Curriculum Vitae
Transmissible Spongiform Encephalopathies Advisory Committee
Glenn Christopher Telling , BA (Oxon.), MA (Oxon.), PhD
Professor of Microbiology, Immunology and Molecular Genetics
I. BIOGRAPHICAL INFORMATION
A. Education and Research Training
Undergraduate | Corpus Christi College, Oxford University, B.A. (Honors), Biochemistry, ---- |
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Graduate | Oxford University, M.A., Biochemistry, ---- Carnegie Mellon University - Ph.D. Biological Sciences, ---- Summer Research Fellow : Insertion mutagenesis of the vacuolar protease PRPB gene of Saccharomyces cerevisiae using the γδ transposon. Advisor - Elizabeth Jones, Ph.D., Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA Doctoral Thesis : ‘ Genetic analysis of the functions of the adenovirus E1 proteins in oncogenic transformation and lytic infection'. Advisor - James F. Williams, Ph.D., Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA |
Postgraduate | Jim Williams' Lab, Department of Biological Sciences, Carnegie Mellon University, Pittsburgh 1990-1991 Postdoctoral Fellow Stanley Prusiner's Lab , Department of Neurology, University of California, San Francisco 1991-1994 Postdoctoral Fellow |
B. Academic Appointments
Current Appointments at the University of Kentucky | |
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2007 - present | Professor of Microbiology, Immunology & Molecular Genetics(Primary Appointment) Professor of Neurology (Joint Appointment) Graduate Center for Gerontology ( Faculty Affiliate) Sanders-Brown Center on Aging ( Faculty Affiliate) |
Other Current Appointments | |
1998 - present | Department of Pathology, Colorado State University (Faculty Affiliate) |
2005 - present | Institute of Biological Sciences/Technology, Beijing Jiaotong University, China (Honorary Visiting Professor) |
Previous Appointments | |
1994-1996 | Assistant Research Molecular Biologist, Department of Neurology, University of California, San Francisco |
1996-1997 | Assistant Professor, Department of Neurology, University of California, San Francisco |
1997-1999 | Senior Research Scientist and Program Leader, Medical Research Council (MRC) Prion Unit, Imperial College School of Medicine, St. Mary's Hospital, London |
1999-2000 | Assistant Professor, Department of Microbiology and Immunology, University of Kentucky Assistant Professor, Program in Gerontology, University of Kentucky |
2000-2001 | Assistant Professor, Department of Neurology, University of Kentucky |
2001-2007 | Associate Professor , Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky Associate Professor, Department of Neurology, University of Kentucky Associate Professor - Faculty Affiliate, Graduate Center for Gerontology, University of Kentucky |
2002 - 2007 | Associate Professor, Sanders-Brown Center on Aging, University of Kentucky |
C. Honors and Awards
1991-1994 | NIH Postdoctoral Fellowship |
1996 -1997 | Alexander von Humboldt-Stiftung, German American Academic Council Foundation Research Award in Support of Young Scientists and Scholars from the United States and Germany |
1999 | University of Kentucky research challenge trust fund faculty (RCTF) appointee |
2005 | Faculty participant in the University of Kentucky - Shandong University ( China) faculty exchange program |
2005 - present | Honorary Visiting Professor, Institute of Biological Sciences and Technology, Beijing Jiaotong University, China |
2007 | Recipient of the Japan Society for the Promotion of Science (JSPS) Invitation Fellowship for Research in Japan |
D. Professional Societies
American Society for Microbiology
American Society for Cell Biology
American Association for the Advancement of Science
Federation of American Societies for Experimental Biology
American Society for Biochemistry and Molecular Biology
II. PROFESSIONAL ACTIVITIES
A. Review Activity, Funding Agencies (National and International) | |
2007 - present | Permanent full member of the Cellular and Molecular Neurodegeneration (CMND) Study Section, National Institutes of Health (NIH) |
2006 - 2007 | Member of the Neural Degenerative Disorders and Glial Biology Study Section, National Institutes of Health (NIH) |
2006 | Member of the Neural Oxidative Metabolism and Death Study Section, National Institutes of Health (NIH) |
2006 | Member of the Alzheimer's disease clinical scientist development "Markey" K08 award review committee |
2006 | Member of the ZRG1 IDM-Q (10) B Special Emphasis Panel Study Section |
2006 | Member of the United Kingdom Food Standards Agency (FSA) review panel of Transmissible Spongiform Encephalopathies (TSEs) Program |
2005 | Member of the NIH/National Institute of Allergy and Infectious Diseases (NIAID) Special Emphasis Panel Review Group ZAI1 ML-I (M1) to review Michael E. Lamm's unsolicited PO1 "Mucosal Immunity and Infection" |
2005 | Member of the Infectious Diseases and Microbiology IRG Center for Scientific Review Special Emphasis Panel ZRG1 IDM-B, National Institutes of Health (NIH) |
2004 | Member of the NIH/National Institutes on Aging (NIA) Special Emphasis Panel/Scientific Review Group 2005/01 ZAG1 ZIJ-7 (J1) to review Dr. Stanley Prusiner's P01 " Molecular Pathogenesis of Age-Dependent CNS Degeneration" , University of California, San Francisco |
2004 | Member of Special Emphasis Panel (BDCN-E 02) of the Brain Disorders and Clinical Neuroscience integrated review group, National Institutes of Health (NIH) |
2003 | Reviewer for the ZNS1 SRB-W (01) Fogarty Adults Special Emphasis Panel "Brain Disorders in the Developing World: Research across the Lifespan", National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH) |
2001- 2004 | Member of the Brain Disorders and Clinical Neuroscience's Study Section-3 (BDCN-3) , National Institutes of Health (NIH) |
2002 | Member of the United States Army Medical Research and Development Command, Program in Prion Research Study Section |
2002 | Member of Site Visiting Committee to review Dr. Stanley Prusiner's NIH National Institutes on Aging (NIA) Program Project Grant, ‘Novel therapeutics for prion diseases', University of California, San Francisco |
2002 | Member of the Site Visiting Committee to review future Biological Sciences Research Council (BBSRC) -sponsored TSE research at the Institute for Animal Health, UK |
2001 | Chair, Sub-committee to review Transmissible Spongiform Encephalopathies Programs: Biological Sciences Research Council (BBSRC) 2001 Institute Assessment Exercise |
2001 | Member of the Site Visiting Committee to review research at the Institute for Animal Health, UK, for allocation of the 2002-2006 Competitive Strategic Grant for the UK Biotechnology and Biological Sciences Research Council (BBSRC) 2001 Institute Assessment Exercise |
1999 | Member of the scientific advisory panel for the UK Ministry of Agriculture Food and Fisheries (MAFF) Transmissible Spongiform Encephalopathies (TSE) research and surveillance program |
1998-1999 | Member of the UK Biotechnology and Biological Sciences Research Council (BBSRC) biology of spongiform encephalopathies program (BSEP) research funding advisory panel |
1994-present | Ad hoc referee for the following funding agencies: US Alzheimer's disease and Related Disorders; National Institutes of Health (NIH); National Science Foundation (NSF); UK Medical Research Council (MRC); Comitato Promotore Telethon (Italy) research grants; Special Trustees for St Thomas' Hospital Research Endowments Committee; UK Biotechnology and Biological Sciences Research Council (BBSRC) UK Ministry of Agriculture Food and Fisheries (MAFF); Indiana Alzheimer Disease Center; UK Department of Health; Science Foundation Ireland; Alberta Agricultural Research Institute |
B. Membership of other scientific committees, advisory panels and consultancies | |
2006 - 2009 | Chair of the United States Food and Drug Administration (FDA) Transmissible Spongiform Encephalopathy Advisory Committee (TSEAC) |
2005 - 2006 | Member of the United States Food and Drug Administration (FDA) Transmissible Spongiform Encephalopathy Advisory Committee (TSEAC) |
2006 | Advisor to the European Commission Prion Strain Typing Expert Group |
2005 | Advisor to the World Health Organization (WHO) on Transmissible Spongiform Encephalopathies |
2005 | Member of the United States Food and Drug Administration (FDA) Center for Devices and Radiological Health advisory panel to address TSE decontamination studies for medical devices |
2004 - 2007 | Member of the United States Food and Drug Administration (FDA) Transmissible Spongiform Encephalopathy Advisory Committee (TSEAC) |
2004 - present | Member of the TSE task force, Kentucky Department of Agriculture |
2004 | Consultant to the Food and Drug Administration (FDA) Transmissible Spongiform Encephalopathy Advisory Committee (TSEAC) |
1999-2000 | Member of the steering committee for the UK Biotechnology and Biological Sciences Research Council (BBSRC) , Ministry of Agriculture Food and Fisheries (MAFF), Medical Research Council (MRC) and Department of Health sponsored Transmissible Spongiform Encephalopathies (TSE) workshop, April 2000 |
1996 | Ad Hoc committee member to provide information bearing on the risk of the transmission of Creutzfeldt-Jakob disease from the administration of blood, blood components, or blood derivatives: United States Food and Drug Administration (FDA) and the National Institutes of Health (NIH) National Heart, Lung and Blood Institute (NHLBI) |
1996-1999 | Member of the organizing committees for the 3rd, 4th and 5th Annual German-American Frontiers of Science Symposium: National Academy of Sciences (NAS), the Max-Planck-Society and the German American Academic Council (GAAC) |
2002 | Member of the committee to develop an NIH-Sponsored TSE Reagent Repository Workshop |
