The FY 2003 President's Budget for NIH (including AIDS) increases from $23,729,584,000 in FY 2002 to $27,432,075,000 in FY 2003, an increase of 15.6 percent. A substantial part of this increase will support new initiatives in bioterrorism research at NIAID. AIDS funding increases by 10.1 percent in FY 2003, from $2,514,954,000 in FY 2002 to $2,769,997,000.
The FY 2003 President's Budget for NIA (including AIDS) is $971,709,000 an increase of 8.4 percent over the FY 2002 comparable estimate of $896,064,000. Funding for AIDS related research increases from $4,985,000 in FY 2002 to $5,379,000 in FY 2003, an increase of 7.9 percent.
One of NIH's highest priorities is the funding of medical research through research project grants (RPGs). Support for RPGs allows NIH to sustain the scientific momentum of investigator-initiated research while providing new research opportunities. The FY 2003 NIA request provides an average cost increase for competing RPGs at the Biomedical Research and Development Price Index (BRDPI), estimated at 4.0%. Noncompeting RPGs will receive increases of 3 percent on average for recurring direct costs.
The FY 2003 request includes funding for 1,456 research project grants, compared to 1,402 in FY 2002 and 1,276 in FY 2001. Of these 1,456 awards, 436 will be competing research project grants and 1,020 will be noncompeting awards. In addition, the request includes funding for 78 SBIR/STTR grants.
Funding for the Centers mechanism increases by 6.0 percent over the FY 2002 level.
Promises for advancement in medical research are dependent on a continuing supply of new investigators with new ideas. In the FY 2003 request, NIA will support 584 pre- and postdoctoral trainees in full-time training positions. An increase of 4.3 percent over FY 2002 levels is provided for stipends and training-related expenses (e.g., health insurance, research supplies and equipment, and travel to scientific meetings).
The FY 2003 request includes an increase of 7.8 percent over the FY 2002 level for Other Research. Most of this increase will support 192 positions in the Research Career Awards Program, including the AD Clinical Research and Training Awards initiative.
Funding for Contracts in FY 2003 increases by 6.9 percent over the FY 2002 level to support NIA's share of the NIH Extramural Clinical Loan Repayment Program.
The FY 2003 request includes a 8.9 percent increase over the FY 2002 level for Intramural Research and an 8.8 percent increase over the FY 2002 level for Research Management and Support.
(Contact: Mr. Kevin Laser, BO, 301-496-9147)
S. 2059 Alzheimer's Disease Research, Prevention, and Care Act of 2002 - On March 21, 2002, Senator Barbara Mikulski (D-MD), Chairwoman, Senate Health, Education, Labor and Pensions Subcommittee on Aging introduced S. 2059, the Alzheimer's Disease Research, Prevention, and Care Act of 2002 to the Committee on Health, Education, Labor, and Pensions. If passed, the bill would amend the Public Health Service Act to expand Alzheimer's disease research at the National Institutes of Health (NIH), and expand and reauthorize the Alzheimer's Demonstration Grant Program.
House Appropriations Subcommittee FY 2003 Budget Hearings - On March 13, 2002 the House Appropriations Subcommittee on Labor, HHS, Education (Representative Ralph Regula [R-OH], Chairman) held an overview hearing to discuss the FY 2003 budget for NIH. Ruth Kirschstein, Acting Director of NIH, testified and was accompanied by Dr. Richard Hodes, NIA, and the other NIH IC Directors.
House Appropriations Subcommittee FY 2003 Budget Theme Hearing - On March 14, 2002, the House Appropriations Subcommittee on Labor, HHS, Education (Representative Ralph Regula [R-OH], Chairman) held the first in a series of theme hearings as part of the FY 2003 NIH budget hearings. This hearing was entitled, "From Bench to Bedside and Beyond." NIH witnesses were: Ruth Kirschstein, Acting Director of NIH; Allen Spiegel, Director of NIDDK; Andrew von Eschenbach, Director of NCI; Richard Hodes, Director of NIA; Audrey Penn, Acting Director of NINDS; and Anthony Fauci, Director of NIAID.
House Appropriations Subcommittee Second FY 2003 Budget Theme Hearing - On March 19, the House Appropriations Subcommittee on Labor, HHS, Education (Representative Ralph Regula [R-OH], Chairman) held the second in a series of theme hearings as part of the FY 2003 NIH budget hearings. This hearing was entitled, "Fundamental Research: Biomedical Science in the Future." NIH witnesses were: Ruth Kirschstein, Acting Director of NIH; Marvin Cassman, Director of NIGMS; James Battey, Director of NIDCD; Richard Nakamura, Acting Director of NIMH; Glen Hanson, Acting Director of NIDA; Judith Vaitukaitis, Director of NCRR; and Ellie Ehrenfeld, Director of CSR.
Senate Appropriations Subcommittee Hearing on the President's FY 2003 Budget - On March 21, the Senate Appropriations Subcommittee on Labor, HHS, and Education (Senator Tom Harkin [D-IA], Chairman) held a hearing on the President's FY 2003 Budget request for NIH. Ruth Kirschstein, Acting Director of NIH, testified and was accompanied by Dr. Richard Hodes, NIA, and the other NIH IC Directors.
Field Hearing on Alzheimer's Disease Research - On April 2, 2002, Senator Barbara Mikulski (D-MD), Chairwoman, Senate Health, Education, Labor and Pensions Subcommittee on Aging, held a hearing on Alzheimer's disease research at the Gerontology Research Center in Baltimore, MD. The Senator toured the facility prior to the hearing. Dr. Judy Salerno, Deputy Director of NIA, testified concerning research on Alzheimer's disease.
