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telomerase: 540-548 peptide vaccine A recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT). Telomerase expression has been directly linked to tumor development; its catalytic subunit is expressed in the majority of human cancer cells, but infrequently in normal cells. Vaccination with telomerase:540-548 peptide may stimulate cytotoxic T cells to recognize and kill telomerase-expressing cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20081005055403im_/http://www.nci.nih.gov/images/spacer.gif) | Telomerase:540-548 Peptide | | ![](https://webarchive.library.unt.edu/eot2008/20081005055403im_/http://www.nci.nih.gov/images/spacer.gif) | Abbreviation: | ![](https://webarchive.library.unt.edu/eot2008/20081005055403im_/http://www.nci.nih.gov/images/spacer.gif) | TEL540-548 | | ![](https://webarchive.library.unt.edu/eot2008/20081005055403im_/http://www.nci.nih.gov/images/spacer.gif) |
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