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Selected Publications

Fluorescence Microscopy & Imaging Center

Below is a list of all publications that included data acquired and/or analyzed via the NIEHS Fluorescence Microscopy & Imaging Center, up through the end of 2005. It is organized reverse chronologically, and alphabetized within each year according to first author. If you notice any errors or omissions, please notify the Center.


  1. Daniel A. J. Bow, Jennifer L. Perry, John D. Simon, and John B. Pritchard. The impact of plasma protein binding on the renal transport of organic anions. J Pharmacol Exp Ther. 2006 Jan; 316(1):349-55. Epub 2005 Sep 29
  2. Heping Cao, Leesa J. Deterding, John D. Venable, Elizabeth A. Kennington, John R. Yates III, Kenneth B. Tomer and Perry J. Blackshear. Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis. Biochem J. [Epub 2005 Nov 1 ahead of print]
  3. Anika M.S. Hartz, Björn Bauer, Gert Fricker and David S. Miller. Rapid Modulation of P-glycoprotein-Mediated Transport at the Blood-Brain Barrier by TNF-α and LPS. Mol Pharmacol. [Epub 2005 Nov 8 ahead of print]
  4. Gerd Heimlich, and John A. Cidlowski. Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells. J Biol Chem. [Epub 2005 Nov 18 ahead of print]
  5. Fardin Hosseinpour, Rick Moore, Masahiko Negishi, Tatsuya Sueyoshi. Serine-202 regulates the nuclear translocation of constitutive active/androstane receptor CAR. Mol Pharmacol. [Epub 2005 Dec 23 ahead of print]
  6. Gregory R. Stuart, Janine H. Santos, Micheline K. Strand, Bennett Van Houten and William C. Copeland. Mitochondrial and Nuclear DNA Defects in Saccharomyces cerevisiae With Mutations in DNA Polymerase γ Associated With Progressive External Ophthalmoplegia. Hum Mol Genet. [Epub2005 Dec 20 ahead of print]
  7. Ling Yang, Jeff Reece, Sherif E. Gabriel, and Stephen B. Shears. Apical localization of ITPK1 enhances its ability to be a modifier gene product in a murine tracheal cell model of cystic fibrosis. J Cell Sci. [in press]


  1. Boyko S. Atanassov, J. Carl Barrett, and Barbara J. Davis. Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2-Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links' repair but does not affect meiosis. Genes Chromosomes Cancer 44(4):429-37
  2. Bjorn Bauer, Anika M. S. Hartz, Gert Fricker, and David S. Miller. Modulation of p-glycoprotein transport function at the blood-brain barrier. Exp Biol Med 230: 118-127
  3. Tomokazu Fukuda, Yuji Mishina, Michael P. Walker, and Richard P. DiAugustine. Conditional transgenic system for mouse aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein. Mol Cell Biol. 25(12):5270-81
  4. Seong-Chul Kim, Yong-Sik Kim and Anton M. Jetten. Krüppel-like zinc finger protein Gli-similar 2 (Glis2) represses transcription through interaction with C-terminal binding protein 1 (CtBP1). Nucleic Acids Res: 33(21):6805-15
  5. Nick Z. Lu and John A. Cidlowski. Translational Regulatory Mechanisms Generate N-Terminal Glucocorticoid Receptor Isoforms with Unique Transcriptional Target Genes. Mol Cell: 18(3):331-42
  6. Wei Qu, Bhalchandra A. Diwan, Jeffrey M. Reece, Carl D. Bortner, Jingbo Pi, Jie Liu and Michael P. Waalkes. Cadmium-induced malignant transformation in rat liver cells: role of aberrant oncogene expression and minimal role of oxidative stress. Int J Cancer: 114(3):346-55
  7. Marcel J.M. Schaaf, Laura J. Lewis-Tuffin and John A. Cidlowski. Ligand-selective targeting of the glucocorticoid receptor to nuclear subdomains is associated with decreased receptor mobility. Mol Endocrinol: 19(6):1501-15
  8. Mohamed Trebak, Nadine Hempel, Barbara J. Wedel, Jeremy T. Smyth, Gary St. J. Bird, and James W. Putney, Jr. Negative Regulation of TRPC3 Channels by Protein Kinase CMediated Phosphorylation of Serine 712. Mol Pharmacol: 67(2):558-63
  9. Tongguang Wang, Zhong Pei, Wei Zhang, Bin Liu, Robert Langenbach, Christopher Lee, Belinda Wilson, Jeffrey M. Reece, David S. Miller, and Jau-Shyong Hong. MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration. FASEB J: 19(9):1134-6
  10. Wei Zhang, Tongguang Wang, Zhong Pei, David S. Miller, Xuefei Wu3, Michelle L. Block, Belinda Wilson, Wanqin. Zhang, Yong Zhou, Jau-Shyong Hong, and Jing Zhang Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease. FASEB J: 19(6):533-42