House Appropriations Subcommittee FY 2003 Budget Theme Hearing - On April 9, The House Appropriations Subcommittee on Labor, HHS, Education (Representative Ralph Regula [R-OH], Chairman) held the third in a series of theme hearings as part of its review of the FY 2003 NIH budget hearings. This hearing was entitled, "Collaborations in Research." NIH witnesses were: Ruth Kirschstein, Acting Director of NIH; Stephen Katz, Director of NIAMS; Duane Alexander, Director of NICHD; Donna Dean, Acting Director of NIBIB; Gerald Keusch, Director of FIC; John Ruffin, Director of NCMHD, and Stephen Straus, Director of NCCAM.
House Appropriations Subcommittee FY 2003 Budget Theme Hearing - On April 16, the House Appropriations Subcommittee on Labor, HHS, Education (Representative Ralph Regula [R-OH], Chairman) held the fourth in a series of theme hearings as part its review of the FY 2003 NIH budget hearings. This hearing was entitled, "Disease Prevention." NIH witnesses were the following: Ruth Kirschstein, Acting Director of NIH; Patricia Grady, Director of NINR; Donald Lindberg, Director of NLM; Kenneth Olden, Director of NIEHS; Paul Sieving, Director of NEI; Lawrence Tabak, Director of NIDCR; Claude Lenfant, Director of NHLBI; Francis Collins, Director of NHGRI; and Raynard Kington, Acting Director of NIAAA.
Senate Hearing on Alzheimer's Disease Research - On April 30, 2002, the Senate Appropriations Subcommittee on Labor, HHS, Education (Tom Harkin [D-IA], Chairman) held a hearing to discuss Alzheimer's disease research. Dr. Richard Hodes, Director of NIA, testified on the latest advances in Alzheimer's disease research.
Wisconsin Public Health Forum - On May 4, 2002, Congressman David Obey (D-WI) and Congressman Ralph Regula (R-OH), the Chairman of the House Appropriations Subcommittee on Health, sponsored a public health forum at the Marshfield Clinic in Marshfield, Wisconsin and at the Wausau Hospital in Wausau,Wisconsin. Dr. Francis Collins, NHGRI, Dr. Stephen Katz, NIAMS, Dr. Stephen Straus, NCCAM, and Dr. Richard Hodes, NIA, participated in this event.
Ohio Public Health Forum - On May 11, 2002, Congressman Ralph Regula (R-OH), the Chairman of the House Appropriations Subcommittee on Health, and Congressman David Obey (D-WI) sponsored a public health forum in Canton, Ohio. Dr. Francis Collins, NHGRI, Dr. Allen Spiegel, NIDDK, Dr. Duane Alexander, NICHD, Dr. Donald Lindberg, NLM, and Dr. Judy Salerno, NIA, participated in this event.
Alzheimer's Association Public Policy Forum - On April 29, 2002, NIA Director, Dr. Richard Hodes gave a scientific presentation to the Alzheimer's Association Public Policy Forum on the latest advances in Alzheimer's disease research.
The Comparative Biology of Aging Workshop (exploratory) was held February 6-7, 2002. The purpose of the workshop was to gather information on possible comparative biology approaches to the study of aging and on relevant organisms for the study of aging. Our aim was to stimulate new approaches toward understanding the molecular bases for differences in aging rates and life expectancy between species. Such an understanding would make a major contribution towards clarifying the causes of the phenotypes associated with aging and what "times" aging in humans with tremendous potential impact on the quality of life of the elderly. The workshop highlighted current and potential aging-research with a variety of organisms. Jill Carrington of the NIA and a group of investigators, including Steven Austad, Caleb Finch, Michal Jazwinski, Richard Miller, George Taffet and Richard Weindruch co-organized the workshop. It was divided into four major sessions titled "Comparative Biology of Aging", "Comparative Biodemography", "Toward Comparative Study of Biochemical Aging Mechanisms", and "Comparative Genomics". The participants at the workshop shared data and information on a wide variety of species, including not only the traditional animal models used for studying aging {rats (Marco Pahor), mice (Richard Miller, Jan Vijg), fruit flies (Marc Tatar, James Carey, David Promislow), nematodes (Thomas Johnson), yeast (Michal Jazwinski)}, but also fish {including xiphophorus (Ronald Walter, Stevn Kazanis), guppies (David Reznick), zebrafish (Glenn Gerhard), rockfish (Gregor Cailliet)}, birds {Japanese quail (Mary Ann Ottinger), budgiregars (Steven Austad)}, non-human primates {lemurs, macaques, chimpanzees, baboons (Mary Lou Voytko, Caleb Finch, Marc Tatar)}, other insects {honey bees (Kim Hughes), butterflies and grasshoppers (Marc Tatar)}, and other mammals {naked mole rats (Timothy O'Connor), dogs (Elizabeth Head), bats (Jerry Wilkinson), humans (George Martin, John Postlethwait, George Taffet, Woodring Wright)}, and even plants (Deborah Roach). All of this was placed solidly within a framework of human aging by both introductory and summary presentations. It is expected that the information presented at this workshop will be the foundation for a 2003 initiative in comparative biology of aging. This initiative will be presented at a future Council meeting. In addition, an article summarizing major points of the workshop is being prepared by BAP staff to be published on the Science SAGE web site. (Contact: Dr. Jill Carrington, BAP, 301-496-6402)
The Workshop on Genomic and Genetic Tools for the Zebrafish (exploratory) was held on April 1-2, 2002. This was an activity of the Trans-NIH Zebrafish Coordinating Committee, under the leadership of NIDDK and NICHD, to bring together researchers using the Zebrafish model for discussion of future needs for research tools. In view of the interest of the NIA in promoting comparative biology study of aging, and the outstanding utility of this model for genetic and genomic analysis, staff in the Biology of Aging Program, NIA helped to organize and support this workshop. The agenda included updates on Zebrafish genomics projects in progress; introduction and discussion of resources currently under development (including arrays, antibody collections, and strains); and discussion of projects on systematic gene disruption. The workshop concluded with a discussion of the need and mechanisms for possible development of a full-length cDNA set and prioritization of various resources for the research community. Further development of initiatives will take place within the framework of the Trans-NIH committee. (Contact: Dr. Jill Carrington, BAP, 301-496-6402)
