Fellowships, Grants, and Awards
For more information on job openings in the environmental health sciences, see EHP's Career Opportunities page. For more information on employment and training at the NIEHS, see http://www.niehs.nih.gov/external/emptrain.htm. Complete information on NIH funding opportunities and notices is available at http://grants.nih.gov/grants/guide/index.html.
For advertisers only: If you would like to publish a Fellowship, Grant, or Award announcement in EHP, please e-mail Erin Dooley at dooley@niehs.nih.gov.
Research to Advance Vaccine Safety (R01)
This Funding Opportunity Announcement, entitled Research to Advance Vaccine Safety, is issued by the National Institutes of Health and encourages Research Project Grant (R01) applications from institutions/organizations that propose to support research that will contribute to the overall understanding of vaccine safety. This R01 research opportunity invites studies that address scientific areas potentially relevant to vaccine safety such as 1) physiological and immunological responses to vaccines and vaccine components, 2) how genetic variations affect immune/physiological responses that may impact vaccine safety, 3) identification of risk factors and biological markers that may be used to assess whether there is a relationship between certain diseases or disorders and licensed vaccines, or 4) the application of genomic/molecular technologies to improve knowledge of vaccine safety. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-256.html
Research to Advance Vaccine Safety (R21)
This Funding Opportunity Announcement (FOA), entitled Research to Advance Vaccine Safety, is issued by the National Institutes of Health and encourages Exploratory/Developmental (R21) grant applications from institutions/organizations that propose to support research that will contribute to the overall understanding of vaccine safety. This R21 research opportunity invites studies that address scientific areas potentially relevant to vaccine safety such as 1) physiological and immunological responses to vaccines and vaccine components, 2) how genetic variations affect immune/physiological responses that may impact vaccine safety, 3) identification of risk factors and biological markers that may be used to assess whether there is a relationship between certain diseases or disorders and licensed vaccines, or 4) the application of genomic/molecular technologies to improve knowledge of vaccine safety. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-257.html
Novel Approaches for Assessing Exposure for School-Aged Children in Longitudinal Studies
A key issue faced by researchers conducting large population studies of children's environmental health is the challenge of assessing exposure. Traditional exposure assessment methods depend on questionnaires and multiple environmental samples, but these tend to be costly and create a burden of time and effort for both study participants and researchers. There is also little information about how exposures change over time as children age and begin to spend more time outside the home in places such as child care locations, schools and playgrounds. Research is needed to assess whether there are differences in nonresidential environments that may lead to changes in exposure estimates and/or classifications for children. The U.S. Environmental Protection Agency (EPA), as part of its Science to Achieve Results (STAR) program, is soliciting applications proposing research to develop and evaluate novel, innovative approaches for classifying exposure for children 2 to <11 years of age to toxic chemicals in their environment for use in large-scale longitudinal exposure assessment and epidemiological studies. These approaches could include the use of targeted direct and indirect exposure related measurements, biological markers (biomarkers), questionnaires and surveys, community and regional-level measurements, mathematical models and classification schemes and informatic approaches such as principal component analysis. The methods and/or tools developed and evaluated could include an "exposure index" that could be used to characterize and classify individual exposure status (for example, high, medium, or low) of children for exposure to chemical agents and other environmental factors across life stages. The complete version of this announcement is available at http://es.epa.gov/ncer/rfa/2008/2008_star_novelapproaches.html
Integration of Mouse Models into Human Cancer Research (U01)
This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), extends the NCI-Mouse Models of Human Cancers Consortium (NCI-MMHCC) for a third project period. The previous periods resulted in generation, validation, and utilization of many novel mouse cancer models. Having successfully attained the original specific program goals, the NCI-MMHCC is poised to enter the next stage that stresses the use of biologically relevant mouse models as effective tools for human research. The overall objective of the NCI-MMHCC is integration of mouse models into basic, translational, epidemiological, and clinical cancer research. Goal 1 of the NCI-MMHCC is to support individual research projects that promote innovation in use of mouse models to address crucial questions in human cancer research. All applicants who respond to this FOA must submit applications for regular research project awards that address Goal 1. To facilitate the overall research and integration goals, the NCI-MMHCC will also support up to four Science Leadership components to coordinate activities in defined scientific areas ("research clusters") under Goal 2 "Science Leadership and Integration". Goal 2 includes (a) coordinating intra-NCI-MMHCC projects in specific research clusters; (b) enhancing collaborations throughout the NCI-MMHCC and with NCI networks and consortia; and (c) expanding the NCI cancer models bioinformatics infrastructure and integrating it with human cancer bioinformatics. The Science Leadership components must be based on the science of appropriate research projects. Therefore, only applicants who submit research project applications may also submit separate applications for Science Leadership components to serve Goal 2. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-08-018.html