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  1. Bjorn Bauer, Anika M. S. Hartz, Gert Fricker, and David S. Miller. Pregnane X receptor up-regulation of p-glycoprotein expression and transport function at the blood-brain barrier. Mol Pharmacol 66: 413-419
  2. Sukhdev S. Brar, Mary Watson, and Marilyn Diaz. Activation-induced cytosine deaminase (AID) is actively exported out of the nucleus but retained by the induction of DNA breaks. J Biol Chem 279: 26395-26401
  3. Christopher M. Breen, Destiny B. Sykes, Carsten Baehr, Gert Fricker, and David S. Miller. Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy. Am J Physiol Renal Physiol 287: F562-F569
  4. Heping Cao. Expression, purification, and biochemical characterization of the antiinflammatory tristetraprolin: A zinc-dependent mRNA binding protein affected by posttranslational modifications. Biochemistry 43 13724–13738
  5. Heping Cao, Jane S. Tuttle, and Perry J. Blackshear. Immunological characterization of tristetraprolin as a low abundance, inducible, stable cytosolic protein. J Biol Chem 279: 21489-21499
  6. Maximiliano A. D'Angelo, Santiago Sanguineti, Jeffrey M. Reece, Lutz Birnbaumer, Héctor N. Torres and Mirtha M. Flawiá. Identification, characterization and subcellular localization of TcPDE1, a novel cAMP-specific phosphodiesterase from Trypanosoma cruzi. Biochem J 378: 63-72
  7. Yaron Daniely, Grace Liao, Darlene Dixon, R. Ilona Linnoila, Adriana Lori, Scott H. Randell, Moshe Oren, and Anton M. Jetten. Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am J Physiol Cell Physiol 287: C171-C181
  8. Anika M. S. Hartz, Bjorn Bauer, Gert Fricker, and David S. Miller. Rapid regulation of p-glycoprotein at the blood-brain barrier by endothelin-1. Mol Pharmacol 66: 387-394
  9. Yu-Ying He, Jian-Li Huang, and Colin F. Chignell. Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: Implications in carcinogenesis. J Biol Chem 279: 53867-53874
  10. Yong-Sik Kim, Gen Nakanishi, Asa J. Oudes, Kwan Hee Kim, Hang Wang, Daniel L. Kilpatrick, and Anton M. Jetten. Tsp57: A Novel Gene Induced During a Specific Stage of Spermatogenesis. Biol Reprod: 70(1):106-13
  11. David S. Miller. Confocal imaging of xenobiotic transport across the choroid plexus. Adv Drug Deliv Rev 56: 1811-1824
  12. Takeshi Nakajima, Sanae Fujino, Gen Nakanishi, Yong-Sik Kim, and Anton M. Jetten. TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4. Nucl Acids Res 32: 4194-4204
  13. Wei Qu, Bhalchandra A. Diwan, Jeffrey M. Reece, Carl D. Bortner, Jingbo Pi, Jie Liu, and Michael P. Waalkes. Cadmium-induced malignant transformation in rat liver cells: Role of aberrant oncogene expression and minimal role of oxidative stress. Int J Cancer 114: 346-355
  14. Silvia B. V. Ramos, Deborah J. Stumpo, Elizabeth A. Kennington, Ruth S. Phillips, Cheryl B. Bock, Fernando Ribeiro-Neto, and Perry J. Blackshear. The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development. Development 131: 4883-4893
  15. Fernando Ribeiro-Neto, Angelica Leon, Julie Urbani-Brocard, Liguang Lou, Abraham Nyska, and Daniel L. Altschuler. cAMP-dependent oncogenic action of Rap1b in the thyroid gland. J Biol Chem. 2004 Nov 5;279(45):46868-75
  16. Janine Hertzog Santos, Joel N. Meyer, Milan Skorvaga, Lois A. Annab and Bennett Van Houten. Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. Aging Cell. 2004 Dec;3(6):399-411
  17. John Seubert, Baichun Yang, J. Alyce Bradbury, Joan Graves, Laura M. Degraff, Scott Gabel, Rebecca Gooch, Julie Foley, John Newman, Lan Mao, Howard A. Rockman, Bruce D. Hammock, Elizabeth Murphy, and Darryl C. Zeldin. Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circ Res 95: 506-514
  18. E. James Squires, Tatsuya Sueyoshi, and Masahiko Negishi. Cytoplasmic localization of pregnane X receptor and ligand-dependent nuclear translocation in mouse liver. J Biol Chem 279: 49307-49314
  19. Deborah J. Stumpo, Noah A. Byrd, Ruth S. Phillips, Sanjukta Ghosh, Robert R. Maronpot, Trisha Castranio, Erik N. Meyers, Yuji Mishina, and Perry J. Blackshear. Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the tristetraprolin family. Mol Cell Biol 24: 6445-6455
  20. Destiny Sykes, Douglas H. Sweet, Simon Lowes, Sanjay K. Nigam, John B. Pritchard, and David S. Miller. Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice. Am J Physiol Renal Physiol 286: F972-F978
  21. Hongbing Wang, Stephanie Faucette, Rick Moore, Tatsuya Sueyoshi, Masahiko Negishi, and Edward LeCluyse. Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin. J Biol Chem 279: 29295-29301