2001 | Member of the scientific advisory panel for the US Creutzfeldt-Jakob Disease Foundation |
2000- present | Member of the External Advisory Committee for the Indiana Alzheimer Disease Center |
2006 | Member of the vCJD Scientific Advisory Committee, ------------ |
2004 | Scientific consultant to ------------------------------------- |
2002 | Consultant, Scientific advisory meeting: proteasome inhibition and prion disease. -------- ------------------------------------------ |
2002 | Scientific consultant to -------------------------------------- |
2002 | Member of the CWD advisory panel, Kentucky Department of Fish and Wildlife Resources |
2001- present | Scientific consultant to -------------------------- |
2000 | Scientific consultant to the law firms of ---------------------------------------------------------- -------------------------------------------- |
2006 - 2007 | Scientific consultant to the law firm of ---------------------- |
1998 | Scientific consultant to the law firm of -------------------------------------------- Risks of infectivity of a TSE/BSE agent associated with proteins isolated from the milk of transgenic animals |
C. Editorial Responsibilities | |
2005 - present | Science - Board of Reviewing Editors |
2007 | Biochimica et Biophysica Acta - Guest Editor for the 'Prion-Related Disorders' issue of the Molecular Basis of Disease series |
2006 - present | Prion - Associate Editor |
2004 | Prions and Prion Diseases: Current Perspectives. Glenn C. Telling (Ed.) Horizon Scientific Press, Wymondham UK |
D. Ad hoc journal reviewing | |
On average, 10 to 12 additional manuscripts reviewed per year Science; Nature ; Nature Medicine ; EMBO Journal ; Journal of General Virology ; Neurology; Molecular Reproduction; Brain Research; Journal of the Royal College of Physicians of London; Journal of Clinical Pathology; Journal of Neurochemistry; Royal Society Proceedings: Biological Sciences; Neuroscience Letters; Molecular Medicine Today; American Journal of Pathology; Trends in Neurosciences; Lancet; Biochemistry; Trends in Cell Biology; Proceedings of the National Academy of Sciences (PNAS); Trends in Microbiology; Journal of Biological Chemistry; Neuropathology and Applied Neurobiology; Journal of Neuroscience; Journal of Thrombosis and Haemostasis; Molecular Brain Research; FEBS Letters; Journal of Virology; Lancet, Neurology; PLOS Pathogens; Annals of Neurology; Nature Neuroscience; Molecular Biology of the Cell; Journal of Pathology |
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E. Organization of workshops and meeting sessions | |
1997 | National Academy of Sciences (NAS), Max-Planck-Society and the German American Academic Council's 3rd Annual German-American Frontiers of Science Symposium, Munich, Germany |
1998 | National Academy of Sciences (NAS) and the German American Academic Council's 4th Annual German-American Frontiers of Science Symposium, Irvine. California |
1999 | National Academy of Sciences (NAS) and the German American Academic Council's 5th Annual German-American Frontiers of Science Symposium: Potsdam, Germany |
2000 | Biotechnology and Biological Sciences Research Council (BBSRC) Biology of Spongiform Encephalopathies (BSEP) Workshop , Keele, UK |
2005 | Second International Chronic Wasting Disease Symposium, Madison, Wisconsin |
III. EDUCATIONAL ACTIVITIES
A. Courses Taught | |
2005 | GEO475G Medical Geography |
2007 - present | Instructor, MI710-02 Mechanisms of Microbial Pathogenesis |
2004 - present | Instructor, MI615: Molecular Biology |
2004 - present | Instructor, MI710-002: Molecular Virology |
2000 - 2003 | GRN650, Research Methods in Gerontology (Course Director) |
1999 - present | GRN650, Research Methods in Gerontology, Transgenic methods in aging research |
2000 - present | Instructor, MI822: Infection, Immunity and Disease Lectures: Viral Genetics; Prions and Diseases Dicussion Groups: Childhood Viral Diseases; Vector-borne viruses |
1999 | PGY618: Molecular Neurobiology, Prions and Prion Diseases |
2000 - present | MI772, Seminar in Microbiology |
2002 | Organizer of the Cellular and Molecular Mechanisms of Neurodegenerative Diseases Journal Club |
2007 - present | Organizer of the Microbiology, Immunology and Molecular Genetics Departmental Prion Diseases Journal Club Mentored MI772 Students (Seminar in Microbiology) - ----------------- (2000) ; ------------- ---------- (2007) |
2005 | Medical School of Shandong University, China - Course on Prions and Prion diseases for medical students |
Prior to the University of Kentucky | |
1997 | Visiting lecturer, University of California, Berkeley |
1997 | Visiting lecturer, University Pacific School of Dentistry, San Francisco |
1996 - 1997 | Organizing teaching seminars for a group that included 20 postdoctoral fellows, Department of Neurology, University of California, San Francisco |
1998 | Lecturer, B.Sc. Clinical Sciences and M.Sc. Molecular Genetics, Imperial College School of Medicine, St. Mary's Hospital, London |
B. Previously mentored Research Fellows and Associates | |
1996 - 1997 | -----------------. - Postdoctoral Fellow, University of California, San Francisco |
1996 - 1997 | ------------------ - Research Associate, University of California, San Francisco |
1997 - 1999 | ----------------- - Research Associate, MRC Prion Unit London |
1997 - 1999 | ----------------- - Research Associate, MRC Prion Unit London |
1999 - 2001 | ------------------ - Research Associate, University of Kentucky |
2001 | ------------------- - Postdoctoral Fellow, University of Kentucky |
2002 - 2005 | --------- - Postdoctoral Fellow, University of Kentucky |
2002 - 2003 | ------------, Associate Professor, Laboratory of Molecular Biology, Shandong University School of Medicine - Visiting Scientist, University of Kentucky |
2001 - 2003 | --------------- - Research Associate, University of Kentucky |
C. Previously mentored Graduate Students Graduate Degree/Date Thesis title Current position |
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------------------ MS (2001) -------------------------------- -------------------------------------------- --------------------------- ------------------------------ -------------------------------------------- ----- |
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---------------- PhD (2005) -------------------------- --------------------------------------------- ------------------ -------------------------------------- --------------------------------------- --------------------------------- --------------------------- ----------------------------- |
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---------------- PhD (2005) --------------------------------------- ------------------------------------------- ---------------------------------------------------------------------------------- -------------------------------------- ------------------------------------ -------------------------------------- | |
-------------- MS (2003) ---------------------- ----------- | |
D. Rotation project advisor | |
------------------------- ---------------------- ----------------------- -------------------------- -------------------- --------------------- --------------- -------------------------- ----------------------- ---------------------- ------------------------- ---------------------- ---------------------- --------------- ---------------- -------------------- ----------------------- ------------------------ ---------------- --------------------- ----------------- --------------------------- ------------------------ -------------------------- ----------------------------- ---------------- ---------------------- -------------------------- --------------------------- ------------- | |
E. Current Graduate Students | |
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F. Current Postdoctoral Fellows and Research Staff | |
2005 - present | ------------------------------------ |
2006 - present | ----------------------------------- |
2002 - present | ------------------------------------ |
2005 - present | -------------------------------------- |
2006 - present | --------------------------------- |
2006 - present | ------------------------------------ |
G. Other graduate student committees at University of Kentucky | |
2002 - 2005 | ------------------------------------------------------------------------------------- |
2002- 2004 | ------------------------------------------------------------------------------------- |
2002- 2006 | ------------------------------------------------------- |
2006 | --------------------------------------------------- |
2006 | -------------------------------------------------- |
2006 | -------------------------------------------------------------------- |
2006 - present | ------------------------------------------------------------------- |
H. External Thesis Committees | |
1997-2001 | ------------------------------ College of Veterinary Medicine and Biomedical Sciences, Department of Pathology, Colorado State University |
2002- 2006 | ---------------------------- University of Rochester , Center for Aging and Developmental Biology , Division of Gene Therapy and Molecular Medicine |
I. Mentored Undergraduate and High School Students | |
2003 | ------------------ University of Kentucky - "Bucks for Brains" research student advisor |
2006 - 2007 | -----------------, Agricultural Biotechnology Research Mentor |
2007 | ---------------- |
IV. UNIVERSITY SERVICE
2004 | Chair, Cellular and Molecular Biology of Prion Diseases Faculty Search Committee |
2002 | Chair, Search Committee for Chair of the Department of Physiology |
2001- 2003 | Chair, Recruitment Committee, Graduate Program in Gerontology |
2000 | Chair, Ad hoc committee to review research proposals for the Spinal Cord and Brain Injury Research Center, College of Medicine |
2007 - 2010 | Member of the University of Kentucky Senate |
