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transgenic lymphocyte immunization vaccine
A vaccine consisting of a preparation of allogeneic lymphocytes that encode a gene for telomerase. In transgenic lymphocyte immunization, the transgenic cells are infused into the patient, where they serve as antigen- presenting cells (APCs) with the dual function of antigen synthesis and presentation. Vaccination produces an immune response targeting cancer cells expressing telomerase. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | TLI vaccine | | |
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