  1. Carl D. Bortner, and John A. Cidlowski. Uncoupling cell shrinkage from apoptosis reveals that Na+ influx is required for volume loss during programmed cell death. J Biol Chem 278: 39176-39184
  2. Marilyn Diaz, Madhumita Ray, Linda J. Wheeler, Laurent K. Verkoczy and Christopher K. Mathews. Mutagenesis by AID, a molecule critical to immunoglobulin hypermutation, is not caused by an alteration of the precursor nucleotide pool. Mol Immun 40: 261-268
  3. Maria Gómez-Angelats and John A. Cidlowski. Molecular evidence for the nuclear localization of FADD. Cell Death Differ: 10(7):791-7
  4. Yu-Ying He, Jian-Li Huang, Jennifer B. Gentry, and Colin F. Chignell. Epidermal growth factor receptor down-regulation induced by UVA in human keratinocytes does not require the receptor kinase activity. J Biol Chem 278: 42457-42465
  5. Yong-Sik Kim, Gen Nakanishi, Mark Lewandoski, and Anton M. Jetten. GLIS3, a novel member of the GLIS subfamily of Kruppel-like zinc finger proteins with repressor and activation functions. Nucl Acids Res 31: 5513-5525
  6. Kaoru Kobayashi, Tatsuya Sueyoshi, Kaoru Inoue, Rick Moore, and Masahiko Negishi. Cytoplasmic accumulation of the nuclear receptor CAR by a tetratricopeptide repeat protein in HepG2 cells. Mol Pharmacol 64: 1069-1075
  7. Dianxin Liu, Xin Wang, Zhiping Zhang and Christina T. Teng. An intronic alternative promoter of the human lactoferrin gene is activated by Ets. Biochem Biophys Res Commun 301: 472-479
  8. David S. Miller. Confocal imaging of xenobiotic transport across the blood-brain barrier. J Exp Zoolog A Comp Exp Biol 300: 84-90
  9. Robert P. Mohney, Margaret Das, Trever G. Bivona, Richard Hanes, Anthony G. Adams, Mark R. Philips, and John P. O'Bryan. Intersectin activates ras but stimulates transcription through an independent pathway involving JNK. J Biol Chem 278: 47038-47045
  10. Jingbo Pi, Wei Qu, Jeffrey M. Reece, Yoshito Kumagai and Michael P. Waalkes. Transcription factor Nrf2 activation by inorganic arsenic in cultured keratinocytes: involvement of hydrogen peroxide. Exp Cell Res 290: 234-245
  11. Marcel J. M. Schaaf, and John A. Cidlowski. Molecular determinants of glucocorticoid receptor mobility in living cells: the importance of ligand affinity. Mol Cell Biol 23: 1922-1934
  12. Carol S. Trempus, Rebecca J. Morris, Carl D. Bortner, George Cotsarelis, Randall S. Faircloth, Jeffrey M. Reece, and Raymond W. Tennant. Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34. J Invest Dermatol 120: 501-511
  13. Barbara J. Wedel, Guillermo Vazquez, Richard R. McKay, Gary St. J. Bird, and James W. Putney, Jr. A Calmodulin/Inositol 1,4,5-Trisphosphate (IP3) Receptor-binding Region Targets TRPC3 to the Plasma Membrane in a Calmodulin/IP3 Receptor-independent Process. J Biol Chem 278(28): 25758-65
  14. Matthew R. Yudt, Christine M. Jewell, Rachelle J. Bienstock, and John A. Cidlowski. Molecular origins for the dominant negative function of human glucocorticoid receptor beta. Mol Cell Biol 23: 4319-4330