2006 - 2007 | University of Kentucky Vice President for Research Search Committee |
2006 - present | Microbiology, Immunology and Molecular Genetics Education, Practice and Policies Committee |
2006 - present | College of Medicine Dean's Research Advisory Affairs Group (RAAG) |
2005 - 2006 | Department of Internal Medicine Six Year Review Committee |
2006 | College of Medicine, Ad hoc promotion and tenure advisory committee |
2005 - 2006 | Gerontology faculty search committee |
2005 - 2008 | Professional Code Committee |
2005 - present | Transgenic Facility Oversight Committee |
2004 - present | University Mouse Focus Group |
2003 - present | University Research Advisory Committee |
2004 - 2007 | Administrative Council for the Program in Gerontology |
2002 - 2005 | Institutional Biosafety Committee |
2001- 2004 | Steering Committee, Graduate Program in Gerontology |
2002 | Planning Committee to establish a Regional Center of Excellence in Emerging Diseases at the University of Kentucky |
2000 - 2001 | Recruitment Committee, Graduate Program in Gerontology Imperial College School of Medicine, London |
1997-1999 | Division of Neuroscience representative, Computer Users Consultative Committee University of California, San Francisco |
1994-1996 | Co-ordination of scientific aspects of Licensing and Research Agreement:----------------- ---------------------------- ------------------------- ---------------------------------- ----------------------------- |
1994-1997 | Producing Patent Applications in liaison with patent lawyers and the University Of California Office Of Technology Transfer |
1994-1997 | Co-ordination of scientific and budgetary aspects of extra-mural grants and non-competitive grant renewals |
1996-1997 | Co-ordination of Annual Progress Reports for -------------------- ------------------------------------- ------------------------ ----------------------------------------- ----------------------------------- |
1997 | Planning Committee for Annual Review of ------------------ ------------------------ ------------------------- --------------------- ----------------------- |
V. RESEARCH ACTIVITIES
A. Active Support | |
2002 - 2009 | N01-AI-25491 Co-Principal Investigator (30 % effort) US Based Collaboration in Emerging Viral and Prion Diseases NIAID/NIH $2,634,349 |
2005 - 2010 | 2RO1 NS040334-04 Principal Investigator (40 % effort) Transgenetic studies of prion disease in cervids NINDS/NIAID/NIH $1,678,035 |
2002 - 2007 | V180003 Co-Investigator ( 10 % effort) Genetic susceptibility and biological characterization of CWD United States Department of Defense (DoD) $ 743,282 |
2006 - 2011 | 58-5348-6-131 Principal Investigator (0 % effort) Specific Cooperative Agreement U.S. Department of Agriculture (USDA) Agricultural Research Service $425,000 |
2007 - 2009 | Principal Investigator ( 5 % effort) Specific Cooperative Agreement U.S. Department of Agriculture (USDA) Agricultural Research Service $ 78 ,0 49 |
2006 - 2007 | T32 AI49795 Training Faculty Member (for Kristi Green) Training Program in Microbial Pathogenesis NIH $18,156/year |
2007 - 2008 | T32 DA022738 Training Faculty Member (for Rachel Angers) Therapeutic Strategies for Neurodegeneration NIH $25,370/year |
B. Previous Support | |
2002 - 2005 | Agreement with Institute of Animal Health to make transgenic mice $120,834 |
2001 - 2003 | 3 R01 NS40334-02S1 Principal Investigator Transgenetic studies of prion disease in cervids (Supplement) NINDS/NIAID/NIH $750,000 |
2003 | Agreement with ------------------- ------------- |
2000 - 2001 | ------------ Principal Investigator ----------------------------- --------------------------- ---------------------------- ------------------------------- --------------------------------- ------------- |
2001 - 2006 | T32 AI49795 Training Faculty Member (for Shawn Browning) Training Program in Microbial Pathogenesis NIH $18, 156/year |
1999 - 2000 | Principal Investigator NIH Academic Leadership Award and the Office of the Vice Chancellor for Research and Graduate Studies for the University of Kentucky Medical Center $15, 000 |
2002 - 2004 | Training Faculty Member (for Michael Jernigan) Molecular and Cellular Aspects of Brain Aging NIA/NIH $19, 656/year |
1997 - 2002 | Principal Investigator --------------------------- ------------------- |
C. Publications
- Telling, Glenn C. "Transgenic mice for bioassay of prions from deer or elk with chronic wasting disease" United States Patent Application, provisional application submitted to US Patent Office, November 2005
- Telling, Glenn C. and Rodney Guttmann "Calpains as targets for inhibition of prion disease"
- United States Patent Application 20060234971, October 2006
- Prusiner, Stanley B; Glenn C. Telling; Fred E Cohen; Michael R. Scott "Recombinant Construct Encoding Epitope Tagged PrP Protein"
- United States Patent 6,602,672. Issued August 5, 2003
- Prusiner, Stanley B; Glenn C. Telling; Fred E Cohen; Michael R. Scott "Transgenic animals expressing artificial epitope-tagged proteins"
- United States Patent 5,789,655. Issued August 8, 1998
- United States Patent 6,150,583. Issued November 21, 2000
- Prusiner, Stanley B.; Michael R. Scott; Glenn C. Telling " Detecting cow, sheep and human prions in a sample and transgenic mice used for same"
- United States Patent 6,008,435. Issued December 28, 1999
- Prusiner, Stanley B.; Michael R. Scott; Glenn C. Telling "Method of detecting prions in a sample and transgenic animal used for same"
- United States Patent 5,763,740. Issued June 9, 1998
- United States Patent 5,908,969. Issued June 1, 1999
- Prusiner, Stanley B.; Michael R. Scott; Glenn C. Telling "Detecting prions in a sample and prion preparation and transgenic animal used for same"
- United States Patent 5,792,901. Issued August 11, 1998.
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- Telling, G.C. Editorial: Prion-related disorders. Biochimica et Biophysica Acta, 1772(6): 597, 2007
- Kurt , Timothy D., Matthew R. Perrott, Carol J. Wilusz, Jeffrey Wilusz, Surachai Supattapone, Glenn C. Telling, Mark D. Zabel and Edward A. Hoover . Efficient In Vitro Amplification of Chronic Wasting Disease PrPres. J. Virol. 81(17):9605-8, 2007
- Nazor, Karah E ., Tanya Seward and Glenn C. Telling Novel behavioral motor and neuropathological deficits in mice deficient for prion protein. Biochimica et Biophysica Acta, 1772(6): 645-653, 2007
- Candace K. Mathiason, Jenny G. Powers, Sallie J. Dahmes, David A. Osborn, Karl V. Miller, Robert J. Warren, Gary L. Mason, Sheila A. Hays, Jeanette Hayes-Klug, Davis M. Seelig, Margaret A. Wild, Lisa L. Wolfe, Terry R. Spraker, Michael W. Miller, Christina J. Sigurdson, Glenn C. Telling, and Edward A. Hoover. Infectious Prions in the Saliva and Blood of Deer with Chronic Wasting Disease. Science, 314: 133-6, 2006.
- Angers, Rachel C., Shawn R. Browning, Tanya S. Seward, Christina J. Sigurdson, Michael W. Miller, Edward A. Hoover and Glenn C. Telling. Prions in Skeletal Muscles of Deer with Chronic Wasting Disease. Science, 311: 1117, 2006.Featured article in Science Express
- Bian, Jifeng , Karah E. Nazor, Rachel Angers, Michael Jernigan, Tanya Seward, Adrian Centers, Michael Green and Glenn C. Telling. GFP-tagged PrP supports compromised prion replication in transgenic mice. Biochem. Biophys. Res. Comm, 340: 894-900, 2006
- Telling, Glenn C. Study of prion types questions classification system. The Lancet Neurology , 4: 1-2, 2005
- Telling, Glenn C. Anchors away: Of plaques and pathology in prion disease. N. Engl. J Med., 353(11): 1177-1179, 2005.
- Nazor, Karah E ., Franziska Kuhn, Tanya Seward, Mike Green, Daniel Zwald, Mario Pürro, Jaqueline Schmid, Karin Biffiger, Aisling M. Power, Bruno Oesch, Alex J. Raeber and Glenn C. Telling. Immunodetection of disease-associated mutant PrP which accelerates disease in GSS transgenic mice. EMBO Journal , 24(13): 2472-2480, 2005.
- Browning, Shawn R., Gary L. Mason, Tanya Seward, Mike Green, Gwyneth A. J.Eliason, Candace Mathiason, Christina Sigurdson, Michael W. Miller, Elizabeth S. Williams, Ed Hoover and Glenn C. Telling. Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP. J. Virol. 78(23) : 13345-13350, 2004
- Moroncini G, Kanu N, Solforosi L, Abalos G, Telling GC, Head M, Ironside J, Brockes JP, Burton DR, Williamson RA. Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc. Proc. Natl. Acad. Sci. USA , 101(28): 10404-10409, 2004
- Yadavalli, Rajgopal , Rodney P. Guttmann, Tanya Seward, Adrian P. Centers, R. Anthony Williamson and Glenn C. Telling. Calpain-dependent endoproteolytic cleavage of PrPSc modulates PrPSc accumulation and prion propagation in scrapie infected cells. J. Biol. Chem., 279(21):21948-56, 2004
- Telling, Glenn C. The mechanism of prion strain propagation. Genome Biology, 5(5):222.1-222.3, 2004
- Korth, C ., Kiyotoshi Kaneko, Darlene Groth, Norbert Heye, Glenn Telling, James Mastrianni, Piero Parchi, Pierluigi Gambetti, Robert Will, James Ironside, Cornelia Heinrich, Patrick Tremblay, Stephen J. DeArmond and Stanley B.Prusiner. Abbreviated incubation times for human prions in mice expressing a novel chimeric prion protein transgene. Proc. Natl. Acad. Sci. USA , 100 (8): 4784-4789, 2003
- Connolly, John G., Roth J. Tate, Glenn C. Telling, Jan Fraser, Debbie Brown and Mark W. Head. Properties of the cellular prion protein expressed in Xenopus oocytes. Neuroreport, 13 (9): 1229-1233, 2002
- Bosque, Patrick J., Chongsuk Ryou, Glenn Telling, David Peretz, Giuseppe Legname, Stephen J. DeArmond and Stanley B. Prusiner. Prions in skeletal muscle. Proc. Natl. Acad. Sci. USA , 99: 3812-3817, 2002
- Mastrianni, J. A., S. Capellari, G. C. Telling, D. Han, P. Bosque, S. B. Prusiner, and S. J. DeArmond . Inherited prion disease caused by the V210I mutation: Transmission to transgenic mice. Neurology, 57: 2198-2205, 2001.
