Current Projects

Prostate Return to top

Nitrosamines and prostate cancer
Serum insulin and glucose and prostate cancer
Post-intervention follow-up of prostate cancer
Cohort consortium study of prostate cancer risk, sex steroid hormone metabolism, and IGFs
Weight, weight change, and BMI and prostate cancer
Dietary carotenoids and retinol and prostate cancer
Genes involved in insulin signaling/obesity and insulin resistance and chronic inflammation pathways with prostate cancer (& possibly gallbladder)
Genetic variants in genes relevant to energy balance and prostate cancer
C-reactive protein and prostate cancer
Family history and prostate cancer
Genetic polymorphisms in vitamin E transport/metabolism genes, vitamin E supplementation, and prostate cancer
Genetic variants in inflammatory and respiratory burst pathway and prostate cancer risk
Selenoprotein genetic polymorphisms in relation to prostate cancer risk
Phytanic acid, genetic variation in branch-chain fatty acid oxidation pathways, and prostate cancer risk
Adipokines and risk of prostate cancer
Serum ß-carotene, a-tocopherol, and retinol and prostate cancer survival in the ATBC study
The relationship between serum creatinine and prostate cancer

Post-intervention follow-up of lung cancer
P53 mutations (frequency, type, expression of the p53 protein) in lung cancer; Apoptosis and expression of bcl-2 and mcl-1 genes in lung cancer
Screening of lung cancer with tumour markers in male smokers with negative chest radiography
Biochemical measure of total antioxidant capacity and lung cancer
Beta-carotene, lung cancer tissue study
Telomere length and lung cancer
Family history and lung cancer
Lung cancer, smoking history and candidate genes for both
Dietary patterns and lung cancer
Serum chlamydia and lung cancer
Mitocondrial DNA copy number and lung cancer
Whole genome scans of lung cancer

Pancreatitis polymorphisms and pancreatic cancer
Insulin pathway polymorphisms and cox and inflammation and DNA repair & carcinogenic metabolism polymorphisms and pancreatic cancer
BMI, adiponectin, c-peptide, CPR and (leptin) and pancreatic cancer
Whole diet & pancreatic cancer
Baseline serum carotenoids, retinol, alpha-tocopherol & pancreatic cancer
Cox polymorphisms and pancreatic cancer
Proteomics and pancreatic cancer
Polymorphisms in folate, selenium and pancreatic cancer
Telomere length and pancreatic cancer
Whole genome scan pancreatic cancer in consortium
Serum pepsinogen and pancreatic cancer
Uracil misincorporation, global methylation, p53 strand breaks and pancreatic cancer
Helicobacter species
Markers of oxidative stress
TGF-beta
Methylation markers for risk prediction
Plasma levels of advanced glycation end product and soluble receptor for advanced glycation end product and risk of pancreatic cancer
Mitocondrial DNA copy number and pancreatic cancer
Obesity and risk of pancreatic cancer in a pooled stydy of NCI-DCEG cohorts

Aromatic amine hemoglobin adducts (from RBCs or whole blood) and serum PAH-albumin adducts and bladder cancer
Whole genome scan of bladder cancer

Serum pepsinogen and risk of gastric cardia and non-cardia cancers: A prospective study
Serum ghrelin and gastric cancer
Serum ferritin, transferrin, and CRP and gastric cancer

Serum vitamin E and esophageal cancer in ATBC
Serum factors related to one-carbon metabolism and risk of stomach and esophageal cancer
Serum ghrelin and espophageal cancer
Serum ferritin, transferrin, and CRP and esophageal cancer

Serum IGF-1 and IGFBP-3 and renal cell cancer
Dietary vitamin D and renal cell carcinoma
Serum insulin and glucose and renal cell carcinoma
Antioxidants, fruits and vegetables in relation to renal cell cancer
BMI, hypertension, dietary intake, and renal cancer
Vitamin D (serum and genetics) and renal cell carcinoma
Serum factors related to one-carbon metabolism and risk of kidney cancer
Heavy metal exposure and renal cell carcinoma
Association of SNPs in genes in VHL-HIF Pathway and susceptibility of kidney cancer (iSelect)
Flavonoid intake and the risk of renal cell carcinoma
GWAS of kidney cancer

Immunological markers and multiple myeloma (also including genetic polymorphisms)
Physical activity and NHL
Genetic variations in MTHFR, TYMS, SHMT1, MTR, and MTRR and risk of lymphoid cancers
Serum indicators of folate, B12, B6, homocysteine and risk of lymphoid cancers
Telomere length and hematopoietic cancer
Serum vitamin D and lymphoma
Serum IGF, insulin, glucose and lymphoma
Genomic DNA methylation and lymphoma
Mitocondrial DNA copy number and hematopoietic cancer

Diet (antioxidants, fruits, vegetables) and laryngeal cancer
HPV-16, HSV-1 and head and neck cancers
Serum factors related to one-carbon metabolism and risk of oropharynx/larynx cancers
Tooth loss and head and neck cancer

Height and risk of cancer
Genetic factors related to one-carbon metabolism and risk of other cancers (colorectal, stomach, kidney, liver, biliary, oropharynx, bladder, pancreas)
Retrospective and prospective risk assessments for serum nutrients and cancer (lung, GI, prostate)
Serum carotenoids and risk of cancers of the lung, prostate, bladder, colon, rectum, stomach
Comparison of prospective and retrospective data in lung
Toenail selenium concentration in relation to risk of prostate, colorectal, and other cancers
Serum vitamin D and risk of several cancers (renal, pancreatic, lymphoma, stomach, esophagus, prostate, melanoma, larynx, liver/biliary, oropharynx, bladder, colorectal, lung, prostate)
Tooth loss and all cancers in the ATBC study

Carotenoids and total mortality
Amyotrophic lateral sclerosis, intervention, dietary factors, and serum micronutrients
Heavy metals and cardiovascular disease
Effect of alpha-tocopherol and beta-carotene supplements on, and risk factors of diabetes
Alcohol consumption, ADH3 polymorphisms, and all-cause mortality
Dietary patterns and the risk of cardiovascular disease
Glycemic index and the risk of cardiovascular disease
Glycemic index and the risk of diabetes
Intake of iron and iron status and the risk of coronary heart disease
Effect of alpha-tocopherol and beta-carotene supplements on neurologic disorders (dementia, Parkinsons disease, and multiple sclerosis)
Cross-sectional study of physical activity and biological markers (IGF-1, IGFBP-3, insulin, total testosterone, free testosterone, dihydrotestosterone, androstenedione, DHEAS, androstanediol glucuronide, estradiol, estrone, and SHBG)
Determinants of serum alpha- and gamma-tocopherol levels
Hazard analysis of smoking cessation relapse
Hazard analysis of smoking abstinence
Smoking cessation, medical and smoking history, and neurotransmitter variants
Predictors of serum vitamin D
Tooth loss and CHD death and total mortality
CGEMS added value
The joint modeling of smoking pattern and chronic disease
GWAS marker predictors of micronutrient, anthropometric, and other biometric measures