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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Andrea Bucceri
Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents.
BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.
Featured articles
BMC Pharmacology 2008, 8 :11
A metabolite of anxiolytic ocinaplon, DOV 315,090, has a similar pharmacological profile to ocinaplon itself, implying that DOV 315,090 could contribute to the action of ocinaplon but may not be responsible for its non-sedating effects.
BMC Pharmacology 2008, 8 :10
Benfotiamine, a non-prescription thiamine precursor indicated for a variety of disorders, has poor lipid solubility and is predicted to have little effect in central nervous system thiamine deficiencies compared with other precursors, despite widespread claims regarding its efficacy.
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Research article
Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.) Pal A Olsvik, Kai K Lie, Eva Mykkeltvedt, Ole B Samuelsen, Kjell Petersen, Anne-Kristin Stavrum, Bjorn T Lunestad BMC Pharmacology 2008, 8 :16 (11 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Methoxylation enhances stilbene bioactivity in Caenorhabditis elegans Mark A Wilson, Agnes M Rimando, Catherine A Wolkow BMC Pharmacology 2008, 8 :15 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats Rajeshkumar U Koladiya, Amteshwar S Jaggi, Nirmal Singh, Bhupesh K Sharma BMC Pharmacology 2008, 8 :14 (9 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A classification model to predict synergism/antagonism of cytotoxic mixtures using protein-drug docking scores John C Boik, Robert A Newman BMC Pharmacology 2008, 8 :13 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Structure-activity models of oral clearance, cytotoxicity, and LD50: a screen for promising anticancer compounds John C Boik, Robert A Newman BMC Pharmacology 2008, 8 :12 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
Pharmacological Properties of DOV 315,090, an ocinaplon metabolite Dmytro Berezhnoy, Maria C Gravielle, Scott Downing, Emmanuel Kostakis, Anthony S Basile, Phil Skolnick, Terrell T Gibbs, David H Farb BMC Pharmacology 2008, 8 :11 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives Marie-Laure Volvert, Sandrine Seyen, Marie Piette, Brigitte Evrard, Marjorie Gangolf, Jean-Christophe Plumier, Lucien Bettendorff BMC Pharmacology 2008, 8 :10 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [1 comment ]
Research article
Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells Jillian G Baker BMC Pharmacology 2008, 8 :9 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Comparison of four different colorimetric and fluorometric cytotoxicity assays in a zebrafish liver cell line Stephanie K Bopp, Teresa Lettieri BMC Pharmacology 2008, 8 :8 (30 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
RU486 did not exacerbate cytokine release in mice challenged with LPS nor in db/db mice Baichun Yang, Ryan P Trump, Ying Shen, Judi A McNulty, Lisa G Clifton, Stephen A Stimpson, Peiyuan Lin, Greg L Pahel BMC Pharmacology 2008, 8 :7 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver: comparison of rat and mouse Paul C Boutros, Rui Yan, Ivy D Moffat, Raimo Pohjanvirta, Allan B Okey BMC Genomics 2008, 9 :419 (16 [Abstract ] [Provisional PDF ]
Review
Off-label psychopharmacologic prescribing for children: history supports close clinical monitoring Julie M Zito, Albert T Derivan, Christopher Kratochvil, Daniel J Safer, Joerg M Fegert, Lawrence L Greenhill Child and Adolescent Psychiatry and Mental Health 2008, 2 :24 (15 [Abstract ] [Provisional PDF ]
Case report
Fatal hemolytic anemia associated with Metformin: a case report Clifford D Packer, Thomas R Hornick, Sarah A Augustine Journal of Medical Case Reports 2008, 2 :300 (10 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells Huaying Liu, Liming Zhang, Zhaoxia Niu, Ming Zhou, Cong Peng, Xiayu Li, Tan Deng, Lei Shi, Yixin Tan, Guiyuan Li BMC Cancer 2008, 8 :253 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Case Report
Doxycycline-induced ulceration mimicking esophageal cancer: a case report Veysel Tahan, Hakan Sayrak, Nevzat Bayar, Burak Erer, Gulgun Tahan, Faysal Dane Cases Journal 2008, 1 :144 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Up-regulation of endothelin type B receptors in the human internal mammary artery during culture is dependent on protein kinase C and mitogen-activated kinase signaling pathways David Nilsson, Lotta Gustafsson, Angelica Wackenfors, Bodil Gesslein, Lars Edvinsson, Per Paulsson, Richard Ingemansson, Malin Malmsjo BMC Cardiovascular Disorders 2008, 8 :21 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Plasmodium falciparum gametocyte sex ratios in children with acute, symptomatic, uncomplicated infections treated with amodiaquine Akintunde Sowunmi, Sulayman T Balogun, Grace O Gbotosho, Christian T Happi Malaria Journal 2008, 7 :169 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Anti-inflammatory effects of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) in animal models Kyoung Soo Kim, Hae In Rhee, Eun Kyung Park, Kiwon Jung, Hyo Jin Jeon, Ji-Hong Kim, Hunseung Yoo, Chang-Kyun Han, Young-Back Cho, Chun Jeih Rhu, Hyung In Yang, Myung Chul Yoo Chinese Medicine 2008, 3 :10 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Effect of roflumilast on inflammatory cells in the lungs of cigarette smoke-exposed mice Piero A Martorana, Benedetta Lunghi, Monica Lucattelli, Giovanna De Cunto, Rolf Beume, Giuseppe Lungarella BMC Pulmonary Medicine 2008, 8 :17 (28 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The co-administration of quetiapine or placebo to cognitive-behavior therapy in treatment refractory depression; a preliminary trial Yves Chaput, Annick Magnan, Alain Gendron BMC Psychiatry 2008, 8 :73 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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