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monoclonal antibody HuM291 A humanized monoclonal antibody deficient in Fc receptor binding directed against CD3 on the surfaces of T cells. Monoclonal antibody HuM291 binds to the CD3 portion of the CD3:TCR (T-cell receptor) complex expressed on the surface of T cells, resulting in apoptosis of antigen-activated T cells., Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20081005094032im_/http://www.nci.nih.gov/images/spacer.gif) | Anti CD3 Anti-CD3 Antibody HuM291 HUM291 [Anti-CD3 Antibody] | | ![](https://webarchive.library.unt.edu/eot2008/20081005094032im_/http://www.nci.nih.gov/images/spacer.gif) | Abbreviation: | ![](https://webarchive.library.unt.edu/eot2008/20081005094032im_/http://www.nci.nih.gov/images/spacer.gif) | MOAB HuM291 | | ![](https://webarchive.library.unt.edu/eot2008/20081005094032im_/http://www.nci.nih.gov/images/spacer.gif) |
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