NIH Clinical Research Studies Listed By Institute of the Principal Investigator

National Institute of Allergy and Infectious Diseases (NIAID)

139 Protocols (106 Active Accrual of new subjects, 33 Follow-up of previously enrolled subjects)


Active Accrual, Protocols Recruiting New Patients 
* 87-I-0163:
Apheresis Procedures to Obtain Plasma or Leukocytes for In Vitro Studies

* 85-I-0127:
Treatment of Patients with Cysticercosis with Praziquantel, Albendazole and Other Novel Treatment Modalities

* 82-I-0183:
Study of the Immune Regulation of Idiopathic Inflammatory Bowel Diseases: Crohn's Disease, Ulcerative Colitis, and Other Inflammatory Conditions of the Gut

* 81-I-0164:
Apheresis Procedures to Obtain Plasma or Lymphocytes for In Vitro Studies

* 78-I-0023:
Diagnosis and Management of Inflammatory and Infectious Diseases

* 77-I-0094:
Study of Patients with Parasitic Infections of the Gastrointestinal Tract

Active Follow-up, Protocols NOT Recruiting New Patients 

* 07-I-0172:
A Phase I Open-Label Study of the Safety and Immunogenicity of a Recombinant DNA Plasmid Vaccine, VRC-AVIDNA036-00-VP, Encoding for the Influenza Virus H5 Hemagglutinin Protein Administered Intradermally in Healthy Adults

* 07-I-0155:
A Ph I/IIa Rand Placebo Ctrl, S-Blind Multictr Dose-Esc Study of SC Intermittent Interleukin-7 CYT107 in Chronically HIV-Infected Pts with CD4 T Lymphocyte Counts 101-400 Cells-/mm(3) and Plasma HIV RNA Less Than 50 copies/mL After at Least 12 M of HAART

* 07-I-0083:
Phase I Study of the Safety and Immunogenicity of AMA1-C1/Alhydrogel + CPG 7909, an Asexual Blood Stage Vaccine for Plasmodium Falciparum Malaria

* 06-I-0180:
Evaluation of Alternative Oseltamivir (Tamiflu[R]) Dosing Strategies for Use during Influenza Prophylaxis

* 06-I-0149:
VRC 011: A Phase I Clinical Trial of Intramuscular, Subcutaneous and Intradermal Administration of an HIV-1 Multiclade DNA Vaccine, VRC-HIVDNA016-00-VP, and an HIV-1 Multiclade Adenoviral Vector Vaccine,VRC-HIVADV014-00-VP, in Uninfected Adult Volunteer

* 06-I-0105:
A Phase I Double-Blind, Placebo-Controlled, Dose-Escalating Study to Evaluate the Safety and Tolerability of Intravenous Peramivir in Healthy Subjects

* 06-I-0056:
VRC101: A Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of a Prime-Boost HIV-1 Vaccination Schedule of a 6-Plasmid Multiclade HIV-1 DNA Vaccine, VRC-HIVDNA016-00-VP, Followed by a Recombinant Multiclade Adenoviral Vector HIV Vaccine

* 05-I-0133:
Phase 1 Study of the Safety of Immunization of Naive Individuals with AMA1-C1/Alhydrogel [R], an Asexual Blood-Stage Vaccine for Plasmodium Falciparum Malaria, and the Effect of Immunization on Antigen-specific Memory and Plasma B Cells and T Cells

* 05-I-0108:
A Multicenter, Open-Label, Study of Extracorporeal Photoimmune Therapy with UVADEX in the Treatment of Patients with Moderately Active Crohn's Disease Who Are Refractory or Intolerant to Immunosuppressants and/or Anti-TNF Agents

* 05-I-0065:
A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Effect of Leflunomide on HIV-1 Associated Immune Proliferation In Vivo

* 04-I-0289:
Secondary Transplantation Using Moderate Dose Busulfan as Conditioning for a Patient with Partial Reconstitution Post Initial Allogeneic Transplantation

* 04-I-0266:
Collection of Peripheral Blood and Bone Marrow From Healthy Donors for Use in In Vitro Research

* 04-I-0187:
A Randomized Controlled Trial to Evaluate the Safety and Efficacy of Twice-Weekly Peginterferon Alpha 2a and Ribavirin Induction Therapy for Chronic Hepatitis C in Patients who are Coinfected with HIV-1

* 04-I-0176:
Pilot Study of Omalizumab in Eosinophilic Gastroenteritis

* 04-I-0172:
A Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of a Recombinant Multiclade HIV-1 Adenoviral Vector Vaccine, VRC-HIVADV014-00-VP, in Uninfected Adult Volunteers

* 04-I-0158:
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Phase III Study to Evaluate Corticosteroid-Reduction and -Sparing Effects of Mepolizumab 750 mg Intravenous in Subjects with Hypereosinophilic Syndromes (HES), and to evaluate th

* 04-I-0126:
Exhaled Breath Condensate as a Measurement of Airway Inflammation in Children with Asthma

* 04-I-0018:
Phase II/III Study Evaluating the Effect of IL-2 on Preservation of the CD4 T-Lymphocytes After Interruption of Anti-Retroviral Treatment in HIV Infected Patients with CD4 T-Lymphocyte Count Greater Than 500 Cells/mm(3) Who Have Received Anti-Retroviral

* 03-I-0022:
A Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of a Multiclade HIV-1 DNA Plasmid Vaccine, VRC-HIVDNA009-00-VP in Uninfected Adult Volunteers

* 01-I-0171:
Substudies of ESPRIT: ESPRIT Influenza Vaccine Substudy (FLUVAC) and ESPRIT Tetanus-Pneumococcal Vaccine Substudy (TEPVAC)

* 01-I-0126:
A Phase III Multicenter Randomized Study of the Biological and Clinical Efficacy of Subcutaneous Recombinant, Human Interleukin-2 in HIV-Infected Patients with Low CD4+ Counts Under Active Antiretroviral Therapy (SILCAAT Amendment 4)

* 00-I-0163:
Persistence of Epstein-Barr Virus in Vivo

* 00-I-0143:
Chemokine System Polymorphisms and Risk of Atherosclerosis (CAD)

* 00-I-0110:
Analysis of HIV Genetic Variation in Patients Prior to Initiation of Highly Active Antiretroviral Therapy

* 00-I-0071:
Randomized, Open-Label, Phase III, International Study of Recombinant IL-2 (Proleukin) in Pts. w/HIV-1 Infection and CD4 Cell Counts Greater than or Equal to 300 Cells/mm3: Eval of Subcutaneous Proleukin in Randomized International Trial (ESPIRIT)

* 99-I-0149:
Analysis of the Occurrence of Perilesional Edema and Seizures in Patients With Inactive Cysticercosis

* 99-I-0106:
Trial of Varicella Vaccine for the Prevention of Herpes Zoster and Its Complications

* 99-I-0015:
Immunologic and Virologic Characterization of HIV-Infected Patients After Cessation of Highly Active Antiretroviral Therapy (HAART)

* 97-I-0189:
Studies of Lymphocyte Kinetics Using Bromodeoxyuridine

* 97-I-0166:
Polymorphism of the Herpes Simplex Virus Receptor

* 97-I-0082:
Use of Combination Antiviral Therapy to Delineate the Identity and Longevity of Persistent Reservoirs of HIV-1 Infection and Replication

* 95-I-0134:
Gene Therapy Approach for Chronic Granulomatous Disease

* 94-I-0203:
Cytokine Expression in Allergic Asthma

Previous 100 Protocols

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