- Telling, Glenn C. Protein-based PCR for prion diseases? Nature Medicine, 7(6): 11-12, 2001
- Telling, Glenn C. Transgenic studies of prion diseases. Methods in Molecular Medicine, 58: 111-128, 2001 (Invited Review)
- Campbell, Susan, Ulla Dennehy and Glenn Telling. Analyzing the influence of PrP primary structure on prion pathogenesis in transgenic mice. Archives of Virology[Suppl], 16 : 87-94, 2000
- Telling, G.C. , Prion protein genes and prion diseases: studies in transgenic mice. Neuropath. Appl. Neurobiol, 26: 209-220, 2000
- Mastrianni, James A., Randal Nixon, Robert Layzer, Glenn C. Telling, Dong Han, Stephen J. DeArmond, Stanley B. Prusiner. Prion protein conformation in a patient with sporadic fatal insomnia. N. Engl. J. Med., 340:1630-1638, 1999
- Telling, Glenn C. Prion diseases . Horizons in Medicine, 10: 415-428,1999
- Fisher, Elizabeth, Glenn Telling and John Collinge. Prions and the prion disorders. Mammalian Genome, 9, 497-502, 1998
- Westaway, David, Glenn Telling, and Suzette Priola. Prions. Proc. Natl. Acad. Sci. USA ., 95: 11030-11031, 1998
- Scott, Michael R ., Jiri Safar, Glenn Telling, Oanh Nguyen, Darlene Groth, Marilyn Torchia, Ruth Koehler, Patrick Tremblay, Dirk Walther, Fred E. Cohen, Stephen J. DeArmond, and Stanley B. Prusiner. Identification of a prion protein epitope modulating transmission of BSE prions to transgenic mice. Proc. Natl. Acad. Sci. USA ., 94: 14279-14284, 1997
- Telling, Glenn C ., Patrick Tremblay, Marilyn Torchia, Stephen J. DeArmond, Fred E. Cohen and Stanley B. Prusiner. N-terminally tagged prion protein supports prion propagation in transgenic mice. Protein Science, 6: 825-833, 1997
- Muramoto, Tamaki, Stephen J. DeArmond, Michael Scott, Glenn C. Telling, Fred E. Cohen and Stanley B. Prusiner. Heritable neuronal storage disease in mice expressing prion protein with deletion of an α-helix. Nature Medicine, 3: 750-755, 1997
- Bamborough, P ., H. Wille, G. C. Telling, F. Yehiely, S. B. Prusiner and F. E. Cohen. Prion protein structure and scrapie replication: theoretical, spectroscopic and genetic investigations. Cold Spring Harbor Laboratory Symposium, 61, 495-509, 1997
- Telling, Glenn C ., Piero Parchi, Stephen J. DeArmond, Pietro Cortelli, Pasquale Montagna, Ruth Gabizon, James Mastrianni, Elio Lugaresi, Pierluigi Gambetti and Stanley B. Prusiner. Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science, 274: 2079-2082, 1996
- Telling, Glenn C ., Takeshi Haga, Marilyn Torchia, Patrick Tremblay, Stephen J. DeArmond and Stanley B. Prusiner. Interactions between wild type and mutant prion proteins modulate neurodegeneration in transgenic mice. Genes and Development, 10:1736-1750, 1996
- Gabizon, Ruth, Glenn Telling, Zeev Meiner, Michele Halimi, Irit Kahana and Stanley B. Prusiner. Different properties of mutant and wild-type PrP proteins in heterozygous patients with Creutzfeldt-Jakob disease. Nature Medicine, 2: 59-64, 1996
- Telling, G ., M. Scott and S. B. Prusiner: Transgenetics and Gene Targeting in Studies of Prion Diseases. Frontiers in Endocrinology, 16, 237-266, 1996
- Prusiner, S.B ., G. Telling, F. E. Cohen and S. J. DeArmond. Prion Diseases of Humans and Animals. Seminars in Virology, 7: 159-173, 1996
- Scott, M. R. D ., G. C. Telling and S. B. Prusiner: Transgenetics and gene targeting in studies of prion diseases. Current Topics in Microbiology and Immunology, 207, 95-123, 1996
- Telling, Glenn C ., Michael Scott, James Mastrianni, Ruth Gabizon, Marilyn Torchia, Fred E. Cohen, Stephen J. DeArmond and Stanley B. Prusiner. Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell, 83: 79-80, 1995
- Williams, J ., M. Williams, C. Liu and G. Telling: Assessing the role of E1A in the differential oncogenicity of Group A and Group C Human Adenoviruses. Current Topics in Microbiology and Immunology, 199, 149-175, 1995
- Telling, Glenn C ., Michael Scott, Karen K. Hsiao, Dallas Foster, Shu-Lian Yang, Marilyn Torchia, Katie C. L. Sidle, John Collinge, Steven J. DeArmond and Stanley B. Prusiner. Transmission of Creutzfeldt-Jakob Disease from Humans to Transgenic Mice Expressing Chimeric Human-Mouse Prion Protein. Proc. Natl. Acad. Sci.USA ., 91: 9936-9940, 1994
- Carlson, G.A ., C. Ebeling, S-L. Yang, G. Telling, M. Torchia, D. Groth, D. Westaway, S. J. DeArmond and S. B. Prusiner. Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice. Proc. Natl. Acad. Sci. USA ., 91: 5690-5694, 1994
- Telling, G. C. and J. Williams. Constructing chimeric type 12/type 5 adenovirus E1A genes and using them to identify an oncogenic determinant of adenovirus type 12. Journal of Virology, 68: 877-887, 1994
- Telling, G. C ., S. Periera, M. Szatkowski-Ozers and J. Williams. Absence of an essential regulatory influence of the adenovirus E1B 19-kilodalton protein on viral growth and early gene expression in human diploid WI38, HeLa and A549 cells. Journal of Virology, 68: 541-547, 1994
- Borchelt, D. R ., M. Rogers, N. Stahl, G. Telling and S. B. Prusiner. Release of the cellular prion protein from cultured cells after loss of its glycoinositol anchor. Glycobiology, 3: 319-329, 1993
- Telling, G. C. and J. F. Williams. The E1B 19kDa protein is not essential for transformation of rodent cells in vitro by adenovirus type 5. Journal of Virology, 67: 1600-1611, 1993
- Hayes, B. W ., G. C. Telling, M. M. Myat, J. F. Williams and S. J. Flint. The adenovirus L4 100 kilodalton protein is necessary for efficient translation of viral late mRNA species. Journal of Virology, 64: 2732-2742, 1990
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- Nazor, Karah E. and Glenn C. Telling. Transgenetic models of prion replication. In: Handbook of Laboratory Animal Science, Second Edition, Animal Models Volume III Jann Hau (Ed.) CRC Press London, pp. 113 - 127, 2004
- Nazor, Karah E . and Glenn C. Telling. Transgenic Mouse Models of Prion Diseases. In: Prions and Prion Diseases: Current PerspectivesGlenn C. Telling (Ed.) Horizon Scientific Press, UK, pp. 121-144, 2004
- Prusiner SB, Baron H, Carlson G, Cohen FE, DeArmond SJ, Gabizon R, Gambetti P, Hope J, Kitamoto T, Laplanche J-L, Tateishi J, Telling G, Weissmann C and Will R. Report on Prions. In: Virus Taxonomy: The Classification and Nomenclature of Viruses. The Seventh Report of the International Committee on Taxonomy of Viruses M.H.V. van Regenmortel, C.M. Fauquet, D.H.L. Bishop, E.B. Carstens, M.K.Estes, S.M. Lemon, J. Maniloff, M.A. Mayo, D.J. McGeoch, C.R. Pringle, R.B. Wickner (Eds). Academic Press, San Diego California, pp 1032-1039, 2000
- Telling, Glenn C. Prion diseases of Humans and Animals. In: Viral Ecology, Christon J. Hurst (Ed.) Academic Press, pp. 593-619, 2000
- Telling, Glenn C. and John Collinge. Transmissible spongiform encephalopathies of Humans and Animals. In: Infectious diseases, Donald Armstrong and Jonathan Cohen (Eds.) Mosby International, Volume 1, Section 2, pp 19.1-19.6, 1999
