Fong I, Elzawi A, Howard R, Simbul M; International Conference on AIDS.
Int Conf AIDS. 1991 Jun 16-21; 7: 282 (abstract no. M.B.2401).
St. Michael's Hospital, University of Toronto, Toronto, Canada
OBJECTIVE: To determine the incidence of cardiac abnormalities in HIV infected patients. METHODS: Unselected patients (pts.) with HIV infection admitted to hospital or seen in the clinic were studied. A group of healthy controls were also assessed for comparison. Assessment included physical examination, electrocardiogram (ECG), chest x-ray, echocardiogram (echo) and doppler studies. Statistical analysis of the results was done by Fisher's exact test. Trivial abnormalities in both groups were not counted. RESULTS: Of the 93 pts. with HIV infection, 78 had AIDS or ARC and 15 were asymptomatic or mildly symptomatic; 88 were males (m) and 5 females (f) with a mean age of 36.4 +/- 10 years. The 20 controls mean age was 27 +/- 7 years with 17 m and 3 f. Nineteen pts. (20.4%) had abnormalities on echo versus 0 (0%) of controls, p=0.03. Seven pts. (7.5%) had pericardial effusion (one moderate and the rest small), 8 pts. (8.6%) had valvular abnormalities, and 4 pts. (4.3%) had left ventricular dysfunction. Eighteen pts. had repeat studies (avg. 12 months later) and of these 6 pts. (33.3%) showed new abnormalities on echo and 2 pts. (11.1%) showed resolution of previous abnormalities. The doppler was abnormal in 8 pts. (8.6%) and the ECG abnormal in 9 pts. (9.7%), but no controls showed any abnormalities, not significant. CONCLUSION: Cardiac abnormalities in HIV pts. by echo studies are more frequent than healthy controls, but most abnormalities are clinically silent.
Publication Types:
Keywords:
- AIDS-Related Complex
- Acquired Immunodeficiency Syndrome
- Echocardiography
- Electrocardiography
- Female
- HIV Infections
- HIV Seropositivity
- Heart Defects, Congenital
- Humans
- Incidence
- Male
- Pericardial Effusion
- Ventricular Dysfunction, Left
- abnormalities
- ultrasonography
Other ID:
UI: 102183320
From Meeting Abstracts