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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Andrea Bucceri
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of transcription, mRNA processing, translation, replication, recombination, mutation, and repair.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
BMC Molecular Biology 2008, 9 :68
Optical mapping, a single molecule approach for genome-wide DNA mapping, can now be used for the detection of DNA methylation profiles and will facilitate rapid advances in understanding the epigenetic regulation of eukaryotic genomes.
BMC Molecular Biology 2008, 9 :55
The histone acetyltransferase MOF is essential for dosage compensation in Drosophila and also downregulates the copia retrotransposon, implying that MOF originally functioned to silence retrotransposons and was later co-opted into regulating dosage compensation.
BMC Molecular Biology 2008, 9 :41
Interactions between the transcriptional repressors and activators of the mammalian circadian clock occur with different affinities, with CRY repressor proteins more potent as inhibitors than PER repressor proteins in mammalian two-hybrid and co-immunoprecipitation assays.
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Research article
Sense and Antisense OsDof12 Transcripts in Rice Dejun Li, Chunhua Yang, Xiaobing Li, Guobiao Ji, Lihuang Zhu BMC Molecular Biology 2008, 9 :80 (17 [Abstract ] [Provisional PDF ]
Research article
Evaluation of suitable reference genes for gene expression studies in bovine muscular tissue Raquel Perez, Isabel Tupac-Yupanqui, Susana Dunner BMC Molecular Biology 2008, 9 :79 (11 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Selection of internal reference genes for SYBR green qRT-PCR studies of rhesus monkey (Macaca mulatta) tissues Kung Ahn, Jae-Won Huh, Sang-Je Park, Dae-Soo Kim, Hong-Seok Ha, Yun-Ji Kim, Ja-Rang Lee, Kyu-Tae Chang, Heui-Soo Kim BMC Molecular Biology 2008, 9 :78 (10 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Phi29 polymerase based random amplification of viral RNA as an alternative to random RT-PCR Nicolas Berthet, Anita K Reinhardt, India Leclercq, Sven van Ooyen, Christophe Bat BMC Molecular Biology 2008, 9 :77 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Identification of suitable endogenous control genes for microRNA gene expression analysis in human breast cancer Pamela A Davoren, Roisin E McNeill, Aoife J Lowery, Michael J Kerin, Nicola Miller BMC Molecular Biology 2008, 9 :76 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Normalisation genes for expression analyses
in the brown alga model Ectocarpus siliculosus.
Aude Le Bail, Simon M Dittami, Pierre-Olivier de Franco, Sylvie Rousvoal, Mark J Cock, Thierry Tonon, Benedicte Charrier BMC Molecular Biology 2008, 9 :75 (18 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells Stephanie Cabarcas, Joby Jacob, Ingrid Veras, Laura Schramm BMC Molecular Biology 2008, 9 :74 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Mutational analysis of highly conserved aspartate residues essential to the catalytic core of the piggyBac transposase James H Keith, Cheryl A Schaeper, Tresa S Fraser, Malcolm J Fraser Jr BMC Molecular Biology 2008, 9 :73 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Analysis of the piggyBac transposase reveals a functional nuclear targeting signal in the 94 c-terminal residues James H Keith, Tresa S Fraser, Malcolm J Fraser Jr BMC Molecular Biology 2008, 9 :72 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
In vivo analysis of Caenorhabditis elegans noncoding RNA promoter motifsTiantian Li, Housheng He, Yunfei Wang, Haixia Zheng, Geir Skogerb BMC Molecular Biology 2008, 9 :71 (5 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia
Claude Lamarre, Serguei Sokol, Jean-Paul Debeaupuis, Christine Henry, Celine Lacroix, Philippe Glaser, Jean-Yves Coppee, Jean-Marie Francois, Jean-Paul Latge BMC Genomics 2008, 9 :417 (16 [Abstract ] [Provisional PDF ]
Research article
Prediction of Sinorhizobium meliloti sRNA genes and experimental detection in strain 2011 Claudio Valverde, Jonathan Livny, Jan-Philip Schluter, Jan Reinkensmeier, Anke Becker, Gustavo Parisi BMC Genomics 2008, 9 :416 (16 [Abstract ] [Provisional PDF ]
Research article
Functional analyses reveal an important role for tyrosine residues in the staphylococcal multidrug efflux protein QacA Jingqin Wu, Karl A Hassan, Ronald A Skurray, Melissa H Brown BMC Microbiology 2008, 8 :147 (16 [Abstract ] [Provisional PDF ]
Research
Subcellular forms and biochemical events triggered in human cells by HCV polyprotein expression from a viral vector Andree M Vandermeeren, Carmen Elena Gomez, Cristina Patino, Elena Domingo-Gil, Susana Guerra, Jose Manuel Gonzalez, Mariano Esteban Virology Journal 2008, 5 :102 (15 [Abstract ] [Provisional PDF ]
Methodology article
Molecular analysis of chondrocytes cultured in agarose in response to dynamic compression Carole Bougault, Anne Paumier, Elisabeth Aubert-Foucher, Frederic Mallein-Gerin BMC Biotechnology 2008, 8 :71 (15 [Abstract ] [Provisional PDF ]
Methodology
PCR-based detection of Plasmodium in Anopheles mosquitoes: a comparison of a new high-throughput assay with existing methods Chris Bass, Dimitra Nikou, Andrew M Blagborough, John Vontas, Robert E Sinden, Martin S Williamson, Linda M Field Malaria Journal 2008, 7 :177 (15 [Abstract ] [Provisional PDF ]
Review
Unravelling the adaptation responses to osmotic and temperature stress in Chromohalobacter salexigens, a bacterium with broad salinity tolerance Carmen Vargas, Montserrat Argandona, Mercedes Reina-Bueno, Javier Rodriguez-Moya, Cristina Fernandez-Aunion, Joaquin J Nieto Saline Systems 2008, 4 :14 (15 [Abstract ] [Provisional PDF ]
Research
Identification of genes down-regulated during lung cancer progression: a cDNA array study Mara Campioni, Vincenzo Ambrogi, Eugenio Pompeo, Gennaro Citro, Mauro Castelli, Enrico P Spugnini, Antonio Gatti, Pierluigi Cardelli, Laura Lorenzon, Alfonso Baldi, Tommaso C Mineo Journal of Experimental & Clinical Cancer Research 2008, 27 :38 (15 [Abstract ] [Provisional PDF ]
Research
Descending serotonergic controls regulate inflammation-induced mechanical sensitivity and methyl-CpG-binding protein 2 phosphorylation in the rat superficial dorsal horn Sandrine M Geranton, Vincenza Fratto, Keri K Tochiki, Steve P Hunt Molecular Pain 2008, 4 :35 (15 [Abstract ] [Provisional PDF ]
Research article
YB-1 promotes microtubule assembly in vitro through interaction with tubulin and microtubules Konstantin G Chernov, Alain Mechulam, Nadezhda V Popova, David Pastre, Elena S Nadezhdina, Olga V Skabkina, Nina A Shanina, Viktor D Vasiliev, Anne Tarrade, Judith Melki, Vandana Joshi, Sonia Baconnais, Flavio Toma, Lev P Ovchinnikov, Patrick A Curmi BMC Biochemistry 2008, 9 :23 (15 [Abstract ] [Provisional PDF ]
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