- Telling, Glenn C. Prions. In: Everything you need to know about old age psychiatry…, Robert Howard (Ed.) Wrightson Biomedical Publishing Ltd, pp. 73-89, 1999
- Gabizon, Ruth, Glenn Telling, Zeev Meiner, Michele Halimi, Irit Kahana and Stanley B. Prusiner. Properties of the prion proteins in Creutzfeldt-Jakob disease patients heterozygous for the E200K mutation. In: Prions and Brain Diseases in Animals and Humans. Morrison, D. R. O. (Ed) Plenum Press, New York, New York, pp. 225-243,1998
- Prusiner, S. B ., Kaneko, K ., Vey, M ., Telling, G ., Scott, M ., Gabizon, R ., Taraboulos, A ., DeArmond, S. J., Cohen, F. E.: Molecular biology of prion propagation. In: Prions and Brain Diseases in Animals and Humans . Morrison, D. R. O. (Ed) Plenum Press, New York, New York, pp. 305-306 , 1998
- Telling, Glenn C ., Michael Scott and S. B. Prusiner: Deciphering prion diseases with Transgenic Mice. In: Bovine Spongiform Encephalopathy: The BSE Dilemma. Clarence J. Gibbs Jr. (Ed.) Springer Verlag, New York, pp. 202-231, 1996
- Gabizon, Ruth, Glenn Telling, Zeev Meiner, Michele Halimi, Irit Kahana and Stanley B. Prusiner. Altered properties of prion proteins in Creutzfeldt-Jakob disease patients heterozygous for the E200K mutation. In: Transmissible Subacute Spongiform Encephalopathies: Prion Diseases. L. Court and E. Dodet (Ed) Elsevier, Paris, pp. 199-205, 1996
- Telling, Glenn C. Bovine Spongiform Encephalopathy. Encyclopedia Americana, Grolier Inc ., Danbury, Connecticut, 2003
- Telling, Glenn C. Modeling prion transmission barriers using transgenic and in vitro approaches". NeuroPrion CWD Workshop, Edinburgh, UK, September 2007
- Angers, R.C., S.R. Browning, T.S. Seward, M.W. Miller, A. Balachandran, D. McKenzie, E.A. Hoover, G.C. Telling. C haracterization of CWD prion strains using transgenic mice. Prion 2007 : Edinburgh, UK, September 2007
- Green, K.M., J. Castilla, T.S. Seward, C. Soto, G.C. Telling . Accelerated studies of interspecies prion transmission using combined transgenic and PMCA technologies. Prion 2007 : Edinburgh, UK, September 2007 (Platform presentation for K. Green)
- Nunn, Michael, Kenneth Tyler, Glenn Telling, Christine Zink, and Eugene Major. Emerging and Re-emerging viral infections of the human nervous system: What we know from the past and what we need to know for the future. 40th Winter Conference on Brain Research, Snowmass, CO, January 2007
- K.M. Green, S.R. Browning, T.S. Seward, M. Green, E.A. Hoover, G.C. Telling. Interspecies prion transmission is controlled by conformational compatibility of PrPSc and heterotypic PrPC. PRION2006- Strategies, advances and trends towards protection of society, Turin, Italy, October 2006 (Platform presentation for K. Green)
- R.C. Angers, S.R. Browning, T.S. Seward, C.J. Sigurdson, M.W. Miller, E.A. Hoover, G.C. Telling. Prions in Skeletal Muscle of CWD Infected Deer . PRION2006- Strategies, advances and trends towards protection of society, Turin, Italy, October 2006
- Telling, Glenn C., Kristi Green and Rachel Angers. Deciphering mechanisms of prion transmission using transgenic mice . 10th International Symposium for Zoonosis Control - Protection of Society from Infectious Threat , Sapporo, Japan, August 2006
- Browning, Shawn R., Kristi Green, Tanya Seward, and Glenn C. Telling. Transgenic mouse models of chronic wasting disease. IBC's Second Annual Transmissible Spongiform Encephalopathies (TSEs) meeting - Science and strategies to detect and control infectivity in biopharmaceuticals and blood products, Reston, VA, November 2005
- Telling, Glenn C., Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP. National Institute of Toxicological Research International Symposium, Seoul, Korea, October 2005
- Telling, Glenn C. Transgenic mouse models of animal and human prion diseases - insights into the mechanisms of prion replication, species barriers and prion strains. Proceedings of the International Symposium on Advanced Virology, Beijing, China, October 2005
- Telling, Glenn C. , Shawn R. Browning, Kristi Green, Rachel Angers, Gary L. Mason, Tanya Seward, Mike Green, Gwyneth A. J. Eliason, Candace Mathiason and Ed Hoover. Transgenetic studies of chronic wasting disease - an overview. International Conference: "Prion 2005 - Between fundamentals and society's needs" Düsseldorf, Germany, October, 2005
- Telling, Glenn C. Overview on progress in detecting and quantifying prion infectivity by bioassay in transgenic mice. World Health Organization (WHO) Consultation on Tissue Infectivity Distribution in Transmissible Spongiform Encephalopathies, WHO Headquarters, Geneva, September 2005
- Browning, Shawn R., Kristi Green, Gary L. Mason, Tanya Seward, Mike Green, Gwyneth A. J. Eliason, Candace Mathiason, Ed Hoover and Glenn C. Telling. Transgenic mouse models for studying chronic wasting disease. Second International Chronic Wasting Disease Symposium, Madison, Wisconsin, July 2005
- Telling, Glenn C., Shawn Browning and Karah E. Nazor. Transgenic models of prion replication. 2nd International Symposium "The New Prion Biology: Basic Science, Diagnosis and Therapy", Venice, Italy, April 2005
- Nazor, Karah E ., Franziska Kuhn, Tanya Seward, Mike Green, Daniel Zwald, Mario Pürro, Jaqueline Schmid, Karin Biffiger, Bruno Oesch, Alex J. Raeber and Glenn C. Telling. Transgenic studies of Gerstmann-Sträussler-Scheinker prion pathogenesis. Molecular Mechanisms of Transmissible Spongiform Encephalopathies (Prion Diseases), Snowbird, Utah, January, 2005
- Peretz, David , Melissa Michelitsch, Carol Gao, Xuemei Wang, Alex Gyenes, Robert Shimizu, John Hall, Xue Wu, Glenn C. Telling, Bruce Phelps, David Chien and Celine Hu. Studies on Detecting Infectious Prions (PrPSc) Spiked in Human Blood Products. Molecular Mechanisms of Transmissible Spongiform Encephalopathies (Prion Diseases), Snowbird, Utah, January, 2005
- Browning, Shawn R., Karah Nazor, Tanya Seward and Glenn C. Telling. Transgenic models of prion replication. 44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Washington , DC , October 30 - November 2, 2004
- Browning, Shawn R., Gary L. Mason, Tanya Seward, Mike Green, Gwyneth A. J. Eliason, Candace Mathiason, Ed Hoover and Glenn C. Telling. Transgenic model for chronic wasting disease. Animal Prion diseases and the Americas, Ames, Iowa, October 2004
- Nazor, Karah E ., Franziska Kuhn, Tanya Seward, Mike Green, Daniel Zwald, Mario Pürro, Jaqueline Schmid, Karin Biffiger, Bruno Oesch, Alex J. Raeber and Glenn C. Telling. Transgenic studies of Gerstmann-Sträussler-Scheinker prion pathogenesis. Animal Prion diseases and the Americas, Ames, Iowa, October 2004
- Connolly, John G., Roth J. Tate, Glenn C. Telling, Jan Fraser, Debbie Brown, Neil McLennan and Mark W. Head. Cellular prion protein expressed in Xenopus oocytes. The Scottish Neuroscience Group, University of Strathclyde, 2004.
