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Diet Composition and Energy Balance (R01)
Release Date: February 14, 2007
Announcement Number: PA-07-218
Application Receipt Date:
June 5, 2007
October 5, 2007
February 5, 2008
June 5, 2008
October 5, 2008
February 5, 2009
June 5, 2009
October 5, 2009
February 5, 2010
Funding Contact: Merrill Mitler, Ph.D.
Program Area: Systems and Cognitive Neuroscience
Brief Description:
Overweight and obesity have increased dramatically in prevalence in the US. More than 66 percent of the US population is
overweight (BMI ≥25) and 32 percent meet criteria for obesity (BMI ≥30). Obesity is particularly prevalent among some minority
populations, such as African American, Hispanic, and Native American women. Overweight prevalence is also increasing in children,
with more than 17 percent of children and adolescents considered overweight and an additional 16 percent at risk for overweight.
Obesity is associated with numerous serious and chronic diseases, including type 2 diabetes, cardiovascular disease, sleep
apnea, and certain forms of cancer. The causes of obesity are complex, and involve both genetic and environmental components.
Environmental changes over the past two decades have increased sedentary behaviors, decreased physical activity, and increased
consumption of more energy dense foods and larger portion sizes. Although an imbalance in energy consumption and expenditure
are required to promote inappropriate weight gain, the relative contributions of each to the burgeoning obesity epidemic remain
in dispute.
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