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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Andrea Bucceri
Welcome to BMC Chemical Biology published by BioMed Central
BMC Chemical Biology is an open access journal publishing original peer-reviewed research articles in the application of chemistry to the investigation of biology and drug design.
BMC Chemical Biology (ISSN 1472-6769) is indexed/tracked/covered by PubMed, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.
BMC Chemical Biology 2008, 8 :2
Inducing apoptosis using compounds screened from a chemical library demonstrates that calcium signaling is generally not an early event and suggests that the calmodulin kinase II pathway is often important in sustaining apoptosis.
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Research article
Chemogenetic fingerprinting by analysis of cellular growth dynamics Jonas Warringer, Dragi Anevski, Beidong Liu, Anders Blomberg BMC Chemical Biology 2008, 8 :3 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II Maria H BMC Chemical Biology 2008, 8 :2 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae Lorena Norambuena, Jan Zouhar, Glenn R Hicks, Natasha V Raikhel BMC Chemical Biology 2008, 8 :1 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Enhancement of intracellular Yuichiro Tanaka, Leslie A Lesoon Wood, Robert V Cooney BMC Chemical Biology 2007, 7 :2 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The effect of amino acid deletions and substitutions in the longest loop of GFP Gabriela Flores-Ram BMC Chemical Biology 2007, 7 :1 (26 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Studies on the synthesis, characterization, binding with DNA and activities of two cis -planaramineplatinum(II) complexes of the form: cis -PtL(NH3 )Cl2 where L = 3-hydroxypyridine and 2,3-diaminopyridine Ahmed Abdullah, Fazlul Huq, Ashraf Chowdhury, Hasan Tayyem, Philip Beale, Keith Fisher BMC Chemical Biology 2006, 6 :3 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol Zoltan Maliga, Timothy J Mitchison BMC Chemical Biology 2006, 6 :2 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator Justin J Heynekamp, Lucy A Hunsaker, Thomas A Vander Jagt, Lorraine M Deck, David L Vander Jagt BMC Chemical Biology 2006, 6 :1 (8 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Covalent attachment of the plant natural product naringenin to small glass and ceramic beads Yuhua Lu, Niloufer G Irani, Erich Grotewold BMC Chemical Biology 2005, 5 :3 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Electronic properties of amino acid side chains: quantum mechanics calculation of substituent effects Donard S Dwyer BMC Chemical Biology 2005, 5 :2 (3 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Virtual screening of GPCRs: an in silico chemogenomics approach Laurent Jacob, Brice Hoffmann, Veronique Stoven, Jean-Philippe Vert BMC Bioinformatics 2008, 9 :363 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development Kevin S Jones, Alexander P Alimov, Horacio L Rilo, Ronald J Jandacek, Laura A Woollett, W Todd Penberthy Nutrition & Metabolism 2008, 5 :23 (27 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
Effect of benthic boundary layer transport on the productivity of Mono Lake, California Louise C Bruce, Robert Jellison, J Saline Systems 2008, 4 :11 (19 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Myosin-Vb functions as a dynamic tether for peripheral endocytic compartments during transferrin trafficking D William Provance Jr, Erin J Addison, Patrick R Wood, David Z Chen, Colleen M Silan, John A Mercer BMC Cell Biology 2008, 9 :44 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
High-throughput gene expression profiling of memory differentiation in primary human T cells W Nicholas Haining, Jill Angelosanto, Kathleen Brosnahan, Kenneth Ross, Cynthia Hahn, Kate Russell, Linda Drury, Stephanie Norton, Lee Nadler, Kimberly Stegmaier BMC Immunology 2008, 9 :44 (1 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: Mechanistic implications Laure Gabison, Thierry Prang BMC Structural Biology 2008, 8 :32 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Silymarin protects liver against toxic effects of anti-tuberculosis drugs in experimental animals Sude Eminzade, Fikriye Uraz, Fikret V Izzettin Nutrition & Metabolism 2008, 5 :18 (5 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Molecular evolution of B6 enzymes: Binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme Rosa A Vacca, Sergio Giannattasio, Guido Capitani, Ersilia Marra, Philipp Christen BMC Biochemistry 2008, 9 :17 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
LuxS-independent formation of AI-2 from ribulose-5-phosphate Timothy J Tavender, Nigel M Halliday, Kim R Hardie, Klaus Winzer BMC Microbiology 2008, 8 :98 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells Jillian G Baker BMC Pharmacology 2008, 8 :9 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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