Chronic Fatigue Syndrome: Pathophysiology and Treatment (R01)
This Funding Opportunity Announcement issued by the Office of Research on Women's Health and co-sponsoring Institutes and Centers of the National Institutes of Health (NIH) encourages investigator(s)-initiated applications that propose to examine the etiology, diagnosis, pathophysiology, and treatment of chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME/CFS) in diverse groups and across the lifespan. Innovative applications that address gaps in the understanding of the environmental and biological risk factors, the determinants of heterogeneity among patient populations, and the common mechanisms influencing the multiple body systems that are affected in CFS are encouraged. The NIH is particularly interested in funding interdisciplinary research that will enhance our knowledge of the disease process and provide evidence based solutions to improve the diagnosis, treatment, and quality of life of all persons with CFS. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-246.html
Chronic Fatigue Syndrome: Pathophysiology and Treatment (R21)
This Funding Opportunity Announcement issued by the Office of Research on Women's Health and co-sponsoring Institutes and Centers of the National Institutes of Health (NIH) encourages investigator(s)-initiated applications that propose to examine the etiology, diagnosis, pathophysiology, and treatment of chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis (ME/CFS) in diverse groups and across the lifespan. Innovative applications that address gaps in the understanding of the environmental and biological risk factors, the determinants of heterogeneity among patient populations, and the common mechanisms influencing the multiple body systems that are affected in CFS are encouraged. The NIH is particularly interested in funding interdisciplinary research that will enhance our knowledge of the disease process and provide evidence based solutions to improve the diagnosis, treatment, and quality of life of all persons with CFS. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-247.html
Metals in Medicine (R01)
The objective of this Funding Opportunity Announcement, issued by the National Institute of General Medical Sciences, National Cancer Institute, National Institute of Environmental Health Sciences, and the Office of Dietary Supplements, National Institutes of Health is to encourage research that bridges the areas of inorganic chemistry and medicine. The mechanisms by which organisms control transition metal ions and the roles of these metals in cellular regulation and signaling in health and disease are of principal interest. The interactions of synthetic inorganic complexes with living systems and their components are an additional area of interest. These areas are linked by the need to involve researchers having a deep understanding of inorganic chemistry in medically relevant research. Much of the work is expected to involve collaborations including chemists, biologists, and medical researchers. The results will be relevant to understanding the mechanisms of metal handling by biological systems and the basic cellular roles underlying the nutritional requirement for essential metals. It is expected that this research will also contribute to the identification of new targets for drug discovery, diagnostics, and future therapeutic approaches involving metal complexes, although drug development, per se, is not a focus of the program. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-251.html
Small Grants Program for Cancer Epidemiology (R03)
This funding opportunity announcement (FOA), issued by the National Cancer Institute, encourages the submission of Small Research Grant (R03) applications for research on cancer etiology and epidemiology. The overarching goal of this FOA is to provide support for pilot projects, testing of new techniques, secondary analyses of existing data, development and validation of measurement methods, linkage of genetic polymorphisms with other variables related to cancer risk, and development of innovative projects for more comprehensive research in cancer etiology and epidemiology. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-237.html
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32)
The National Institutes of Health (NIH) will award Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) to eligible institutions as the primary means of supporting predoctoral and postdoctoral research training to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the Nation's biomedical, behavioral and clinical research agenda. The primary objective of the T32 program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program supports predoctoral, postdoctoral and short term research training programs at domestic institutions of higher education with the T32 funding mechanism. Note that programs solely for short-term research training should not apply to this announcement, but rather the separate (T35) NRSA Short-Term Institutional program exclusively reserved for short-term programs (see PA-08-227). The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-226.html
