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| Topic: |
Kidney and Urologic Diseases (KU) |
| Title: |
Glomerular Disease. |
| Author: |
Haymart, M.R.; Atta, M.G. |
| Source: |
IN: Nilsson, K.R.; Piccini, J.P., eds. Osler Medical Handbook. Philadelphia, PA: Saunders. 2006. pp. 719-730. |
| Availability: |
Available from Saunders. Curtis Centre, Independence Square West, Philadelphia, PA 19106. Website: www.us.elsevierhealth.com. Price: 49.95. |
| Abstract: |
This chapter on glomerular disease is from a handbook that provides the essentials of diagnosis and treatment, as well as the latest in evidence-based medicine, for residents working bedside, in-patient care. The chapter begins with a presentation of essential Fast Facts and concludes with Pearls and Pitfalls useful to the practicing internist. The body of the chapter is divided into sections: Epidemiology, Clinical Presentation, Diagnosis, and Management. Specific topics covered in this chapter include the role of glomerulonephritis as a cause of end-stage renal disease (ESRD); nephritic syndrome, which is characterized by red blood cells and casts on urine microscopy, hypertension, renal insufficiency, mild proteinuria, and edema; nephrotic syndrome, which is characterized by more than 3 grams of proteinuria per day, low serum albumin, edema, and dyslipidemia; membranoproliferative glomerulonephritis; diagnostic strategies that include seeking secondary causes of glomerular disease, which include HIV and hepatitis; the treatment of primary glomerular disease, which can include steroids and cytotoxic agents; the use of ACE inhibitors and ARBs to reduce proteinuria and prevent further decline in glomerular filtration rate (GFR) in patients with glomerular disease; and the use of antihypertensive agents, cholesterol-lowering agents, and sodium restriction and diuretics in these patients. The chapter concludes with a list of references, each labeled with a 'strength of evidence' grade to help readers determine the type of research available in that reference source. 2 figures. 1 table. 19 references. |
| Format: |
Book Chapter |
| Language: |
English. |
| Major Keywords: |
Kidney Diseases. Glomerulonephritis. Kidney Glomerulus. Nephrotic Syndrome. Etiology. Diagnosis. Symptoms. Epidemiology. Patient Care Management. Diagnostic Tests. |
| Minor Keywords: |
Emergencies. Patient Selection. Risk Factors. Morbidity. Mortality. Hospital Care. Complications. Drug Therapy. Urine Testing. Proteinuria. Drug Effects. Glomerular Filtration Rate. |
| Publication Number: |
KUBK11441. |
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