McKesson 

The indicator monitors temperature exposure, not product quality

Vaccine Temperature Management
A ColdMark™ Freeze Indicator has been packaged with this shipment by McKesson to assure that the enclosed vaccines have been shipped under manufacturer-recommended conditions.

Receiver Instructions
Immediately upon shipment receipt:
• Remove the ColdMark Freeze Indicator from the shipment container
• Store vaccines as instructed below
• Follow instructions on reverse side to utilize the ColdMark Freeze Indicator properly

Vaccine Storage Requirements
• Take the product out of the shipment container immediately upon shipment receipt
• If damage is evident, contact your Project Point of Contact (PPOC) within 2 hours of shipment receipt
• Remove the product from the zippered plastic bag
• Refrigerate immediately
• Store at 35° to 46°F (2° to 8°C)
• Do not freeze or expose to freezing temperatures

How to Read
Immediately upon shipment receipt, remove the ColdMark Freeze Indicator and check the ColdMark bulb.
• If the bulb is clear and colorless, begin using vaccine as needed.
• If the bulb appears violet in color, store the product as instructed and contact your PPOC for further instructions prior to using.

ColdMark Freeze Indicator decision table:
Vaccine type: MMR, ActHIB, LAIV
Clear and colorless:  Begin using vaccine
Violet: Begin using vaccine

Vaccine type: All other vaccine 
Clear and colorless:  Begin using vaccine 
Violet: Contact PPOC

This document can be found on the CDC website at:
http://www.cdc.gov/vaccines/programs/vmbip/downloads/ipcrd-cldmrk-reprnt.rtf