Ruth L. Kirschstein National Research Service Award Short-Term Institutional Research Training Grants (T35)
The National Institutes of Health (NIH) will award Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grants (T35) to eligible institutions to develop or enhance research training opportunities for individuals interested in careers in biomedical, behavioral and clinical research. Many of the NIH Institutes and Centers (ICs) use this grant mechanism exclusively to support intensive, short-term research training experiences for students in health professional schools during the summer. In addition, the Short-Term Institutional Research Training Grant may be used to support other types of predoctoral and postdoctoral training in focused, often emerging scientific areas relevant to the mission of the funding IC. The proposed training must be in either basic, behavioral or clinical research aspects of the health-related sciences. This program is intended to encourage graduate and/or health professional students to pursue research careers by exposure to and short-term involvement in the health- related sciences. The training should be of sufficient depth to enable the trainees, upon completion of the program, to have a thorough exposure to the principles underlying the conduct of research. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-227.html
Fogarty International Research Collaboration – Basic Biomedical (FIRCA-BB) Research Award (R03)
This Funding Opportunity Announcement (FOA), the "Fogarty International Research Collaboration – Basic Biomedical (FIRCA-BB) Research Award" program, facilitates collaborative basic biomedical research between scientists supported by the National Institutes of Health (NIH) and investigators in low- to middle-income countries (LMIC). All non-AIDS-related biomedical research topics that are supported by the NIH, including basic, clinical, and applied research that does not involve behavioral or social science topics and techniques, are eligible for inclusion under the FIRCA-BB program. Special consideration will be given to proposed research that addresses significant global health problems, particularly those of high relevance to an LMIC country or region. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-222.html
Fogarty International Research Collaboration
Behavioral and Social Sciences (FIRCA-BSS) Research Award (R03)
This Funding Opportunity Announcement (FOA), the "Fogarty International Research Collaboration – Behavioral and Social Sciences (FIRCA-BSS) Research Award" facilitates collaborative behavioral and social sciences research between scientists supported by the National Institutes of Health (NIH) and investigators in low- and middle-income countries (LMIC). Special consideration will be given to proposed research that addresses significant global health problems, particularly those of high relevance to an LMIC country or region. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-223.html
Using Systems Science Methodologies to Protect and Improve Population Health (R21)
This funding opportunity announcement (FOA) is being issued by the Office of Behavioral and Social Sciences Research (OBSSR) of the National Institutes of Health (NIH) with participation from the following NIH components: FIC, NCI, NIA, NICHD, NCCAM, NHLBI, NIEHS, NIMH, NIAAA, NIDCR, NIDA, ODP, and ODS. This FOA solicits Exploratory/Developmental (R21) applications from institutions/organizations that propose to apply one or more specific system science methodologies (identified in Section I.1 – "Background", of this announcement) to public health and health care systems problems and contribute knowledge that will enhance effective decision making around the development of and prioritization of policies, interventions, and programs to improve population health, especially where resources are limited and only a limited number of programs/policies/interventions can be implemented. Applicants are encouraged to submit projects that tackle "policy resistant" health problems (i.e., ones in which the effects of planned interventions, programs or policies tend to be delayed, diluted or defeated by responses of the system to the intervention itself) using a systems science methodology. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-224.html
Adaptation for Future Air Quality Analysis and Decision Support Tools in Light of Global Change Impacts and Mitigation
The Environmental Protection Agency (EPA) Office of Research and Development, National Center for Environmental Research, in cooperation with the EPA Global Change Research Program, announces an extramural funding competition supporting research into the consequences for air quality of global change-including climate, climate variability, land-use, economic development, and technology. EPA is interested in supporting research that will further the scientific understanding of how to better adapt the air quality management system to effectively account for climate change and related mitigation impacts. In addition to regular awards, this solicitation includes the opportunity for early career projects. The complete version of this announcement is available at http://es.epa.gov/ncer/rfa/2008/2008_star_adaptation.html
Implementation Planning Grants for Educational, Behavioral, or Social Studies for Translation of Genetic Factors in Common Diseases (U34)