- Telling, Glenn C. Transgenic approaches for studying Chronic Wasting disease, Center for Food and Nutrition Policy Forum: Transmissible Spongiform Encephalopathies in Animal and Human Health: The Science and the Policy, Virginia Tech, March 2004
- Moronconi, G, N. Kanu, L. Solforosi, G. Albaso, G. Telling, J.P. Brokes, R. A. Williamson. Motif-grafted antibodies containing the replicative interface of PrP are specific for PrPSc. International Prion Conference: From Basic Research to Intervention Concepts, München - Germany, October 2003
- Yadavalli, Rajgopal , Rodney P. Guttmann, Adrian P. Centers, Tanya Seward, R. Anthony Williamson and Glenn C. Telling. Prion propagation is a calpain-dependent process. International Prion Conference: From Basic Research to Intervention Concepts, München - Germany, October 2003
- Telling, Glenn C. An Update on chronic wasting disease and other prion diseases. Food Research Institute Annual Meeting, Madison WI, May 2003
- Centers, Adrian, Michael Jernigan and Glenn Telling. Hybrid green fluorescent-prion proteins for monitoring PrPSc production and localization in prion infected cells. TSE diseases, Keystone Symposium, Brekenridge, CO, April 2003
- Telling, Glenn . Prion Diseases - Overview of General Concepts. Chronic Wasting Disease Symposium, Denver, CO, August 2002
- Browning, Shawn, Tanya Riddle and Glenn Telling. Production and Preliminary Characterization of Transgenic Mice for studying Chronic Wasting Disease. Chronic Wasting Disease Symposium, Denver, CO, August 2002
- Browning, Shawn, Tanya Riddle and Glenn Telling. Transgenic studies of Chronic Wasting Disease, a prion disease of Cervids. American Society for Virology 21st Annual Meeting, University of Kentucky, Lexington, KY, July 2002
- Nazor, Karah E ., Aisling Power, Tanya Riddle, and Glenn Telling. Transgenic and in vitro studies of GSS prion pathogenesis and propagation. American Society for Virology 21st Annual Meeting, University of Kentucky, Lexington, KY, July 2002
- Telling, Glenn and Adrian Centers. Hybrid green fluorescent-prion proteins for monitoring PrPSc production and localization in prion infected cells. American Society for Virology 21st Annual Meeting, University of Kentucky, Lexington, KY, July 2002
- Telling, Glenn and Adrian Centers. Hybrid green fluorescent-prion proteins for monitoring PrPSc production and localization in prion infected cells. American Federation for Aging Research 15th Annual Grantee Conference, New York, NY, April 2002
- Connolly, John G ., Roth J. Tate, Glenn C. Telling, Jan Fraser, Debbie Brown and Mark W. Head Properties of the cellular prion protein expressed in Xenopus oocytes. Biochemical Society Meeting, Herriot-Watt University, Edinburgh, April 2002
- Connolly, J.G ., R.J. Tate, G.C. Telling , and. M.W. Head. Non-isotopic detection of cellular prion protein expressed in Xenopus oocytes . Society Neurosciences Meeting, San Diego, November 2001
- Telling, Glenn C. Studying human prion diseases in transgenic mice. First Conference of the Creutzfeldt-Jakob Disease Foundation, Inc ., Miami, Florida, May 2000
- Telling, Glenn C. Perspectives on the use of transgenic mice. Biotechnology and Biological Sciences Research Council (BBSRC) Biology of Spongiform Encephalopathies (BSEP) Workshop , Keele University, UK, April 2000
- Dennehy, Ulla, Susan Campbell and Glenn C. Telling . Transgenic studies of prion transmission barriers. International symposium on the characterization and diagnosis of prion diseases in animals and man, Tubingen, Germany, T8, p17, 1999
- Telling, Glenn C . Prion strains and species barriers: Investigating Creutzfeldt Jakob disease, BSE and other prion diseases in transgenic mice. 13th International Conference on Lymphoid Tissues in Immune Reactions, Geneva, Switzerland, August 1999
- Telling, Glenn C. Bovine Spongiform Encephalopathy in the United Kingdom and the relationship with the new variant of Creutzfeldt-Jakob Disease in humans: An Update. XVIII Summer Course at Universidad del Pais Vasco/Euskal Herriko Unibersitatea, San Sebastian, Spain, July 1999
- Telling, Glenn C. Transgenic mouse models of prion disease. Neurobiology of Aging, 19 [Suppl.]: 885, 1998
- Telling, Glenn C . Insights into the mechanisms of prion propagation from Transgenic mouse studies. Second IIR Ltd Sponsored Symposium: "Successfully Managing The TSE Crisis", London, June 1998
- Telling, Glenn C . Transmissible spongiform encephalopathies: Prions. Institute of Animal Technology, Institute of Psychiatry, Kings College London, May 1998
- Telling, Glenn C. Transgenic mice and prion diseases: Sensitive bioassays and insights into mechanisms of prion propagation. "Successfully Managing The TSE Crisis", IIR Ltd. Symposium, London, March 1998
- Telling, Glenn C. Prion strains and species barriers: studies with transgenic mice. BBSRC Biology of Spongiform Encephalopathies Workshop, University of Warwick, March 1998
- Bosque, P., G. Telling, J. Cayetano, S. DeArmond and S. Prusiner. Evidence for prion replication in skeletal muscle. Ann. Neurol. 42: 986, 1997
- Prusiner, S. B., Kaneko, K., Vey, M., Telling, G ., Scott, M., Gabizon, R., Taraboulos, A., DeArmond, S. J., Cohen, F. E.: Molecular biology of prion propagation. International Seminar on Nuclear War and Planetary Emergencies, 21st Session (Zichichi, A., Ed.), pp. 49-50, 1997
- Meiner, Z., A. Yanai, G. Telling , M. Chalimi, A. Tarabolous, S. B. Prusiner and R. Gabizon: Prion protein with the E200K mutation exhibits properties similar to the cellular isoform. Neurology [Suppl.], 48: A295, 1997
- Prusiner, S. B., K. Kaneko, M. Vey, G. Telling, M. Scott, R. Gabizon, A. Tarabolous, S. J. DeArmond and F. E. Cohen: Molecular biology of prion propagation. Abstracts of papers presented at the NATO Advanced Research Workshop: Prions and Brain Diseases in Animals and Humans, Erice, Italy, 19-22, p. 22, 1996
- Gabizon, Ruth, Glenn Telling , Zeev Meiner, Michele Halimi, Irit Kahana and Stanley B. Prusiner. Altered properties of prion proteins in Creutzfeldt-Jakob disease patients heterozygous for the E200K mutation. 3rd International Symposium on Transmissible Subacute Spongiform Encephalopathies: Prion Diseases, Paris, France, 18-20 March 1996
- Prusiner, Stanley B., Martin Vey and Glenn C. Telling: Prion formation and Chaperones. 10th International Congress of Virology, Jerusalem, Israel, 1996
- Telling, Glenn C ., Patrick Tremblay, Marilyn Torchia, Stephen J. DeArmond, Fred E. Cohen and Stanley B. Prusiner: N-terminally tagged prion protein supports prion propagation in transgenic mice. Mol. Biol.Cell, 7 [Suppl.]: 651a, 1996
- Prusiner, S. B., K. Kaneko, M. Vey, G. Telling , M. Scott, S. J. DeArmond and F. E. Cohen: Prion propagation and formation of the scrapie prion protein isoform. Abstracts of papers presented at the LXI Cold Spring Harbor Symposium on Quantitative Biology: Function and Dysfunction in the Nervous System, p. 3, 1996
- Heye, N., G. C. Telling and S. B. Prusiner: Prion propagation in transgenic mice expressing human and chimeric human-mouse PrP transgenes. German Neurology Congress, Göttingen, Germany, September 25-28, 1996
- Bosque, P., G. Telling , D. Westaway, J. Cayetano, S. DeArmond and S. Prusiner. Prion protein over-expression exclusively in skeletal muscle causes spontaneous myopathy. Neurology [Suppl.], 46: 250, 1996
- Telling, Glenn . C., James A. Mastrianni, Stephen J. DeArmond and Stanley B. Prusiner. Exploring the mechanisms of prion propagation using mice expressing human and chimeric mouse/human prion protein transgenes. Neurology [Suppl.] , 46 : 488, 1996
- Prusiner, S. B., K. -M. Pan, M. A. Baldwin, G. C. Telling and M. Scott: Transgenetic investigations of prion diseases. International Symposium on Prion Diseases, Göttingen, Germany, October 26-27, 1995
- Prusiner, S. B ., K. -M. Pan, M. A. Baldwin, G. C. Telling and M. Scott: The prion diseases. AIDS Res.Hum. Retroviruses [Suppl. 1], 11: S71, 1995
- Prusiner, S. B., G. Telling , D. Groth, M. Scott and S. J. DeArmond. Transgenetics of prion diseases. Front. Endocrinol ., 16: 237, 1995
- Telling, G . and S. B. Prusiner. Transgenic mouse models of human prion diseases. 6th International Workshop on Bovine Spongiform Encephalopathy, Williamsburgh VA, 1995
- Bosque, P., G. Telling , D. Hanahan and S. B. Prusiner. Ectopic expression of the prion protein directed by the insulin gene promoter to the pancreas of transgenic mice. Neurology [Suppl.], 45: 308, 1995
- Telling, G. C ., D. Foster, S.-L. Yang, S. J. DeArmond and S. B. Prusiner. Transgenic mice expressing human and chimeric human-mouse prion proteins carrying the codon 102 mutation of GSS. Neurology [Suppl.], 45: 308, 1995
- Prusiner, S. B., G. Telling , D. Groth, M. Scott and S. J. DeArmond. Transgenetics of prion diseases. International Symposium on: "Where genotype does not match phenotype", Volterra, Italy, 1994
- Telling, G. C., M. Scott, H. Schätzl, D. Foster, S.-L. Yang, M. Torchia, F. E. Cohen, S. J. DeArmond and S. B. Prusiner. Prion transmission from humans to transgenic mice expressing chimeric human-mouse prion protein (PrP) provides evidence or a species-specific factor in prion propagation. Mol. Biol. Cell [Suppl.], 5: 473a, 1994
- Carlson, G.A., C. Ebeling, S-L. Yang, G. Telling , M. Torchia, D. Groth, D. Westaway, S. J. DeArmond and S. B. Prusiner. The prion protein gene, a novel genetic locus and prion-specified information control regional patterns of PrPSc accumulation and neuropathology in mice. Neurobiology of Aging [Suppl. 1] , 15: 157, 1994
- Telling, G. C . and S. B. Prusiner. Altered patterns of expression of mutant forms of human PrP in neuroblastoma cells. Ninth International Congress of Virology, Glasgow UK, 1993
