Rach, J.J., S. M. Schleis, T. M. Schreier, and M.P. Gaikowski.  2002.  Efficacy of 
hydrogen peroxide to control mortality associated with external columnaris on channel 
catfish fingerlings (Ictalurus punctatus). Submitted to the U.S. Food and Drug 
Administration Center for Veterinary Medicine, November 22, 2002.   136 pp.

A clinical field trial was conducted at the Rathbun State Fish Hatchery (Moravia, Iowa) 
to evaluate the efficacy of hydrogen peroxide to control mortality associated with 
external columnaris on channel catfish fingerlings.  The treatment regimens administered 
(static) were 0, 50, 75 or 100 mg/L hydrogen peroxide for 60 min every-other-day for a 
total of three treatments.  Each treatment regimen was tested in triplicate and each 
replicate contained 26 fish at test initiation.  At the end of the trial, mean percent fish 
survival were 19.2% (control), 52.6% (50 mg/L), 71.8% (75 mg/l), and 59% (100 mg/L).  
Statistical analysis indicated that mean percent survival was significantly greater in fish 
treated with 50, 75 and 100 mg/L hydrogen peroxide compared to control fish that 
received no chemical treatment.