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  1. Christopher M. Breen, Destiny B. Sykes, Gert Fricker, and David S. Miller. Confocal imaging of organic anion transport in intact rat choroid plexus. Am J Physiol Renal Physiol 282: F877-F885
  2. Evelyne Dubois, Bart Scherens, Fabienne Vierendeels, Melisa M. W. Ho, Francine Messenguy, and Stephen B. Shears. In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis. J Biol Chem 277: 23755-23763
  3. Christian Erxleben, Angela L. Everhart, Charles Romeo, Hannah Florance, Mary Beth Bauer, David A. Alcorta, Sandra Rossie, Michael J. Shipston, and David L. Armstrong. Interacting effects of N-terminal variation and strex exon splicing on slo potassium channel regulation by calcium, phosphorylation, and oxidation. J Biol Chem 277: 27045-27052
  4. Hui-Ming Gao, Janwei Jiang, Belinda Wilson, Wanqin Zhang, Jau-Shyong Hong, and Bin Liu. Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson’s disease. J Neurochem 81: 1285–1297
  5. Yong-Sik Kim, Mark Lewandoski, Alan O. Perantoni, Shogo Kurebayashi, Gen Nakanishi, and Anton M. Jetten. Identification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functions. J Biol Chem 277: 30901-30913
  6. David S. Miller, Claudia Graeff, Lucy Droulle, Stefanie Fricker, and Gert Fricker. Xenobiotic efflux pumps in isolated fish brain capillaries. Am J Physiol Regul Integr Comp Physiol 262: R191-R198
  7. Ruth S. Phillips, Silvia B. V. Ramos, and Perry J. Blackshear. Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling. J Biol Chem 277: 11606-11613
  8. Fernando Ribeiro-Neto, Julie Urbani, Nicolas Lemee, Liguang Lou, and Daniel L. Altschuler. On the mitogenic properties of Rap1b: cAMP-induced G1S entry requires activated and phosphorylated Rap1b. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5418-23
  9. Joan E. Roberts, Barbara M. Kukielczak, Dan-Ning Hu, David S. Miller, Piotr Bilski, Robert H. Sik, Ann G. Motten, and Colin F. Chignell. The role of A2E in prevention or enhancement of light damage in human retinal pigment epithelial cells. Photochem Photobiol 75: 184-190
  10. Douglas H. Sweet, David S. Miller, John B. Pritchard, Yuko Fujiwara, David R. Beier, and Sanjay K. Nigam. Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. J Biol Chem 277: 26934-26943
  11. Tatsuya Sueyoshi, Rickie Moore, Jean M. G. Pascussi, and Masahiko Negishi. Direct expression of fluorescent protein-tagged nuclear receptor CAR in mouse liver. Methods Enzymol 357: 205-213
  12. Guillermo Vazquez, Barbara J. Wedel, Gary St. J. Bird, S. K. Joseph, and James W. Putney Jr. An inositol 1,4,5-triphosphate receptor-dependent cation entry pathway in DT40 B lymphocytes. EMBO J 21: 4531-4538
  13. Alice R. A. Villalobos, David S. Miller, and J. Larry Renfro. Transepithelial organic anion transport by shark choroid plexus. Am J Physiol Regul Integr Comp Physiol 282: R1308-R1316
  14. Zhijiang Yan, Yong-Sik Kim, and Anton M. Jetten. RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor. J Biol Chem 277: 32379-32388
  15. Feng Zhang, Gen Nakanishi, Shogo Kurebayashi, Kiyoshi Yoshino, Alan Perantoni, Yong-Sik Kim, and Anton M. Jetten. Characterization of Glis2, a novel gene encoding a Gli-related, Krüppel-like transcription factor expressed predominantly in kidney. Identification of transactivation and repressor functions. J Biol Chem 277: 10139-10149