- Telling, G., C. Liu and J. Williams. Constructing chimeric E1A genes and using them to locate an oncogenic determinant of type 12 adenovirus. Imperial Cancer Research Fund DNA Tumour Virus Symposium, Cambridge UK, 1993
- Telling, G. C ., S. Periera and J. Williams. A dubious oncogene; evidence that the product of the type 5 adenovirus E1B 19K gene is not required for transformation of rodent cells. Imperial Cancer Research Fund DNA Tumour Virus Symposium, Cambridge UK, 1999
- Hayes, B. W., G. C. Telling , J. F. Williams and S. J. Flint. An adenovirus 5 late non-structural protein regulates the efficiency of viral late mRNA translation. Cold Spring Harbor Laboratory Translational Control Symposium, Cold Spring Harbor Laboratory NY, 1990
United States and International Patents
Papers submitted or in preparation
Papers published or in press
Book Chapters
Other publications
Abstract
Books
Prions and Prion Diseases: Current Perspectives. Glenn C. Telling (Ed.) Horizon Scientific Press, Wymondham UK, 2004
D. Invited symposia and workshops
Feb 2008 | Second annual PrPCANADA meeting: "Making Tracks" Toronto, Canada, |
Sept 2007 | NeuroPrion2007 - Chronic Wasting Disease Workshop, Edinburgh UK"Transgenic mouse models of chronic wasting disease" |
May 2007 | 107th General Meeting of the American Society for Microbiology, Toronto, Canada"Transgenic Mouse Models of Chronic Wasting Disease" |
July 2007 | 144th AVMA Annual Convention, Washington DC"Transgenic Mouse Models for Chronic Wasting Disease research " |
Jan 2007 | Emerging and Re-emerging viral infections in the human nervous system, Winter Conference on Brain Research, Snowmass, CO "Emerging and Re-emerging viral infections of the human nervous system: What we know from the past and what we need to know for the future" |
Aug 2006 | 10th International Symposium for Zoonosis Control - Protection of Society from infectious Threat , Sapporo, Japan "Deciphering mechanisms of prion transmission using transgenic mice" |
Aug 2006 | Ninty-sixth Association of American Feed Control Official's (AAFCO) annual meeting, TSE Issues committee meeting, Oklahoma City, OK "Transgenic mouse models of prion diseases" |
April 2006 | Mini-Symposium on Prion Diseases, National Animal Disease Center, Ames, IA "Transgenic mouse models of chronic wasting disease and other prion disorders" |
Feb 2006 | Alberta Prion Research Symposium, Alberta Prion Research Institute, Calgary Canada" Transgenic mouse models of chronic wasting disease" |
Nov 2005 | IBC's Second Annual Transmissible Spongiform Encephalopathies (TSEs) meeting - Science and Strategies to Detect and Control Infectivity in Biopharmaceuticals and Blood Products, Reston, VA " Transgenic mouse models of chronic wasting disease" |
Nov 2005 | Prion Biology: Puzzles and Paradoxes, The Banbury Center, Cold Spring Harbor, New York "Transgenic studies of CWD and mechanisms controlling prion transmission barriers" |
Oct 2005 | International Symposium on Advanced Virology, Beijing, China, "Transgenic mouse models of human and animal prion diseases" (Keynote Address) |
Oct 2005 | International Conference: "Prion 2005 - Between fundamentals and society's needs" Düsseldorf, Germany, "Transgenetic studies of chronic wasting disease" |
Oct 2005 | National Institute of Toxicological Research International Symposium, Seoul , Korea , " Transgenic mouse models of chronic wasting disease " |
Oct 2005 | Mad Cow and related TSE diseases: Science, Risks and Public Policy, University of Connecticut, " Recent breakthroughs in chronic wasting disease research" |
Sept 2005 | World Health Organization (WHO) Consultation on Tissue Infectivity Distribution in Transmissible Spongiform Encephalopathies, WHO Headquarters, Geneva, "Progress in detection and quantification of prion infectivity by bioassay in transgenic mice " |
July 2005 | Second International Chronic Wasting Disease Symposium, Madison, Wisconsin, "Studying CWD biology with transgenic mice" (Organizer and Chair) |
April 2005 | Second International Symposium "The New Prion Biology: Basic Science, Diagnosis and Therapy", Venice, Italy, "Transgenic models of prion replication" |
Oct 2004 | CWD/TSE Symposium, North Dakota State Board of Animal Health, Bismarck, ND, "Recent breakthroughs in CWD research" |
Oct 2004 | Animal Prion Diseases in the Americas, Ames, IA, " Transgenetic studies of chronic wasting disease" |
Oct 2004 | Forty-fourth Interscience Conference on Antimicrobial Agents and Chemotherapy Prion Disease Symposium, Washington DC, "Transgenic models of prion replication" |
March 2004 | Center for Food and Nutrition Policy Forum: Transmissible Spongiform Encephalopathies in Animal and Human Health: The Science and the Policy, Virginia Tech, "Transgenic approaches for studying chronic wasting disease" |
Oct 2003 | International Prion Conference: From Basic Research to Intervention Concepts, München - Germany, " Prion propagation is a calpain-dependent process" |
May 2003 | Food Research Institute Annual Meeting, Madison WI, "An update on chronic wasting disease and other Prion diseases" |
Aug 2002 | Chronic wasting disease symposium, Denver, CO, "Prion Diseases - Overview of General Concepts" |
Aug 2002 | Chronic wasting disease symposium, Denver, CO, "Production and Preliminary Characterization of Transgenic Mice for studying chronic wasting disease" |
Feb 2002 | NIH-sponsored TSE workshop, Bethesda, MD |
Oct 2001 | Interdisciplinary Conference on State Law and Public Health, Lexington, KY, "Policy Issues in Bovine Spongiform Encephalopathy and other food borne diseases" |
June 2001 | Symposium on the neuropathology of neurodegenerative diseases, Indiana University, "New transgenic and in vitro approaches for studying prion diseases " |
May 2000 | First Conference of the Creutzfeldt-Jakob disease Foundation, Inc., Miami, Florida, " Studying human prion diseases in transgenic mice" |
April 2000 | Biotechnology and Biological Sciences Research Council (BBSRC) Biology of Spongiform Encephalopathies (BSEP) Workshop , Keele, UK, "Perspectives on the use of transgenic mice" (Organizer and Chair) |
Sept 1999 | International Symposium on the characterization and diagnosis of prion diseases in animals and man, Tubingen, Germany, " Transgenic studies of prion transmission barriers"(Chair) |
Aug 1999 | Thirteenth International Conference on Lymphoid Tissues in Immune Reactions, Geneva, Switzerland, "Prion strains and species barriers: Investigating Creutzfeldt Jakob disease, BSE and other prion diseases in transgenic mice" |
July 1999 | Eighteenth summer course at Universidad del Pais Vasco/Euskal Herriko Unibersitatea, San Sebastian, Spain, "Bovine Spongiform Encephalopathy in the United Kingdom and the relationship with the new variant of Creutzfeldt-Jakob disease in humans: An update" |
June 1999 | National Academy of Sciences (NAS) and the German American Academic Council's 5th Annual German-American Frontiers of Science Symposium: Potsdam, Germany, (Organizer) |
Nov 1998 | Critical data and scientific uncertainties: The statistics of transmissible spongiform encephalopathies (TSE's), Isaac Newton Institute for Mathematical Sciences, University of Cambridge, |
June 1998 | National Academy of Sciences (NAS) and the German American Academic Council's 4th Annual German-American Frontiers of Science Symposium, Irvine, California, (Organizer) |
Sept 1998 | Institute of Psychiatry Short Course in Old Age Psychiatry, Institute of Psychiatry, Kings College, London, "Transmissible Dementias" |
July 1998 | Sixth International Conference on Alzheimer's Disease and Related Disorders, Amsterdam, The Netherlands, "Transgenic Mouse Models of Prion Diseases" |
June 1998 | ‘Successfully Managing the TSE Crisis', Second IIR Ltd. Sponsored Symposium, London, "Insights into the mechanisms of prion propagation from transgenic mouse studies" |
March 1998 | Biomed 2 - Third Collaborators' Meeting, St Moritz, Switzerland, "Strains, species barriers and mechanisms of prion propagation: Studies with transgenic mice" |
March 1998 | Biotechnology and Biological Sciences Research Council (BBSRC) Biology of Spongiform Encephalopathies (BSEP) Workshop, University of Warwick, "Prion strains and species barriers: Studies with transgenic mice" |
March 1998 | ‘Successfully Managing the TSE Crisis', IIR Ltd. Sponsored Symposium, London, "Insights into the mechanisms of prion propagation from Transgenic mouse studies" |
Feb 1998 | Royal College of Physicians, Advanced Medicine Conference, London, "BSE" |
Dec 1997 | Microsymposium on Prions and Prion Diseases, Institut Fur Molekularbiologie Abteilung I, Universitat Zurich, Switzerland, "Prion strains and species barriers: an update on transgenic mouse work" |
Nov 1997 | National Academy of Sciences' (NAS) 9 th Annual Frontiers of Science Symposium, Irvine CA, "Transgenic Models of Prion Diseases" |
Sept 1997 | Joint Congress of the German Societies of Clinical Chemistry and Laboratory Medicine on Molecular Diagnostics, Munster Germany, "Diagnostic markers of prion disease" |
Sept 1997 | The Congress of the Institute of Biomedical Science, Biomedical Science Congress, International Convention Centre, Birmingham UK, "BSE and the public health" |
June 1997 | National Academy of Sciences (NAS), Max-Planck-Society and the German American Academic Council's 3rd Annual German-American Frontiers of Science Symposium, Munich, Germany, (Organizer) |
June 1997 | Second Annual Centeon/ UCSF Meeting, Monterey CA, "New Models and Validation of the Transgenic Human Prion Assay" |