The Growth Hormone/Insulin-like Growth Factor-1 (GH/IGF-1) and Aging Tissues Workshop (exploratory) was held on May 1-2, 2002. This is the first in what is expected to be a series of workshops on aging tissues and organs organized by the Systems Branch, BAP. These workshops are intended to gather Systems Branch grantees with other outstanding scientists in areas of common research interest. They are designed to stimulate discussion across tissue lines and promote collaboration between researchers in a variety of related areas. The workshop was initiated in response to the NACA BAP review report encouraging leadership to take advantage of new findings that impact multiple programs and thus, the workshop agenda cut across program lines within BAP. The participants presented data on GH/IGF-I decline with age; IGF-I binding proteins and receptors; GH/IGF-I effects on end organs (muscle, bone, cartilage, prostate, immune system, cardiovascular system); replacing GH/IGF-I in the aged; and experimental approaches toward replacing GH/IGF-I. It is expected that the information presented at this workshop will be the foundation for an initiative in GH/IGF-I and aging to be presented at a future Council meeting. (Contact: Dr. Jill Carrington, BAP, 301-496-6402)
Transgenic Models of Disease Teleconference/MeetingThe "Transgenic Models of Disease Meeting" was held March 6, 2002 at the NIH. The National Institute on Aging (NIA), and the National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Child Health and Human Development (NICHD), and the National Center for Research Resources (NCRR) organized this informational meeting. The intent of the meeting was to discuss the potential of using non-human primates (NHP) as alternatives to mouse transgenic models of neurological diseases. The meeting bought together (in person or by teleconference) NIH extramural program directors and outside experts. The discussion topics included the advantages and disadvantages of current transgenic mouse models of neurological disorders; development of transgenics in other animal species such as rats or dogs; the possible scientific advantages and disadvantages of developing transgenic non-human primate models, including technology development and choice of species; the availability and cost of non-human primates, as well as the length of time for generation of the disease model; and ethics. For further information contact: Dr. Bradley Wise (301) 496-9350.
Workshop on the Genetics of Late Onset Alzheimer's DiseaseThe Neuroscience and Neuropsychology of Aging Program and the Alzheimer's Association cosponsored a one and a half day advisory workshop entitled, "The 2002 Workshop on the Genetics of Late Onset Alzheimer's Disease" on March 18 to 19, 2002 in Bethesda, Maryland. Approximately 100 basic science investigators, Alzheimer's Disease Center directors, and NIH program staff were invited from both extramural and intramural communities. The workshop included presentations from NIH extramural program staff on Institute and NIH policy on the sharing of unique research resources. With an aim to determine availability of unique resources, a recent survey that tabulated the Numbers of available AD and control DNA and cell samples was presented. Presentations were also given concerning plans for the Indiana University Alzheimer's Disease Center as a repository resource. Selected AD geneticists presented their points of view on what new research resources the field needs in order to move forward. Substantive interactions followed during an open discussion of all participants on key issues including cell and DNA banking needs, sample and data sharing, and informed consent. The workshop participants generated a set of suggestions for further research on the genetics of late onset AD. For further information contact: Dr. Marilyn M. Miller at (301) 496-9350.
Alzheimer's Disease Neuroimaging Initiative MeetingThe Neuroscience and Neuropsychology of Aging program sponsored a one-day informational meeting on March 29, 2002, in Bethesda, Maryland, to begin to bring together a consortium of experts on neuroimaging in Alzheimer's disease (AD) and mild cognitive impairment (MCI). Attendees came from academia, pharmaceutical companies, imaging companies, NIH program staff, the NIH Office of the Director, the Food and Drug Association, the Alzheimer's Association, and the Institute for the Study of Aging.
The goal of this initiative is to develop longitudinal studies that will identify the neuroimaging modalities and techniques that are most appropriate for following elderly people as they develop MCI and AD. In addition to providing natural history information, the hope is that neuroimaging markers will allow early identification of those who may benefit from emerging preventative and treatment medications. Representatives from pharmaceutical companies, imaging companies, and advocacy organizations expressed their levels of interest and their concerns about participating in this initiative. NIH staff discussed the conduct of a similar initiative on osteoarthritis that is sponsored by NIAMS and co-sponsored by NIA. Topics discussed by the representatives and by the academic investigators included standardization of imaging protocols and data analysis, advantages and disadvantages of different imaging modalities, investigators' experience with longitudinal imaging studies, criteria for surrogate markers for drug efficacy, and data sharing. The next meeting for this initiative is planned for June 17-18 (see below). For further information contact: Dr. Susan Molchan or Dr. Neil Buckholtz at (301) 496-9350.