The National Institute of Diabetes and Digestive and Kidney Diseases on behalf of the NIH Genes, Environment and Health Initiative solicits Implementation Planning Grant (U34) applications from institutions/ organizations that propose to plan for multicenter research on a) educational and communication initiatives for health care providers and consumers regarding interpretation of and findings from genetic studies of common diseases and the results of their dissemination and b) behavioral or psychosocial aspects of clinical application of genetic findings. Areas of interest include, but are not limited to: research on patient or provider education regarding genetic findings or clinical outcomes of genetic testing; research on patient or provider perceptions of environmental or other risk factors that may have specific interactions with gene variants; and assessments of responses to use of personal genetic information in clinical care and disease prevention. The proposed research must focus on using findings from genetic studies of common diseases with complex genetic etiology in clinical settings. This FOA will support planning and preliminary or feasibility studies for investigator-initiated, multi-center clinical studies through an implementation planning (U34) grant. The U34 planning grant is designed to: (1) permit early peer review of the rationale for the proposed clinical study; (2) permit assessment of the design/protocol of the proposed study; (3) provide support for the development of a complete study protocol and associated documents including a manual of operations, (4) support the development of other essential elements required for the conduct of a clinical study, and (5) carry out key preliminary or feasibility studies. Completion of the required products of a U34 grant is a prerequisite for submission of a multi-center clinical study cooperative agreement (U01) application, which will support the actual conduct of the study. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-08-003.html
Translation of Common Disease Genetics into Clinical Applications (R21)
The National Institute of Diabetes and Digestive nd Kidney Diseases on behalf of the NIH Genes, Environment and Health Initiative, solicits Exploratory/Developmental Clinical Research Grant (R21) applications from institutions/ organizations that propose a) clinical studies using information from genome wide association or other genetic studies in common diseases; b) development and assessment of diagnostic, clinical trial, epidemiologic and risk analytic tools for use in clinical research or practice; and c) cost-effectiveness studies of clinical applications of genetic information. Areas of interest include, but are not limited to: development of diagnostic or other risk factor algorithms that incorporate genetic data; pilot interventional studies using findings from genetic studies of common diseases or outcomes related to genetic testing for variants identified in common diseases; pilot research on clinical modification of environmental factors known to interact with specific genes variants identified in common diseases; and cost effectiveness studies. The proposed research must focus on using findings from genetic studies of common diseases with complex genetic etiology in clinical or public health settings. Through a Exploratory/Developmental Clinical Research (R21) grant, this FOA will support efforts to produce data that may be useful or pivotal in eventually designing large scale clinical trials or studies. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-08-004.html
Epigenomics of Human Health and Disease (R01)
The National Institutes of Health invites applications that propose research to transform our understanding of the epigenetic contributions to human disease. Studies will characterize global (epigenome-wide) marks or features, and their possible interactions, in cells and tissues that are representative of various human disease states, conditions, or processes. Rather than solely advancing knowledge, "transformation" as defined in this FOA, is intended to change our fundamental understanding of human health and disease by creating a new paradigm or by disrupting an existing one. Unbiased epigenome-wide (global) mapping approaches must be used to identify marks in diseased, aged, or environmentally compromised human primary cells or tissues. Mammalian animal models are allowed in rare exceptions where human samples cannot be obtained for a given disease/condition of interest, but strong justification must be provided. Mapping the epigenome of normal cells will only be permitted as a control for mapping the epigenome of diseased or other aberrant cellular states. Studies may also include follow-up epigenetic approaches to reveal function or significance of target genomic regions or loci identified through the initial mapping.The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-08-017.html
Climate Change and Allergic Airway Disease
The Environmental Protection Agency Office of Research and Development, National Center for Environmental Research, in cooperation with the EPA Global Change Research Program, announces an extramural funding competition supporting research on the impact of global change on the burden of allergic airway disease from exposure to pollen, mold, and other plant-derived allergens. Under the Global Change Research Act of 1990, the United States Climate Change Science Program is required to undertake scientific assessments of the potential consequences of global change for the United States (e.g. Patz et al., 2000). Global changes encompass changes in climate, climate variability, land-use, economic development, population dynamics, and technology advances. EPA is interested in supporting research on the analysis of health outcomes that may be affected by future global changes and fostering a better understanding of the consequences of global change for human health. The complete version of this announcement is available at http://es.epa.gov/ncer/rfa/2008/2008_star_climate_change.html
