Pouchot J, Persoz A, Leplege A, Meyer L; International Conference on AIDS.
Int Conf AIDS. 1998; 12: 249 (abstract no. 14337).
Inserm U292 Hopital De Bicetre, Kremlin Bicetre, France.
BACKGROUND: HIV infection is now being considered as a chronic disease and quality of life (QoL) assessment is therefore of primary importance. The objectives were to assess the QoL of HIV-infected individuals enrolled in the French SEROCO cohort with MOS-SF36, and to examine the psychometric properties of SF36 in this study population. METHODS: 222 HIV-infected individuals completed the MOS-SF36 (36 items, 8 scales) at entry in the study (D0), 15 days later (D15), and every 6 months. Descriptive analysis of QoL data obtained at DO and some psychometric properties of the MOS-SF36 are presented here. RESULTS: Psychometric properties of the MOS-SF36 seem maintained in the context of an HIV-infected population. Reliability of the 8 scales appreciated by the test-retest between D0 and D15 was moderate to good with intraclass correlation coefficients ranging between 0.64 and 0.86. Internal consistency was good for the 8 scales with Cronbach's coefficients ranging between 0.80 and 0.94. Construct validity appreciated by a component analysis revealed a preserved structure with the 8 scales loading on 6 main axis. TABULAR DATA, SEE ABSTRACT VOLUME. CONCLUSIONS: Use of a generic health status instrument such as the MOS-SF36 is appropriate in HIV-infected populations. These preliminary results give additional information regarding the consequence of the disease in different health status components and may help to compare disease outcome related to patients' characteristics.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Evaluation Studies
- Genes, mos
- HIV Infections
- HIV Seropositivity
- Health Status
- Health Status Indicators
- Humans
- Life
- Psychometrics
- Quality of Life
- genetics
- methods
Other ID:
UI: 102228613
From Meeting Abstracts