Restless Leg Syndrome: Diagnosis and Diagnostic and Epidemiological ToolsThe National Institute on Aging is cosponsoring an advisory workshop, held in Bethesda May 1 to 3, in conjunction with the Restless Legs Syndrome Foundation, as well as the National Institute on Neurological Diseases and Stroke, National Institute of Mental Health, National Institute of Nursing Research, and the National Center for Sleep Disorders Research, to:
Alzheimer's Disease Neuroimaging Initiative MeetingThis advisory meeting will include 180-200 people from academia, pharmaceutical companies, imaging companies, NIH program staff, the NIH Office of the Director, the Food and Drug Association, the Alzheimer's Association, and the Institute for the Study of Aging, and will take place June 17-18, in Bethesda, Maryland. The goal of this initiative is to foster a public-private collaboration for the development of longitudinal studies that will identify the neuroimaging techniques most appropriate for following elderly people as they develop mild cognitive impairment and Alzheimer's disease. In addition to providing natural history information, neuroimaging may allow early identification of patients who may benefit from emerging preventative and treatment medications, and provide a way of monitoring treatments. The meeting will include presentations from academic and pharmaceutical company investigators in methodological aspects of neuroimaging in the context of epidemiological studies and multi-site clinical trials as well as aspects of data collection, transfer, and analysis in these contexts. An advisory group will be asked to provide initial recommendations about the direction of the initiative and possible mechanisms for support. For further information contact: Dr. Susan Molchan or Dr. Neil Buckholtz at (301) 496-9350
The Immunology and Aging Workshop (advisory) is scheduled to be held June 13-14, 2002. The Purpose of This workshop is to present and discuss research advances in immunosenescence, gaps in our understanding of mechanisms responsible for decline in function of the immune system with age and areas that appear to be promising for increased research efforts. A discussion of strategies to recruit immunologists to these areas of research is also planned. The workshop is expected to promote interaction between researchers working in different areas of immunology and recommendations made by workshop participants will be included in a report of the meeting to be made available to NIA staff. (Contact: Dr. Rebecca Fuldner, BAP, 301-496-6402)
Ms. Georgeanne Patmios, returned to BSR as a Health Program Specialist, effective March 10, 2002. Ms. Patmios, who started her Government career in NIA/BSR in 1993, was reassigned to NIH, OBSSR (Office of Behavioral and Social Science Research) for the period November 2000 - March 2002. Ms. Patmios will serve as Acting Chief for the Population and Social Processes Branch. In addition, she will be responsible for tasks in the Office of the Associate Director in BSR including the Program's Inter-Agency Agreements.
Dr. Felipe Sierra joined the Biology of Aging Program on February 24, 2002. In his role as Health Scientist Administrator in BAP, he will administer and develop the Cell Structure and Function Program and the Protein Structure and Function Program. Most recently, Dr. Sierra was Associate Professor at the Insituto de Ciencias BiomJdicas, Facultad de Medicina, Universidad de Chile and Associate Investigator at the Lankenau Institute for Medical Research in Pennsylvania working with Dr. Vincent Cristofalo. Prior to that, he was Associate Professor at the Center for Gerontological Research, Allegheny University of the Health Sciences (later Medical College of Pennsylvania/Hahnemann University). Dr. Sierra has received several awards and grants including a NIA R01, Proteolysis and Aging: Effects on MAP Kinase Activity. He has served on the NIA-B Review Committee, as well as on ad-hoc review committees for the Biology of Aging Program. He was a member of the Board of Directors for the Sociedad Chileana de BiologRa (Chilean equivalent of FASEB) and in 1996 was awarded the Nathan Shock New Investigator Award for Excellence in Studies in Gerontology in the Biological Sciences.
Dr. Charles Hollingsworth has recently joined the National Institute on Aging as the Chief of the Clinical Trials Branch in the Geriatrics Program. Dr. Hollingsworth will direct the Program's clinical trials portfolio, including the current investigator-initiated clinical trials, as well as the Program's large, multicenter cooperative agreement studies, which are now in the process of either planning or initiation. Dr. Hollingsworth came to NIA from the National Center for Research Resources, where he was Director of the Office of Review. Dr. Hollingsworth received the M.S.H. in Biostatistics from the Graduate School of Public Health at the University of Pittsburgh, and the Dr. P.H. in Epidemiology from the School of Public Health at The University of Michigan. Dr. Hollingsworth has worked in industry and academia, and spent 14 years at the National Heart, Lung and Blood Institute as both a Program and Review Officer. His previous program duties at NHLBI were in the Cardiology Program of the Division of Heart and Vascular Diseases, and the Transfusion Medicine Program in the Division of Blood Diseases and Resources. Dr. Hollingsworth has been with NIH for over 20 years.
Tracy Cope will join the Office of Biological Resources and Resource Development (OBRRD) as a Biological Program Specialist on May 6, 2002. She will fill a new position created to assist in the management of the expanded resources developed and overseen by OBRRD. Ms. Cope has a B.A in Biology and has 14 years of experience as a laboratory technician at the Naval Medical Research Center in Silver Spring, MD. She has extensive experience in laboratory administration as well as hands on work with animal models. Ms. Cope will primarily assist in the human biospecimen repository initiative and in the management of NIA supported nonhuman primate resources, but will also provide support in tracking grants using stem cells.