Exploratory Collaborations with National Centers for Biomedical Computing (R21)
This funding opportunity announcement is for projects from individual-investigators or small groups to collaborate with the NIH Roadmap for Medical Research National Centers for Biomedical Computing (NCBCs). For a description of the NCBCs see http://www.bisti.nih.gov/ncbc/. The intention of the collaborating projects is to engage researchers across the nation in building an excellent biomedical computing environment, using the computational tools and biological and behavioral application drivers of the funded NCBCs as foundation stones. This FOA is intended to support exploratory biomedical informatics and computational biology research—applications should be innovative, with high risk/high impact in new areas that are lacking preliminary data or development. Applications for R21 awards should describe projects distinct from those supported through the traditional R01 mechanism. For example, long-term projects, or projects designed to increase knowledge in a well-established area will not be considered for R21 awards. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-183.html
Collaborations with National Centers for Biomedical Computing (R01)
This funding opportunity announcement is for projects from individual-investigators or small groups to collaborate with the NIH Roadmap for Medical Research National Centers for Biomedical Computing (NCBCs). For a description of the NCBCs see http://www.bisti.nih.gov/ncbc/. The intention of the collaborating projects is to engage researchers across the nation in building an excellent biomedical computing environment, using the computational tools and biological and behavioral application drivers of the funded NCBCs as foundation stones. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-184.html
Outstanding New Environmental Scientist Award (ONES) (R01)
The Outstanding New Environmental Scientist Award is intended to identify outstanding scientists who are in the early, formative stages of their careers and who intend to make a long term career commitment to research in the mission areas of the NIEHS and assist them in launching an innovative research program focusing on problems of environmental exposures and human biology, human pathophysiology and human disease. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-08-003.html
Clinical Centers for the NHLBI Asthma Network (AsthmaNet) (U10)
The purpose of this funding opportunity announcement (FOA), issued by NHLBI, NIH, is to invite applications to participate in the NHLBI Asthma Network (AsthmaNet), a clinical research network that will develop and conduct multiple clinical trials to address the most important asthma management questions and new treatment approaches in pediatric and adult populations. AsthmaNet is designed to promote cooperation and coordination, facilitate scientific exchange, provide training opportunities, and leverage resources. AsthmaNet will include multiple Clinical Centers and one Data Coordinating Center. The protocols will include clinical trials to evaluate and/or compare existing or new therapeutic approaches to asthma management as well as a limited number of proof-of-concept studies to advance the development of novel therapies and studies that investigate the mechanistic bases for interventions examined in AsthmaNet. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-08-010.html
Data Coordinating Center for the NHLBI Asthma Network (AsthmaNet) (U10)
The purpose of this funding opportunity is to invite applications to participate as Data Coordinating Center in the NHLBI Asthma Network (AsthmaNet), a clinical research network that will develop and conduct multiple clinical trials to address the most important asthma management questions and new treatment approaches in pediatric and adult populations. AsthmaNet is designed to promote cooperation and coordination, facilitate scientific exchange, provide training opportunities, and leverage resources. AsthmaNet will include multiple Clinical Centers and one Data Coordinating Center. The protocols will include clinical trials to evaluate and/or compare existing or new therapeutic approaches to asthma management as well as a limited number of proof of concept studies to advance the development of novel therapies and studies that investigate the mechanistic bases for interventions examined in AsthmaNet. The complete version of this announcement is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-08-011.html
Millennium Promise Awards: Non-communicable Chronic Diseases Research Training Program (NCoD) (D43)
This research training program is designed to build research capacity in low- and middle-income countries (LMICs) in the fields related to cancer, cerebrovascular disease including stroke, lung disease including chronic obstructive pulmonary disease (COPD) and environmental factors including indoor air pollution, and obesity and lifestyle factors related to these conditions as well as genetics of non-communicable diseases. The institutions applying can be domestic or foreign, but have to exhibit the ability to do such training, and must exhibit that they have existing research programs in these fields. The complete version of this announcement is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-175.html
