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Neuroprotectants as Medical Countermeasures against Chemical Threat Agents: Request for Information (RFI)
Release Date: March 5, 2007
Announcement Number: NOT-NS-07-007

Funding Contact: David Jett, Ph.D.
Program Area: Technology Development

Brief Description:
The National Institute of Neurological Disorders and Stroke (NINDS) is seeking information on the development of therapeutics with indications for protecting the nervous system from cellular and tissue damage caused by acute exposure to chemical threat agents. Chemical threat agents are toxic chemicals that could be used in a terrorist attack against civilians, or chemicals that could be released at toxic levels by accident or natural disaster. Since chemically-induced neurological damage may share common mechanisms with damage caused by trauma and/or disease, the NINDS also requests information on general molecular and cellular processes of neurodegeneration, and how an understanding of these processes may be used to develop safe and effective medical countermeasures against chemical threats.

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