The following publications are new or revised since the last Council meeting: Age Pages--Prostate Problems (update), Teeth and Mouth (update), Constipation (update), Depression (update), High Blood Pressure (update), and Arthritis (update); Talking With Your Doctor: A Guide for Older People (reprint); Alzheimer's Disease Center Program Directory (ADC Program Directory) (update); Connections (new issue focusing on frontotemporal dementia and tauopathies); AD Medications Fact Sheet (new); Alzheimer's Disease Thesaurus (update). For more information contact: Jane E. Shure, Director, OCPL, 301-496-1752.
To date more than 45,000 copies of El Ejercicio Y Su Salud, NIA's Spanish-language exercise guide, have been distributed through Hispanic senior centers, health centers, community centers, and churches, as well as appropriate government and national organizations. Spanish-language press releases distributed to the Hispanic print media resulted in stories in 42 publications and paid newspaper ads were placed in 8 markets including: Houston, San Diego, Albuquerque, Fresno, Sacramento, Denver, Washington, DC, and Boston. To promote the topic of exercise in general (and the guide in particular), Dr. David Espino, OCPL's expert spokesperson, conducted 20 radio interviews. In addition, radio public service announcements were played more than 11,000 times in 15 target States with an estimated listening audience of more than 30 million people. For more information contact: Jane E. Shure, Director, OCPL, 301-496-1752.
On March 19th, the new senior-friendly web site, http://nihseniorhealth.gov/, was opened for beta-testing. The web site is the result of a 2-year collaborative effort between NIA's OCPL and the National Library of Medicine (NLM). The website's researched-based design has been tailored to meet the cognitive and visual requirements of adults 60 and older. Currently, the site offers information on three aging-related health topics: Alzheimer's Disease, Caring for Someone with Alzheimer's Disease and Exercise for Older Adults. More topics are planned,. Focus group and usability testing has been conducted nationwide. A public kick-off event is planned for summer, 2002. For more information contact: Jane E. Shure, Director, OCPL, 301-496-1752.
Adults of all ages learned how the aging brain handles memory loss, depression, drugs, alcohol and more during Brain Awareness Week-- March 11 to March 15, 2002. NIA's OCPL coordinated 2 days of lectures entitled, "The Brain, The Body, and Aging." In addition, the NIA conducted hands-on computer workshops to show seniors how to find online health information. Brain Awareness Week began in 1995 by the Dana Alliance for Brain Initiatives, a non-profit organization whose commitment is to advance the public benefits of brain research. This year's celebration was coordinated by NIA. For more information contact: Jane E. Shure, Director, OCPL, 301-496-1752.
The following NIA-funded trials have been added to the clinical trials database: the Healthy Aging & Memory Study, sponsored by the Alzheimer's Disease Cooperative Study at UC San Diego and the Prevention of Alzheimer's Disease with Vitamin E and Selenium (PREADVISE) trial, an add-on to the NCI's SELECT study on preventing prostate cancer. For more information contact: Jane E. Shure, Director, OCPL, 301-496-1752.
The NIH Plain Language Committee recently presented OCPL's publication, Menopause-One Women's Story, Every Women's Story: A Resource for Making Healthy Choices an award for an outstanding publication in their annual plain language competition. For more information contact: Jane E. Shure, Director, OCPL, 301-496-1752.
From the NIH GUIDE - From January 8, 2002 - April 17, 2002Published since the last National Advisory Council on Aging Meeting.Also check our NIA website “Current Funding Opportunities”(Shown here are selected Notices relevant to NIA and selected Initiatives)
Revised PHS 2271 Now Available Release Date: April 5, 2002Notice: NOT-OD-02-042http://grants1.nih.gov/grants/guide/Notice-files/NOT-OD-02-042.htmlEffective Date: The revised "Statement of Appointment Form" (PHS 2271, Rev. 5/01) is now available and will be accepted immediately. For appointments beginning on or after June 1, 2002, the new form is required. Use of the previous version (Rev. 4/98) will be permitted for appointments that begin on or before May 31, 2002. Please note, the National Institutes of Health (NIH) must implement use of this revised form in order to maintain compliance with the Office of Management and Budget (OMB) standards for the collection of race/ethnicity data.
NIH Announces Statement on Certificates of Confidentiality Release Date: March 15, 2002Notice: NOT-OD-02-037http://grants1.nih.gov/grants/guide/Notice-files/NOT-OD-02-037.htmlCertificates of Confidentiality are issued by the National Institutes of Health (NIH) to protect identifiable research information from forced disclosure. They allow the investigator and others who have access to research records to refuse to disclose identifying information on research participants in any civil, criminal, administrative, legislative, or other proceeding, whether at thefederal, state, or local level.
Change of Receipt Dates: SBIR/STTR Grant Applications That Propose AIDS or AIDS-Related ResearchRelease Date: March 7, 2002Notice: NOT-OD-02-036http://grants1.nih.gov/grants/guide/Notice-files/NOT-OD-02-036.htmlSBIR and STTR grant applications that propose AIDS or AIDS-related research currently use the standard SBIR/STTR receipt dates of April 1, August 1, and December 1. All other investigator-initiated AIDS or AIDS-related research grant applications have receipt dates of May 1, September 1, and January 2. Effective with the publication of this announcement, the receipt dates for SBIR (R43 and R44) and STTR (R41 and R42) applications that propose AIDS or AIDS-related research will become the same as for all other AIDS applications: May 1, September 1, and January 2.