Functional Characterization of Genetic Variants and Interactions: The Genes, Environment and Health Initiative (R21)
The National Institute on Drug Abuse on behalf of the NIH Genes, Environment and Health Initiative encourages functional characterization of genetic variants that have been statistically nominated to be associated with a particular outcome through common, complex disease gene discovery approaches, such as genome-wide association studies, candidate gene approaches, or sequencing studies. This FOA supports research relating genetic variation to biological mechanism, or disease causality. Areas of interest include, but are not limited to, relatively low throughput approaches (e.g. transgenic mouse approaches) to test some of the most promising variants for changes in function; or exploit high-throughput tests (e.g. yeast, C. elegans, cell culture systems, or computational approaches) to look at different aspects of variant function.The complete version of this RFA is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-09-003.html
Functional Characterization of Genetic Variants and Interactions: The Genes, Environment and Health Initiative (R03)
The National Institute on Drug Abuse on behalf of the NIH Genes, Environment and Health Initiative encourages functional characterization of genetic variants that have been statistically nominated to be associated with a particular outcome through common, complex disease gene discovery approaches, such as genome-wide association studies, candidate gene approaches, or sequencing studies. This FOA supports research relating genetic variation to biological mechanism, or disease causality. Areas of interest include, but are not limited to, relatively low throughput approaches (e.g. transgenic mouse approaches) to test some of the most promising variants for changes in function; or exploit high-throughput tests (e.g. yeast, C. elegans, cell culture systems, or computational approaches) to look at different aspects of variant function. The complete version of this RFA is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-09-004.html
NIH Support for Conferences and Scientific Meetings (Parent R13/U13)
The purpose of the NIH Research Conference Grant Program (R13 and U13) is to support high quality conferences/scientific meetings that are relevant to the scientific mission of the NIH and to the public health. A conference/scientific meeting is defined as a gathering, symposium, seminar, scientific meeting, workshop or any other organized, formal meeting where persons assemble to coordinate, exchange, and disseminate information or to explore or clarify a defined subject, problem, or area of knowledge. Each NIH Institute and Center (IC) has a scientific purview and different program goals and initiatives that evolve over time. Prior to preparing an application, it is critical that all applicants consult the appropriate IC representative listed in the R13/U13 Website (http://grants.nih.gov/grants/funding/r13/) to obtain current information about IC specific program priorities and policies. This action is of utmost importance because applications with marginal or no relevance to the participating Institutes will not be accepted for review or possible funding. In addition, applicants are encouraged to consult the Frequently Asked Questions Website for more detailed information about this program: http://grants.nih.gov/grants/funding/r13/index.htm The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PA-08-149.html
Midcareer Investigator Award in Patient-Oriented Research (K24)
The purpose of the Midcareer Investigator Award in Patient-Oriented Research is to provide support to mid-career health-professional doctorates or equivalent who are typically at the Associate Professor level or the equivalent (see Section III. Eligible Individuals) for protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty. The intent of this award is two-fold: 1) to enable mid-career clinician scientists to devote more time and to augment their capabilities in patient-oriented research; and 2) to enable mid-career clinical scientists to mentor new clinical investigators in the conduct of patient-oriented research. An award recipient who continues to have an independent peer-reviewed patient-oriented research program and continues to provide mentoring to new investigators can continue to contribute to the overall goals of the program after being promoted to Full professor. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PA-08-151.html
New Technologies for Transient Molecular Complex Characterization (SBIR [R43/R44])
This Funding Opportunity Announcement (FOA) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to develop new technologies, tools, and/or processes for the study of transient molecular complexes. Depending on the complex, such studies should have the potential for characterizing normal function or disease dysfunction and the effects of potential therapeutic interventions. Awards will be used to create new technologies, tools, and/or processes that will help to study transient molecular complexes that are an integral part of normal cell physiology or that play a role in disease processes. Structural (stoichiometry, localization, symmetry, and overall shape) and kinetic characterization of these short-lived complexes will provide insight leading to a better understanding of normal processes and a means to efficiently search for diagnostics or therapeutic interventions for disease conditions. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-110.html