  1. J. J. Inbaraj, B. M. Kukielczak, P. Bilski, S. L. Sandvik, and C. F. Chignell. Photochemistry and photocytotoxicity of berberine alkaloids from Goldenseal (Hydrastis canadensis L.) 1. Berberine. Chem Res Toxicol 14: 1529-1534
  2. David S. Miller. Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule. J Pharmacol Exp Therap 299: 567-574
  3. Gwendolyn Spizz and Perry J. Blackshear. Overexpression of the myristoylated alanine-rich C-kinase substrate inhibits cell adhesion to extracellular matrix components. J Biol Chem 76: 32264-32273
  4. Douglas H. Sweet, David S. Miller, and John B. Pritchard. Ventricular choline transport: A role for organic cation transporter 2 expressed in choroid plexus. J Biol Chem 276: 41611-41619
  5. John D. Whittard and Steven K. Akiyama. Positive regulation of cell-cell and cell-substrate adhesion by protein kinase. A J Cell Sci 114: 3265-3272
  6. John D. Whittard and Steven K. Akiyama. Activation of b1 integrins induces cell-cell adhesion. Exp Cell Res 263: 65-76
  7. Baichun Yang, LeRae Graham, Serguei Dikalov, Ronald P. Mason, John R. Falck, James K. Liao, and Darryl C. Zeldin. Overexpression of cytochrome P450 CYP2J2 protects against hypoxia-reoxygenation injury in cultured bovine aortic endothelial cells. Mol Pharm 60: 310-320


  1. Rosalinde Masereeuw, Sylvie A. Terlouw, Rémon A. M. H. van Aubel, Frans G. M. Russel, and David S. Miller. Endothelin B receptor-mediated regulation of ATP-driven drug secretion in renal proximal tubule. Mol Pharmacol 57: 59-67
  2. Richard R. McKay, Caroline L. Szymeczek-Seay, Jean-Philippe Lievremont, Gary St. J. Bird, Christof Zitt, Eberhard Jüngling, Andreas Lückhoff and James W. Putney, Jr. Cloning and expression of the human transient receptor potential 4 (TRP4) gene: localization and functional expression of human TRP4 and TRP3. Biochem J 351: 735-746
  3. David S. Miller, Stephanie N. Nobmann, Heike Gutmann, Michael Toeroek, Juergen Drewe, and Gert Fricker. Xenobiotic transport across isolated brain microvessels studied by confocal microscopy. Mol Pharmacol 58: 1357-1367
  4. Carla M. Pedrosa Ribeiro, Richard R. McKay, Eiji Hosoki, Gary St. J. Bird and James W. Putney Jr. Effects of elevated cytoplasmic calcium and protein kinase C on endoplasmic reticulum structure and function in HEK293 cells. Cell Calcium 27: 175-185
  5. Alyson B. Scoltock, Carl D. Bortner, Gary St. J. Bird, James W. Putney, Jr., and John A. Cidlowski. A selective requirement for elevated calcium in DNA degradation, but not early events in anti-Fas-induced apoptosis. J Biol Chem 275: 30586-30596
  6. Douglas H. Sweet, David S. Miller, and John B. Pritchard. Basolateral localization of organic cation transporter 2 in intact renal proximal tubules. Am J Physiol Renal Physiol 279: F826-F834