NIH Announces Draft Statement on Sharing Research DataRelease Date: March 1, 2002Notice: NOT-OD-02-035http://grants1.nih.gov/grants/guide/Notice-files/NOT-OD-02-035.htmlThe NIH is developing a statement on data sharing that expects and supports the timely release and sharing of final research data from NIH-supported studies for use by other researchers. Investigators submitting an NIH application will be required to include a plan for data sharing or to state why data sharing is not possible. This statement will apply to extramural scientists seeking grants, cooperative agreements, and contracts as well as intramural investigators.
Salary Limitation on Grants, Cooperative Agreements and Contracts Release Date: January 25, 2002(NOT-OD-02-030)http://grants1.nih.gov/grants/guide/Notice-files/NOT-OD-02-030.htmlThe Purpose of This Notice is to provide updated information regarding the salary limitation as it relates to NIH grant and cooperative agreement awards. This information also applies to extramural research and development contract awards.
National Research Service Award (NRSA) Stipend Increase and Other Budgetary Changes Effective For Fiscal Year 2002Release Date: January 22, 2002(NOT-OD-02-028)http://grants1.nih.gov/grants/guide/Notice-files/NOT-OD-02-028.htmlAgency for Healthcare Research and QualityHealth Resources Services AdministrationThe budgetary changes described here for fiscal Year 2002 NRSA awards affect the stipend levels for predoctoral and postdoctoral trainees and fellows. In addition, the Training Related Expenses for trainees and the Institutional Allowance for individual fellows has been increased.
NIH Extramural Loan Repayment Program Regarding Clinical ResearchersRelease Date: January 8, 2002Notice: NOT-OD-02-024http://grants1.nih.gov/grants/guide/Notice-files/NOT-OD-02-024.htmlThe Purpose of This Program is the recruitment and retention of highly qualified health professionals as clinical investigators. Through this Notice, the NIH invites qualified health professionals who contractually agree to engage in clinical research as extramural grantees or awardees for at least two years, to apply for participation in the NIH Loan Repayment Program for Clinical Researchers.
Alzheimer's Disease Clinical Research and Training Program: Mentored Scientist Development Awards (K08 and K01)Release Date: April 17, 2002RFA: AG-02-006http://grants1.nih.gov/grants/guide/rfa-files/RFA-AG-02-006.htmlProgram Participating: Neuroscience and Neuropsychology ProgramApplication Receipt Date: July 16, 2002Purpose of This PA These mechanisms provide support for a period of supervised research and study for either clinically trained professionals with little research experience but who have the commitment and the potential to develop into productive, independent Alzheimer's disease investigators (K08) or for clinically trained professionals with substantial research experience who wish to redirect their career to concentrate on Alzheimer's research (K01).Direct your questions about scientific/research issues to:Elisabeth Koss, Ph.D.Neuroscience and Neuropsychology of Aging ProgramNational Institute on Aging7201 Wisconsin Ave., Suite 3C307Bethesda, MD 20892-9205Telephone: (301) 496-9350FAX: (301) 496-1494Email: kosse@nia.nih.gov
Innovation Grants for Research On Hutchinson-Gilford Progeria Syndrome (U01)Release Date: April 10, 2002PA Number: PAR-02-097http://grants1.nih.gov/grants/guide/pa-files/PAR-02-097.htmlProgram Participating: Biology of Aging ProgramApplication Receipt Date: Standard NIH Receipt Dates http://grants1.nih.gov/grants/funding/submissionschedule.htmPurpose of This PAThis Program Announcement (PA) is a new initiative to support research on the mechanistic basis of Hutchinson-Gilford progeria syndrome (HGPS). This syndrome has some features typical of normal human aging, and is thus often referred to as a premature aging syndrome.Direct your questions about scientific/research issues to:Huber R. Warner, Ph.D., Associate DirectorBiology of Aging ProgramNational Institute on Aging7201 Wisconsin AvenueGateway Building, Suite 2C231Bethesda, MD 20892TEL: 301/496-4996FAX: 301/402-0010Email: warnerh@nia.nih.gov
Aging Intervention Testing Program (U01)Release Date: April 9, 2002RFA: AG-02-005http://grants1.nih.gov/grants/guide/rfa-files/RFA-AG-02-005.htmlProgram Participating: Biology of Aging ProgramApplication Receipt Date: September 12, 2002Purpose of This RFAThe main Purpose of This program is to test, under standardized conditions in multiple sites, potential intervention strategies which may decelerate the rate of aging in mammals.Direct your questions about scientific/research issues to:Huber R. Warner, Ph.D., Associate DirectorBiology of Aging ProgramNational Institute on Aging7201 Wisconsin AvenueGateway Building, Suite 2C231Bethesda, MD 20892TEL: 301/496-4996FAX: 301/402-0010Email: warnerh@nia.nih.gov