New Technologies for Transient Molecular Complex Characterization (STTR [R41/R42])
This Funding Opportunity Announcement (FOA) solicits Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) that propose to develop new technologies, tools, and/or processes for the study of transient molecular complexes. Depending on the complex, such studies should have the potential for characterizing normal function or disease dysfunction and the effects of potential therapeutic interventions. Awards will be used to create new technologies, tools, and/or processes that will help to study transient molecular complexes that are an integral part of normal cell physiology or that play a role in disease processes. Structural (stoichiometry, localization, symmetry, and overall shape) and kinetic characterization of these short-lived complexes will provide insight leading to a better understanding of normal processes and a means to efficiently search for diagnostics or therapeutic interventions for disease conditions. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-111.html
In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R01)
This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute (NCI), the National Institute of Environmental Health Sciences (NIEHS), and the Office of Dietary Supplements (ODS), encourages innovative preclinical research applications that will enhance the understanding of the relationship between exposure(s) to bioactive food components and/or environmental chemicals in utero, hormonal and growth-factor response, gene expression or epigenetic changes, and subsequent mammary cancer risk in preclinical models. Although much evidence suggests that dietary components are linked to cancer prevention, the specific nutrients, sites of action, and role of exposure in utero remain elusive. Similarly, there are data suggesting a role for environmental agents such as mycotoxins, heterocyclic amines, and environmental chemicals with endocrine activity in the etiology of mammary cancer but the doses, windows of susceptibility, and mechanisms are unclear. This FOA encourages applications that apply new high-throughput genomic, epigenomic, proteomic, and metabolomic technologies to determine how dietary exposures in utero influence adult breast cancer susceptibility. The resulting information will help define effective maternal dietary intervention strategies for breast cancer prevention in her offspring. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PA-08-141.html
In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R21)
This Funding Opportunity Announcement (FOA) issued by the National Cancer Institute (NCI), the National Institute of Environmental Health Sciences (NIEHS), and the Office of Dietary Supplements (ODS), encourages innovative preclinical research applications that will enhance the understanding of the relationship between exposure(s) to bioactive food components and/or environmental chemicals in utero, hormonal and growth-factor response, gene expression or epigenetic changes, and subsequent mammary cancer risk in preclinical models. Although much evidence suggests that dietary components are linked to cancer prevention, the specific nutrients, sites of action, and role of exposure in utero remain elusive. Similarly, there are data suggesting a role for environmental agents such as mycotoxins, heterocyclic amines, and environmental chemicals with endocrine activity in the etiology of mammary cancer but the doses, windows of susceptibility, and mechanisms are unclear. This FOA encourages applications that apply new high-throughput genomic, epigenomic, proteomic, and metabolomic technologies to determine how dietary exposures in utero influence adult breast cancer susceptibility. The resulting information will help define effective maternal dietary intervention strategies for breast cancer prevention in her offspring. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PA-08-141.html
Genetic Screens to Enhance Zebrafish Research (R01)
This FOA encourages investigator-initiated applications designed to exploit the power of the zebrafish as a ertebrate model for biomedical and behavioral research. Applications proposing to develop new genetic screens of high priority to the zebrafish community that will advance the detection and characterization of genes, pathways, and phenotypes of interest in development and aging, organ formation, neural processes, behavior, sensory processes, physiological processes, and disease processes are welcome. This effort stems from an NIH initiative developed by the Institutes and Centers of the Trans-NIH Zebrafish Coordinating Committee (TZCC) under the co-chairmanship of NICHD and NIDDK. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-138.html
Enhancing Zebrafish Research with Research Tools and Techniques (R01)
This FOA encourages investigator-initiated applications designed to exploit the power of the zebrafish as a vertebrate model for biomedical and behavioral research. Applications proposing to develop new research tools or techniques that are of high priority to the zebrafish community and that will advance the detection and characterization of genes, pathways, and phenotypes of interest in development and aging, organ formation, neural processes, behavior, sensory processing, physiological processes, and disease processes are welcome. This effort stems from an NIH initiative developed by the Institutes and Centers of the Trans-NIH Zebrafish Coordinating Committee (TZCC) under the co-chairmanship of NICHD and NIDDK. The complete version of this PA is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-139.html