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  1. Gary St. J. Bird, Masaaki Takahashi, Kazuhiko Tanzawa, and James W. Putney Jr. Adenophostin A induces spatially restricted calcium signaling in Xenopus laevis oocytes. J Biol Chem 274: 20643-20649
  2. Wi S. Lai, Ester Carballo, Julie R. Strum, Elizabeth A. Kennington, Ruth S. Phillips, and Perry J. Blackshear. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol Cell Biol 19: 4311-4323
  3. David S. Miller, Alice R. Villalobos, and John B. Pritchard. Organic cation transport in rat choroid plexus cells studied by fluorescence microscopy. Am J Physiol Cell Physiol 276: C955-C968
  4. John B. Pritchard, Douglas H. Sweet, David S. Miller, and Ramsey Walden. Mechanism of organic anion transport across the apical membrane of choroid plexus. J Biol Chem 274: 33382-33387
  5. Huiping Shi, Zhiping Zhang, Xin Wang, Shiguang Liu, Christina T. Teng. Isolation and characterization of a gene encoding human Kruppel-like factor 5 (IKLF): binding to the CAAT/GT box of the mouse lactoferrin gene promoter. Nucl Acids Res 27: 4807-4815
  6. Douglas H. Sweet, David S. Miller, and John B. Pritchard. Localization of an organic anion transporter-GFP fusion construct (rROAT1-GFP) in intact proximal tubules. Am J Physiol Renal Physiol 276: F864-F873
  7. Douglas H. Sweet, David S. Miller, and John B. Pritchard. Localization of an organic anion transporter-GFP fusion construct (rROAT1-GFP) in intact proximal tubules. Am J Physiol 276: F864-F873


  1. David S. Miller. Protein kinase C regulation of organic anion transport in renal proximal tubule. Am J Physiol 274: F156-F164
  2. David S. Miller, Rosalinde Masereeuw, John Henson, and Karl J. Karnaky, Jr. Excretory transport of xenobiotics by dogfish shark rectal gland tubules. Am J Physiol 274: R697-705
  3. David S. Miller, Caroline R. Sussman, and J. Larry Renfro. Protein kinase C regulation of p-glycoprotein-mediated xenobiotic secretion in renal proximal tubule. Am J Physiol 275: F785-95


  1. Ling-Hong Li, Robert N. Wine, David S. Miller, Jeffrey M. Reece, Marjo Smith, and Robert E. Chapin. Protection against methoxyacetic-acid-induced spermatocyte apoptosis with calcium channel blockers in cultured rat seminiferous tubules: possible mechanisms. Toxicol Appl Pharmacol 144: 105-119
  2. David S. Miller and John B. Pritchard. Dual pathways for organic anion secretion in renal proximal tubule. J Exp Zool 279: 462-670
  3. Carla M. Pedrosa Ribeiro, Jeffrey M. Reece, and James W. Putney Jr. Role of the cytoskeleton in calcium signaling in NIH 3T3 cells. An intact cytoskeleton is required for agonist-induced [Ca2+] signaling, but not for capacitative calcium entry. J Biol Chem 272: 26555-26561


  1. Rosalinde Masereeuw, W. C. Saleming, David S. Miller, and Frans G. M. Russel. Interaction of fluorescein with the dicarboxylate carrier in rat kidney cortex mitochondria. J Pharmacol Exp Therap 279: 1559-1565
  2. Rosalinde Masereeuw, Frans G. M. Russel, and David S. Miller. Multiple pathways of organic anion secretion in renal proximal tubule revealed by confocal fluorescence microscopy. Am J Physiol 271: F1173-F1182
  3. David S. Miller, S. Letcher, and David M. Barnes v Fluorescent imaging study of organic anion transport from renal proximal tubule cell to lumen. Am J Physiol 271: F508-F520
  4. John B. Pritchard and David S. Miller. Intracellular compartmentation of organic anions and cations during renal secretion. Cell Physiol Biochem 6: 50-59
  5. John B. Pritchard and David S. Miller. Renal secretion of organic cations: a multistep process. Kidney Int 49(6): 1649-54


  1. David S. Miller. Daunomycin secretion by killifish renal proximal tubules. Am J Physiol 269: R370-R379

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