Sensing and Responding to DNA Damage

 


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Air date: Wednesday, March 05, 2003, 3:00:00 PM
Category: DNA Repair
Description: The NIH Director's Wednesday Afternoon Lecture Series

Cancer occurs by the accumulation of mutations in growth-controlling genes. Conditions under which increased frequencies of mutations occur often lead to cancer, and there are several examples of human diseases that cause higher mutation rates and result in a predisposition to cancer. Enhanced mutation frequencies can result from environmental factors, such as increased exposure to DNA-damaging agents, or genetic factors that decrease the efficiency of normal DNA repair processes.

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Stephen Elledge
Author: Stephen J. Elledge, Ph.D., Baylor College of Medicine
Runtime: 01:02:38
Rights: This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
CIT File ID: 10562
CIT Live ID: 1885
Permanent link: http://videocast.nih.gov/launch.asp?10562