Thomas Jefferson University

Cellular and Molecular Determinants of Birth Defects
Gerald B. Grunwald, Ph.D.
Department of Pathology, Anatomy and Cell Biology
Predoctoral, Postdoctoral Training
T32 ES07282

The training is provided by a core of basic science and clinical faculty who participate in the graduate program in Developmental Biology and Teratology, an interdepartmental program. The training approach is interdisciplinary and emphasizes the genetic and molecular bases of cellular function in developing systems, with the research interests falling within four overlapping categories:

• Cellular signals that mediate specific developmental transitions
• Signal transduction events that play a role in pathogenesis of birth defects
• Structure and function of the embryonic genome during development
• Mechanisms of developmental and reproductive toxicology

The core faculty collaborate with scientists at major pharmaceutical companies and teratology contract laboratories in the Philadelphia - New Jersey region, and with the Daniel Baugh Institute for functional genomics and computational biology.

E-mail contact: gerald.grunwald@jefferson.edu