Dec 1996 | International Symposium on Spongiform Encephalopathies: Generating Rational Policy in the Face of Public Fears. The Ceres Forum of the Center for Food and Nutrition Policy at Georgetown University and the American Association of the Veterinary Medical Colleges, Georgetown University, Washington DC, "Prion Research" |
Nov 1996 | National Academy of Sciences' (NAS) 8th Annual Frontiers of Science Symposium, Irvine CA, |
June 1996 | National Academy of Sciences (NAS), German American Academic Council 2nd Annual Symposium on German-American Frontiers of Science, Woods Hole MA, "Prion Propagation and Protein X using Transgenic Mice" |
May 1996 | Ninety-sixth General Meeting of the American Society for Microbiology. Prion Proteins Session: "A Novel Mechanism for Inheritance", New Orleans LA, "Prion Biology and Diseases of Mammals" |
April 1996 | First Annual Centeon/UCSF Meeting, Napa Valley CA, "Abbreviated Assays for Human and Domestic Animal Prions" |
Jan 1996 | Food and Drug Administration (FDA) and the National Heart, Lung and Blood Institute (NHLBI), Bethesda MD, "Optimal methods to detect prion infectivity in human blood: Transgenic mice expressing human and chimeric human-mouse prion proteins" |
Nov 1995 | Symposium on the Molecular Biology of Prions and Pathology of Prion Diseases, The Banbury Center, Cold Spring Harbor Laboratory, NY, "Prion propagation and protein X in transgenic mice" |
Feb 1995 | Sixth International Workshop on Bovine Spongiform Encephalopathy, Williamsburg VA, "Transgenic ` mouse models of human prion diseases" |
Oct 1994 | Serono Symposia International Symposium on: Where genotype does not match phenotype, Volterra, Italy, "Transgenetics of prion diseases" |
Aug 1993 | Ninth International Congress of Virology, Glasgow, UK, "Altered patterns of expression of mutant forms of human PrP in neuroblastoma cells" |
1991 | Imperial Cancer Research Fund DNA Tumor Virus Symposium, Cambridge UK, "A dubious oncogene; evidence that the product of the type 5 adenovirus E1B 19K gene is not required for transformation of rodent cells" |
E. Invited lectures
Oct 2007 | Division of Infectious Diseases, University of Kentucky, Lexington, "Prion Diseases" |
July 2007 | Institut fur Virologie Technischen Universitat Munchen, Munich Germany, "Transgenic mouse models of prion diseases" |
June 2007 | Department of Medical Microbiology and Immunology, Creighton University, "Transgenic mouse models of prion diseases" |
Sept 2006 | Veterinary Laboratories Agency, United Kingdom, "Modeling prion transmission barriers in transgenic mice" |
July 2006 | Nathan Shock Center on Aging Seminar Series, University of Rochester School of Medicine and Dentistry, New York, "Modeling prion transmission barriers in transgenic mice" |
April 2006 | Department of Biological Sciences, University of Alberta, Edmonton, Canada, "Modeling prion transmission barriers in transgenic mice" |
April 2006 | Center for Alzheimer's Disease Research, University of Texas Medical Branch, Galveston, TX, "Modeling prion transmission barriers in transgenic mice" |
Feb 2006 | Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, "Transgenic mouse models of chronic wasting disease and other prion disorders" |
Nov 2005 | Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, "Transgenic studies of chronic wasting disease and other prion disorders" |
Oct 2005 | School of Veterinary Medicine, Seoul National University, Korea,"Transgenic approaches for studying prion diseases and mechanisms of prion propagation" |
Oct 2005 | ILSong Institute of Life Science and College of Medicine, Hallym University, Korea, "Transgenic studies of chronic wasting disease" |
Sept 2005 | Department of Microbiology, Miami University, Oxford, OH, "Transgenic approaches for studying prion diseases and mechanisms of prion propagation" |
Sept 2005 | Sanders Brown Center on Aging, University of Kentucky, "Recent breakthroughs in prion disease research" |
June 2004 | Department of Neurology Grand Rounds, University of Kentucky, "Recent advances in prion disease research" |
May 2005 | Institute of Biological Sciences and Technology, Beijing Jiaotong University, Beijing, China, "More mechanistic studies of prion propagation" |
May 2005 | Chinese Center for Disease Control and Prevention, Institute of Virology, Beijing, China, "Mechanistic studies of prion propagation" |
May 2005 | National Quarantine Institute, Key Laboratory of the Ministry of Agriculture, Tsingdao, China, "Mechanistic studies of prion propagation" |
May 2005 | Department of Microbiology, Shandong University, China, "Mechanistic studies of prion propagation" |
May 2005 | Medical School of Shandong University, China, "Transgenic studies of prion diseases and other neurodegenerative disorders of protein folding" |
Feb 2005 | Department of Veterinary Molecular Biology, Montana State University, Bozeman, MT, "Transgenic approaches for studying chronic wasting disease, a prion disease of cervids" |
Sept 2004 | Division of Infectious Diseases, University of Kentucky, Lexington, "Prions and the Prion Diseases" |
April 2004 | -------------------------------------------------------------------------- |
Mar 2004 | Nathan Shock Center on Aging Seminar Series, University of Rochester School of Medicine and Dentistry, New York, "Transgenetic models of prion replication" |
Jan 2004 | Department of Molecular and Cellular Biochemistry, Ohio State University, "Transgenic and in vitro approaches for studying mechanisms of prion propagation" |
Jan 2004 | Department of Neurology Grand Rounds, University of Kentucky, "Transgenic and cell culture approaches for studying the mechanism of prion propagation" |
April 2003 | Department of Biochemistry and Medicine, Dartmouth Medical School, NH, "Transgenic and cell culture models of human and animal prion diseases" |
June 2002 | Department of Pathology and Laboratory Sciences, University of Ottawa, Canada, "Transgenic and cell culture models of human and animal prion diseases" |
April 2002 | Division of Infectious Diseases, University of Kentucky, Lexington, "Prions" |
Nov 2001 | --------------------------------- --------------------------------- |
Dec 2001 | Nathan Shock Center on Aging Seminar Series, University of Rochester School of Medicine and Dentistry, New York, "Transgenic and in vitro approaches for studying prion diseases " |
Jan 2001 | Department of Pathology, University of Kentucky, Lexington, "Prions" |
Nov 2000 | Department of Biological Sciences, University of Kentucky, Lexington, " Transgenic approaches for studying prion diseases" |
Oct 2000 | Sanders-Brown Center on Aging Seminar Series, University of Kentucky, " New transgenic and in vitro approaches for studying prion diseases " |
Sept 2000 | Department of Molecular and Cell Biology, University of Texas, Dallas, "Deciphering prion diseases using transgenic mice" |
Feb 2000 | Department of Neurology, University of Kentucky, Lexington, "Transgenic models of CJD" |
Feb 2000 | Department of Pathology, Case Western Reserve University, "Transgenic approaches for studying prion diseases" |
April 1999 | Division of Medical and Molecular Genetics, King's College at Guy's Hospital, London, "Deciphering prion diseases using transgenic mice" |
April 1999 | Sanders-Brown Center on Aging, University of Kentucky, Lexington, "Deciphering prion diseases using transgenic mice" |
Oct 1998 | Department of Molecular, Cellular and Developmental Biology, University of Colorado, "Deciphering prion diseases with transgenic mice" |
Oct 1998 | Department of Pathology, Colorado State University, "Deciphering prion diseases with transgenic mice" |
May 1998 | Institute of Animal Technology, Institute of Psychiatry, Kings College London, "Prion hypothesis" |
April 1998 | Institute for Animal Health, Neuropathogenesis Unit, Edinburgh, "Transgenetic investigations of TSE's" |
Jan 1998 | Institute of Psychiatry, Department of Neuroscience, London, "Transgenic Models of Prion Diseases" |
Dec 1997 | Division of Biomedical Sciences, Imperial College of Medicine at St. Mary's, "Transgenetic investigations of prion diseases" |
Sept 1997 | University of Birmingham, "Transgenetic investigations of prion diseases" |
June 1997 | Max von Pettenkofer Institut, University of Munich, Munich, Germany, "Investigating Prion Diseases with Transgenic Mice" |
May 1997 | University Pacific School of Dentistry, San Francisco CA, "Prion Proteins and Mad Cow Disease: Should a Dentist be Concerned?" |
May 1997 | University of California, Berkeley, "Prions" |
Jan 1997 | Neurogenetics Unit, Imperial College of Medicine at St Mary's, "Transgenic Mice and the Prion Diseases: Recent Breakthroughs and Future Directions" |
Nov 1995 | Departments of Biological Sciences, Carnegie Mellon University and University of Pittsburgh, Pittsburgh PA, "Prion transmission from humans to transgenic mice: Insights into the mechanisms of prion propagation" |
June 1995 | Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill NC, "Mechanisms of Prion Propagation from Transgenic mice expressing chimeric human-mouse prion proteins" |
March 1995 | ------------------------------------- ----------------------------- ---------------------------- ------------------------- ----------------- --------------------------- |
March 1995 | Department of Biochemistry and Biophysics, University of California, San Francisco CA, "Transgenic mice for studying human prion diseases" |
June 1994 | Medical Research Council (MRC), Laboratory of Molecular Biology, Cambridge, UK, "Transgenic mice for studying human prion diseases" |
Dec 1990 | The George Williams Hooper Foundation, University of California, San Francisco CA, "Genetic analysis of the functions of the adenovirus E1 proteins in oncogenic transformation and lytic infection" |