glass, M.D.; David Scott, M.D., Portland Kaiser-Permanente, Portland, Oregon
• Rolando Herrero, M.D., Ph.D., Ministry of Health, San Jose, Costa Rica
• Olga Ioffe, M.D., University of Maryland School of Medicine, Baltimore, Maryland
• Paul Levine, M.D., George Washington University School of Public Health, Washington, D.C.
• Jolanta Lissowska, Ph.D., Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
• George Mutter, M.D., Brigham and Young Women’s Hospital, Boston, Massachusetts
• Brigitte Ronnett, M.D., Johns Hopkins University School of Medicine, Baltimore, Maryland
• Dominic J. Smiraglia, Ph.D., Roswell Park, Buffalo, New York