Centers for Population Health and Health Disparities (P50)Release Date: April 1, 2002RFA: ES-02-009http://grants1.nih.gov/grants/guide/rfa-files/RFA-ES-02-009.htmlProgram Participating: Behavioral and Social Research ProgramApplication Receipt Date: August 29, 2002Purpose of This PA Applicants are invited to propose multi-level, integrated research projects that will elucidate the complex interactions of the social and physical environment, mediating behavioral factors, and biologic pathways which determine health and disease.Direct your questions about scientific/research issues to:Georgeanne E. Patmios, M.A.National Institute on AgingBehavioral and Social Research Program7201 Wisconsin AvenueGateway Building, Suite 533Bethesda, MD 20892-7936Bethesda, MD 20892-7936Telephone: (301) 496-3138FAX: (301) 402-0051 Email: patmios@nih.gov
Androgen Receptor in Prostate Growth and Cancer (R01, R21)Release Date: April 1, 2002RFA: DK-02-031http://grants1.nih.gov/grants/guide/rfa-files/RFA-DK-02-031.htmlProgram Participating: Biology of Aging ProgramApplication Receipt Date: November 14, 2002Purpose of This RFA This RFA seeks applications that will foster greater understanding of the role of the androgen receptor (AR) in carrying out the signaling program that reflects androgen action in the prostate gland.Direct your questions about scientific/research issues relevant to NIA to:Frank Bellino, Ph.D.Biology of Aging ProgramNational Institute on Aging7201 Wisconsin Avenue, Suite 2C231 MSC 9205Bethesda, MD 20892-9205Telephone: (301) 496-6402FAX: (301) 402-0010Email: fb12a@nih.gov
Large-Scale Genotyping for the Haplotype Map of the Human Genome (U54)Release Date: March 26, 2002RFA: HG-02-005http://grants1.nih.gov/grants/guide/rfa-files/RFA-HG-02-005.htmlProgram Participating: Biology of Aging ProgramApplication Receipt Date; May 29, 2002.Purpose of This RFA This is a joint initiative among several Institutes and Centers at NIH to develop a haplotype map of the human genome. This RFA solicits cooperative agreement applications for the large-scale genotyping across the genome of samples from three populations.Direct your questions about scientific/research issues to:Anna McCormick, Ph.D.National Institute on Aging Gateway Building, Suite 2C231Bethesda, MD 20892-9205Telephone: (301) 496-6402Email: mccormia@nia.nih.gov
Mentored Clinical Scientists Development Program Award (K12 AWARD)Release Date: March 11, 2002PA Number: PAR-02-076http://grants1.nih.gov/grants/guide/pa-files/PAR-02-076.htmlProgram Participating: All ProgramsApplication Receipt Date: Standard NIH Receipt Dates http://grants1.nih.gov/grants/funding/submissionschedule.htmPurpose of This PAThis PA replaces, in its entirety, the Mentored Clinical Scientist Development Program Award (MCSDPA), PA-95-054, published in the NIH Guide for Grants and Contracts, Volume 24, Number 15, April 28, 1995. This MCSDPA is an award to an educational institution or professional organization to support career development experiences for clinicians leading to research independence. Direct your questions about scientific/research issues to:Dr. Robin A. BarrOffice of Extramural AffairsNational Institute on Aging7201 Wisconsin Avenue, Room 2C218, MSC 9205Bethesda, MD 20892-9205Telephone: (301) 496-9322Email: rb42h@nih.gov
Methodology and Measurement in the Behavioral and Social Sciences Release Date: March 7, 2002PA Number: PA-02-072http://grants1.nih.gov/grants/guide/pa-files/PA-02-072.htmlProgram Participating: Behavioral and Social Research ProgramApplication Receipt Date: Standard NIH Receipt Dates http://grants1.nih.gov/grants/funding/submissionschedule.htmPurpose of This PAThe goal of this program announcement is to encourage research that will improve the quality and scientific power of data collected in the behavioral and social sciences, relevant to the missions of the NIH Institutes and Centers.Direct your questions about scientific/research issues to:Sidney Stahl, Ph.D.Behavioral and Social Research ProgramGateway Building, Room 5337201 Wisconsin AvenueBethesda, MD 20892-9205Telephone: (301) 402-4156Fax: (301) 402-0051E-mail: Stahls@nia.nih.gov
Basic Research on Mesenchymal Stem Cell Biology (R01)Release Date: March 6, 2002RFA: HL-02-018http://grants1.nih.gov/grants/guide/rfa-files/RFA-HL-02-018.htmlProgram Participating: Biology of Aging ProgramApplication Receipt Date: June 20, 2002Purpose of This RFA Preclinical studies suggest mesenchymal stem cells facilitate hematopoietic stem cell transplantation while decreasing immune rejection of allogeneic transplants.Direct your questions about scientific/research issues to: Dr. Jill L. CarringtonBiology of Aging ProgramNational Institute on Aging7201 Wisconsin Avenue Suite 2C231Bethesda, MD 20892Telephone: (301) 496-6402FAX: (301) 402-0010Email: CarringtonJ@nia.nih.gov
Human Subjects Research Enhancements Program RFA: OD-02-003 Release Date: March 5, 2002http://grants1.nih.gov/grants/guide/rfa-files/RFA-OD-02-003.htmlProgram Participating: All ProgramsApplication Receipt Date: May 7, 2002Purpose of This RFA The Purpose of This initiative is to provide short-term interim support for institutional activities that will strengthen oversight of human subjects research at institutions that receive significant NIH support for clinical research.Direct your questions about scientific/research issues to:Miriam F. Kelty, Ph.D.Associate Director, Office of Extramural Affairs7201 Wisconsin Avenue, Suite 2C218Bethesda, MD 20892-9205Telephone: (301) 496-9322FAX: (301) 402-2945Email: rb42h@nih.govWeb site: http://www.nih.gov/nia/
