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thiotepa
A synthetic alkylating agent. Related to nitrogen mustard, thiotepa alkylates and crosslinks DNA, resulting in the inhibition of DNA replication. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | Thiophosphamide
Thiophosphoramide
triethylene thiophosphoramide | | | | US brand names: | | Girostan
STEPA
TESPA
Thiofozil
Thioplex
Tifosyl | | | | Foreign brand names: | | Ledertepa
Onco Tiotepa
Oncotiotepa
Tespamin
Tespamine
Thiotef
Tio-TEF | | | | Abbreviation: | | TSPA | | | | Code name: | | WR 45312 | | | | Chemical structure names: | | - 1,1',1"-phosphinothioylidynetrisaziridine
- 1,1',1''-Phosphinothioyldynetrisaziridine
- N,N',N''-triethylenethiophosphoramide
- tris(1-aziridinyl)phosphine sulfide
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