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New Approaches to Prevent Hypoglycemia in Patients with Diabetes
Release Date: July 27, 2001
Announcement Number: RFA-DK-01-032
Application Receipt Date:
November 21, 2001
Letter of Intent Date: October 17, 2001

Funding Contact: NINDS Funding
Program Area: Neural Environment

Brief Description:
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Child Health and Human Development (NICHD), the National Institute of Nursing Research (NINR) and the Juvenile Diabetes Research Foundation International (JDRF) solicit applications for clinical studies designed to enhance understanding and prevention of hypoglycemia in patients with diabetes. Large clinical trials have demonstrated the efficacy of intensified glucose control in the prevention of the long-term complications of diabetes. However, episodes of severe hypoglycemia may complicate intensified treatment and are often a major obstacle to the achievement of euglycemia in many patients. This RFA solicits clinical studies to 1) define and characterize hypoglycemia in diabetic individuals and 2) develop new approaches to prevent the development of hypoglycemia or to ameliorate its effects in individuals with diabetes.

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