Department of Health and Human Services - www.hhs.gov
Department of Health and Human Services - www.hhs.gov
healthfinder.gov - A Service of the National Health Information Center, U.S. Department of Health and Human Services

 

healthfinder.gov Home   |   About Us   |   News   |   Health Library   |   Consumer Guides   |   Organizations   |   En Español   |   Kids   |   Contact Us

Home > News

Hydrating Kidney Patients With Sodium Bicarb Has Little Effect

Study shows it was no better than sodium chloride in preventing problems during screening.

  • E-mail this article
  • Subscribe to news
  • Printer friendly version
  • (SOURCE: Columbia University, news release, Sept. 3, 2008)

    WEDNESDAY, Sept. 3 (HealthDay News) -- Hydrating kidney disease patients with sodium bicarbonate during coronary angiography is no more effective in reducing the risk of serious kidney disease than hydration with sodium chloride, researchers say.

    Nephropathy is a serious kidney disorder and a known complication of exposure to the iodine in the contrast agent used during angiography. The risk of nephropathy related to contrast agents ranges from 2 percent in low-risk people to 50 percent in those who are at high-risk.

    Previous animal studies and one randomized clinical trial have suggested that hydration with sodium bicarbonate may be effective in preventing contrast-induced nephropathy.

    A new study in the Sept. 3 Journal of the American Medical Association looked at 353 people with moderate to severe kidney disease who were undergoing coronary angiography. The researchers randomly assigned the patients to receive either sodium chloride or sodium bicarbonate before, during, and after their angiography.

    Overall, 13.9 percent of the patients developed contrast-induced nephropathy.

    There was no difference between the sodium chloride and the sodium bicarbonate groups in terms of developing nephropathy. Nor were there differences between the groups in the rates of death, dialysis, heart attack, and cerebrovascular events.

    These findings suggest that hydration with sodium bicarbonate is not superior to hydration with sodium chloride in kidney disease patients who are undergoing coronary angiography, say the researchers.

    "Any true difference between the hydration strategies is likely to be small and not clinically significant," the study's authors wrote.

    More information

    The National Heart, Lung, and Blood Institute has more about coronary angiography.

    Copyright © 2008 ScoutNews, LLC. All rights reserved.  External Links Disclaimer Logo

    HealthDayNews articles are derived from various sources and do not reflect federal policy. healthfinder.gov does not endorse opinions, products, or services that may appear in news stories. For more information on health topics in the news, visit the healthfinder.gov health library.

    healthfinder.gov logo USA dot Gov: The U.S. Government’s Official Web Portal
    footer shadow