Innovative Technologies for Enhancing Function for Individuals With Disabilities Release Date: March 4, 2002PA Number: PA-02-071http://grants1.nih.gov/grants/guide/pa-files/PA-02-071.htmlProgram Participating: Behavioral and Social Research ProgramApplication Receipt Date: Standard NIH Receipt Dates http://grants1.nih.gov/grants/funding/submissionschedule.htmPurpose of This PAThis Program Announcement (PA) is to encourage small businesses to participate in assistive technology research that facilitates the rehabilitation of individuals with disabilities resulting from injury and disease.Direct your questions about scientific/research issues to:Sidney M. Stahl, Ph.D.National Institute on AgingNational Institutes of HealthGateway Building, Room 5337201 Wisconsin AvenueBethesda, MD 20892-9205Telephone: (301) 402-4156Fax: (301) 402-0051E-mail: StahlS@nia.nih.gov
Structural Biology of Membrane Proteins Release Date: February 11, 2002PA Number: PA-02-060http://grants1.nih.gov/grants/guide/pa-files/PA-02-060.htmlProgram Participating: Neuroscience and Neuropsychology ProgramApplication Receipt Date: Standard NIH Receipt Dates http://grants1.nih.gov/grants/funding/submissionschedule.htmPurpose of This PAThe Purpose of This program announcement (PA) is to encourage basic research on the structures of membrane proteins at atomic resolution. It replaces and updates previous program announcements (PA-99-004 and PA-95-035), which were issued under the same title. Direct your questions about scientific/research issues to:Bradley C. Wise, Ph.D.Program Director, Fundamental NeuroscienceNeuroscience and Neuropsychology of Aging ProgramNational Institute on Aging7201 Wisconsin Avenue, Suite 3C307 MSC 9205Bethesda, MD 20892-9205Telephone: (301) 496-9350FAX: (301) 496-1494Email: wiseb@nia.nih.gov
Short-Term Courses in Human Embryonic Stem Cell Culture Techniques (T15)Release Date: February 1, 2002PA Number: PA-02-054http://grants1.nih.gov/grants/guide/pa-files/PA-02-054.htmlProgram Participating: Biology of Aging ProgramApplication Receipt DateS: April 23, 2002 and October 23, 2002Purpose of This PAThe National Institutes of Health (NIH) invites applications for grants to develop, conduct, evaluate, and disseminate short-term courses on laboratory research techniques for human embryonic stem cell lines.Direct your questions about scientific/research issues to:Jill L. Carrington, Ph.D.Chief, Systems Branch; Director, Musculoskeletal BiologyBiology of Aging ProgramNational Institute on AgingTelephone: (301) 496-6402FAX: (301) 402-0010E-mail: carringtonj@nia.nih.gov
Global Health Research Initiative Program for New Foreign Investigators (R01)Release Date: January 29, 2002RFA-TW-02-002http://grants1.nih.gov/grants/guide/rfa-files/RFA-TW-02-002.htmlProgram Participating: All ProgramsApplication Receipt Date: April 19, 2002.Purpose of This RFA This RFA is intended to promote productive re-entry of NIH-trained foreign investigators into their home countries as part of a broader program to enhance the scientific research infrastructure in developing countries.Direct your questions about scientific/research issues to:Marta Campbell Welsh, ChiefOffice of International ActivitiesNational Institute on AgingGateway Building, Suite 2C2277201 Wisconsin Avenue MSC 9205Bethesda, MD 20892-9205Phone: (301) 496-0767Fax : (301) 402-0260Email:WelshM@nia.nih.gov
NIA Pilot Research Grant Program (R03)Release Date: January 24, 2002PA Number: PAR-02-049http://grants1.nih.gov/grants/guide/pa-files/PAR-02-049.htmlProgram Participating: All ProgramsApplication Receipt DateS: March 15, 2002, July 15, 2002, November 15, 2002Purpose of This PAThis initiative seeks small grant (R03) applications in specific areas to: (1) stimulate and facilitate the entry of promising new investigators into aging research, and (2) encourage established investigators to enter new targeted, high priority areas in this research field.Direct your questions about scientific/research issues to:Robin A. Barr, Ph.D.Deputy Associate DirectorOffice of Extramural Affairs7201 Wisconsin Avenue, Suite 2C218Bethesda, MD 20892-9205Telephone: (301) 496-9322FAX: (301) 402-2945Email: rb42h@nih.govWeb site: http://www.nih.gov/nia/
Dissertation Research Grants for Underrepresented Minorities in The Ethical, Legal, and Social Implications (ELSI) of Genetics Research (R03)Release Date: January 22, 2002PA Number: PA-02-048http://grants1.nih.gov/grants/guide/pa-files/PA-02-048.html Program Participating: Behavioral and Social Research ProgramApplication Receipt Date: Standard NIH Receipt Dates http://grants1.nih.gov/grants/funding/submissionschedule.htmPurpose of This PAThe Purpose of This program announcement (PA) is to stimulate and encourage underrepresented minority doctoral candidates from a variety of academic disciplines and programs (See Individuals Eligible to Become Principal Investigators) to conduct research related to the ethical, legal, and social implications (ELSI) of genetics, genomics, and gene-environment interaction research.Direct your questions about scientific/research issues to:Jennifer Harris, Ph.D.Behavioral and Social Research ProgramNational Institute on Aging7201 Wisconsin AvenueSuite 533, MSC 9205Bethesda, MD 20892-9205TEL: (301) 496-3138FAX: (301) 402-0051Email: jh475o@nih.gov
As presented in the FY 2003 Congretional JustificationDate: 04/05/02
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