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Meeting Agenda

Gene x Environment Interactions and Developmental Psychopathology: Research Challenges and Opportunities

June 27, 2006 –June 28, 2007
Washington, DC

June 27, 2006

Time Event Speaker(s)
9:00-9:15 Call to Order, Introductions, Purpose of Workshop Eve K. Mościcki, Sc.D., M.P.H.
National Institute of Mental Health
Welcoming Remarks Richard Nakamura, Ph.D.
Deputy Director, National Institute of Mental Health
Welcoming Remarks Wilson Comptom, M.D., M.P.E.
National Institute on Drug Abuse

Overview

Time
9:15-10:45
Moderator
Thomas Lehner, Ph.D.
National Institute of Mental Health
Time Event Speaker(s) Discussant(s)
9:15 Key Issues in Psychopathology Research in Developing Humans: Implications for GxE Maria Kovacs, Ph.D.
University of Pittsburgh
9:30 Gene-Environment Interaction: An Historical and Theoretical Introduction Kenneth S. Kendler, M.D.
Virginia Commonwealth University School of Medicine
  • Michael J. Shanahan, Ph.D.
    University of North Carolina
  • Jenae Neiderhiser, Ph.D.
    George Washington University
10:15 General Discussion

Where Are We Now in GxE Research Issues in Developmental Psychopathology?

Time
11:00-12:30
Moderator
Shelli Avenevoli, Ph.D.
National Institute of Mental Health
Time Event Speaker(s)
11:00 Genes, Epigenetics and Experience: Recent Findings in Rodents James Winslow, Ph.D.
National Institute of Mental Health
11:15 Current Studies of Gene x Environment: Interactions in Rhesus Monkeys and Other Nonhuman Primates Steve Suomi, Ph.D.
National Institute of Child Health and Human Development
11:30 Studies in Human Children and Adolescents Terrie E. Moffitt, Ph.D.
King's College London and the University of Wisconsin-Madison
11:45 Gene x Environment Interaction Studies in Adults: Examples from Non-psychiatric Disorders Kathleen Merikangas, Ph.D.
National Institute of Mental Health
12:00 Summary of Major Themes David Reiss, M.D.
George Washington University
12:10 General Discussion

Working Lunch

Time
12:30-1:30

Exploring Problems in GxE: Conceptual and Statistical Challenges

Time
1:30-2:45
Moderator
Kenneth S. Kendler, M.D.
Virginia Commonwealth University School of Medicine
Time Event Speaker Discussant(s)
1:30-2:00 Introduction Lindon Eaves, M.A. (Oxon), Ph.D., D.Sc.
Virginia Commonwealth University School of Medicine
2:00 Introduction
  • Joe Terwilliger, Ph.D.
    Columbia University
  • Jurg Ott, Ph.D.
    Yale University
  • Josephine Hoh, Ph.D.
    Yale University
2:30 General Discussion

Break

Time
2:45-3:00

Major Challenges in Application of GxE Paradigms to Developmental Psychopathology

Time
3:00-5:00
Moderator
Maria Kovacs, Ph.D.
University of Pittsburgh
Time Event Speaker(s)
3:00 Assessing the Environment in Developmental Psychopathology Research: A Behavioral Geneticist's Perspective Matt McGue, Ph.D.
University of Minnesota
3:15 Phenotype Refinement in Developmental Psychopathology: a Gender, Developmental, Informant, and Culturally Sensitive Approach James Hudziak, M.D.
University of Vermont
3:30 Cross-national Psychiatric Epidemiological Collaborations Involving Genetics Research: Issues, Challenges and Opportunities Sergio Aguilar-Gaxiola, M.D., Ph.D.
University of California-Davis
3:45 Translational Approaches to Understanding Mechanisms of Genetic x Environmental Interactions Joan Kaufmann, Ph.D.
Yale University
4:00 Genotype x Environment Interaction Mechanisms “Outside the Skin”: Implications for Preventive Interventions David Reiss, M.D.
George Washington University
4:15 Summary of Major Themes Terrie E. Moffitt, Ph.D.
King's College London and the University of Wisconsin-Madison
4:25 General Discussion

June 28, 2006

How Useful is the Gene x Environment Paradigm for Research in Pediatric Populations?

Time
9:00-11:45
Moderator
Kathleen Merikangas, Ph.D.
National Institute of Mental Health
Time Event Speaker(s)
9:00 An epidemiologic perspective:
  • Jane Costello, Ph.D.
    Duke University
  • Deborah Capaldi, Ph.D.
    Oregon Social Learning Center
9:30 A preventive and treatment intervention perspective:
  • Gabrielle A. Carlson, M.D.
    SUNY-Stony Brook
  • Dante Cicchetti, Ph.D.
    University of Minnesota
  • Leslie Leve, Ph.D.
    Oregon Social Learning Center
  • José Szapocznik, Ph.D.
    University of Miami

General Discussion

Time
10:45-11:45

Summary, Issues for Consideration for Organizing a Research Strategy, and Next Steps

Time
11:45-12:30
Moderator
Eve K. Mościcki, Sc.D., M.P.H.
National Institute of Mental Health

Adjourn