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Centers for Disease Control and Prevention

Vaccines & Immunizations


Manual for the Surveillance of Vaccine-Preventable Diseases
4th Edition, 2008

The Manual for the Surveillance of Vaccine-Preventable Diseases provides current guidelines for those directly involved in surveillance of vaccine-preventable diseases, especially personnel at the local health departments. For each of the vaccine-preventable diseases, this manual includes a chapter describing the importance of rapid case identification; the importance of surveillance; disease reduction goals; case definitions (including clinical description and case classifications); epidemiologically important data to be collected during case investigation; activities for enhancing surveillance; activities for case investigation; and activities for outbreak control. Other chapters include information on surveillance indicators; surveillance data analyses; reporting adverse events following vaccination; and enhancing surveillance. In addition, the manual includes a section reserved for insertion of state-specific guidance for VPD surveillance and extensive appendices.

Manual for the Surveillance of Vaccine-Preventable Diseases

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This manual is available only through this website and is no longer offered in a printed version. Offering the manual online keeps the manual as current as possible. As changes occur, the chapters will be replaced with updated versions.

Compressed Section Bundles

These compressed bundles, saved in .zip format, contain all the files for each section (outlined below) and may have a file size prohibitive to those with slow Internet connections.

  • All Front Matter Adobe Acrobat print-friendly PDF file (PDF 269 KB)
  • All Chapters Adobe Acrobat print-friendly PDF file (PDF 3.43 MB)
    WARNING:file size is large and will take a while to download.
  • All Appendices Adobe Acrobat print-friendly PDF file (?? MB)  Coming Soon

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Individual Downloads

The individual files of the 2008 Manual for the Surveillance of Vaccine-Preventable Diseases are listed below.

List of Front Matter

  • Front portion of manual Adobe Acrobat print-friendly PDF file (PDF 269 KB)
    Cover, spine, title pages (titles and acknowledgements), acronyms, definition of terms, table of contents, introduction, etc.

List of Chapters

The first link goes directly to the chapter's web page. However, most will want to print these chapters using the second link (PDF) which opens in Adobe Reader.

List of Appendices

Below is a list of appendices for the Manual of Surveillance of Vaccine-Preventable Diseases. As they are completed, a link will be provided to the appendix. Please check back often. If you wish to be notified by email when this web page is updated and hence when appendices are added, please use the Get Email Updates link located at the top of this page.

  • Appendix 1: Collection of Specimens for Isolation of C. diphtheriae (Ch. 1)

  • Appendix 2: Guidelines for managing a suspected case of diphtheria and for managing contacts (Ch. 1)

  • Appendix 3: CDC Diphtheria Worksheet (Ch. 1)

  • Appendix 4: Haemophilus influenzae Worksheet – NETSS Haemophilus influenzae Worksheet – NEDSS (Ch. 2)

  • Appendix 5: Expanded Haemophilus influenzae type B Surveillance Worksheet (Ch. 2)

  • Appendix 6: Hepatitis Data Collection Worksheet (Ch. 3 and 4)

  • Appendix 7: Measles Virus Isolation (Ch. 7)

  • Appendix 8: Measles Surveillance Worksheet (Ch. 7)

  • Appendix 9: Meningococcal Disease Surveillance Worksheet – NETSS Meningococcal Disease Surveillance Worksheet - NEDSS (Ch. 8)

  • Appendix 10: Mumps Surveillance Worksheet (Ch. 9)

  • Appendix 11: Pertussis Surveillance Worksheet – NETSS Pertussis Surveillance Worksheet - NEDSS (Ch. 10)

  • Appendix 12: Pertussis Death Worksheet (Ch. 10)

  • Appendix 13: Streptococcus pneumoniae Surveillance Worksheet (Ch. 11)

  • Appendix 14: Suspected Polio Case worksheet Investigation of suspected case of poliomyelitis (Ch. 12)

  • Appendix 15: Collection of Specimens for Typing of Rubella Virus (Ch. 14)

  • Appendix 16: Rubella Surveillance Worksheet (Ch. 14)

  • Appendix 17: Congenital Rubella Syndrome Case Worksheet (Ch. 15)

  • Appendix 18: Tetanus Surveillance Worksheet (Ch. 16)

  • Appendix 19: Varicella Death Investigation Worksheet (Ch. 17)

  • Appendix 20: Varicella Outbreak Reporting Worksheet Varicella Surveillance Worksheet (Ch. 17)

  • Appendix 21: Updated Guidelines for Evaluating Public Health Surveillance Systems (Ch. 18)

  • Appendix 22: VAERS form (Ch. 21)

  • Appendix 23: CDC Specimen Submission Form http://www.cdc.gov/ncidod/dvbid/misc/5034.pdf (Ch. 22)

  • Appendix 24: Interstate Shipment of Etiologic Agents (Ch. 22)

  • Appendix 24: Packaging and Shipping of Biomedical Material (Ch. 22)

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This page last modified on September 4, 2008
Content last reviewed on August 26, 2008
Content Source: National Center for Immunization and Respiratory Diseases

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