Aimee D’Aloisio
Predoctoral Fellow Tel (919) 541-3253 Fax (919) 541-2511 daloisio@niehs.nih.gov Curriculum Vitae (http://www.niehs.nih.gov/research/atniehs/labs/epi/women/staff/daloisio/daloisio_cv.pdf) P.O. Box 12233 Mail Drop A3-05 Research Triangle Park, North Carolina 27709 Delivery Instructions Aimee D'Aloisio's research at NIEHS has focused on the etiology of uterine fibroids. Under the mentorship of Donna Baird, Ph.D, D’Aloisio used data from the NIEHS Uterine Fibroid Study to explore the association of alcohol intake with uterine fibroids. Bayesian methods developed by David Dunson, Ph.D., further support her analysis that alcohol intake is involved in the onset rather than the progression of uterine fibroids (D'Aloisio et al., 2007). Increase in incidence of uterine fibroids was evident for those reporting intake of 0.5 to 2 drinks per week among Caucasian women; however, among African-American women, the increase occurred principally for those reporting at least seven drinks per week. D'Aloisio’s dissertation research involves the relationship of insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 (IGFBP-3) polymorphisms and estimated haplotypes with the prevalence and growth of uterine fibroids using data and stored blood specimens from the NIEHS Uterine Fibroid Study. Secondarily, she is examining whether the IGF-I and IGFBP-3 polymorphisms and estimated haplotypes predict IGF-I and IGFBP-3 plasma levels. Her research will advance the understanding of the biological mechanisms that cause uterine fibroids and may help explain racial disparities in their prevalence and morbidity. Studies
Selected Publications
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