Probes and Instrumentation for Monitoring and Manipulating Nervous System Plasticity (R01)
This Funding Opportunity Announcement (FOA) is issued as an initiative of the NIH Blueprint for Neuroscience Research. The Neuroscience Blueprint is a collaborative framework through which 16 NIH Institutes, Centers and Offices jointly support neuroscience-related research, with the aim of accelerating discoveries and reducing the burden of nervous system disorders (for further information, see http://neuroscienceblueprint.nih.gov/). Applications are solicited for support of projects that will develop probes, instrumentation, and other tools for understanding, monitoring, and manipulating nervous system plasticity. This FOA will focus on the development of tools or techniques that will significantly advance the current state of the art in neuroplasticity research. Although applications will not be restricted to a particular type of technology, we are especially interested in applications that seek to harness the ability to assess and manipulate activity with exquisite subcellular resolution, and in cells specified by their circuit connectivity and/or transmitter phenotype. The complete version of this RFA is available at: http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-09-030.html
The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R01)
The purposes of this FOA are to: 1) improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection, and statistical/analytical techniques; 2) enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment, and outcomes among disadvantaged racial/ethnic minority groups; and 3) reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination in health care delivery systems in the United States (U.S.).
For the purposes of this FOA, health care delivery is defined as the provision or receipt of a broad range of health-related services including preventive, primary, ambulatory and in-patient, emergency, specialty and long-term care. Health care delivery systems are defined as insurance plans, hospitals, clinics, private physician offices, or public and community health facilities that provide or finance health care delivery. The complete version of the PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-083.html
The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R21)
The goals of this funding opportunity are to: 1) improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection, and statistical/analytical techniques; 2) enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment, and outcomes among disadvantaged racial/ethnic minority groups; and 3) reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination in health care delivery systems in the United States (U.S.).
For the purposes of this FOA, health care delivery is defined as the provision or receipt of a broad range of health-related services including preventive, primary, ambulatory and in-patient, emergency, specialty and long-term care. Health care delivery systems are defined as insurance plans, hospitals, clinics, private physician offices, or public and community health facilities that provide or finance health care delivery. The complete version of the PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-084.html
The Effect of Racial and Ethnic Discrimination/Bias on Health Care Delivery (R03)
The goals of this funding opportunity are to: 1) improve the measurement of racial /ethnic discrimination in health care delivery systems through improved instrumentation, data collection, and statistical/analytical techniques; 2) enhance understanding of the influence of racial/ethnic discrimination in health care delivery and its association with disparities in disease incidence, treatment, and outcomes among disadvantaged racial/ethnic minority groups; and 3) reduce the prevalence of racial/ethnic health disparities through the development of interventions to reduce the influence of racial/ethnic discrimination in health care delivery systems in the United States.
For the purposes of this FOA, health care delivery is defined as the provision or receipt of a broad range of health-related services including preventive, primary, ambulatory and in-patient, emergency, specialty and long-term care. Health care delivery systems are defined as insurance plans, hospitals, clinics, private physician offices, or public and community health facilities that provide or finance health care delivery. The complete version of the PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-085.html
Pfizer Scholars Grants in Public Health - Junior Faculty Pursuing Community-Based, Public Health Practice Research
Pfizer Inc is proud to sponsor the Pfizer Scholars Grants in Public Health. These awards are meant to support the career development of junior faculty in public health. This educational grant is nationally competitive, and chosen by an independent Academic Advisory Board of recognized leaders in public health. More information is available at http://www.promisingminds.com/AwardDetails.asp x?AwardID=2081
Community Participation in Research (R01)
The National Institutes of Health (NIH) issues this Funding Opportunity Announcement (FOA) to solicit research project (R01) grant applications that propose intervention research on health promotion, disease prevention, and health disparities that communities and researchers jointly conduct.
Community-based participatory research (CBPR) is defined as scientific inquiry conducted in communities and in partnership with researchers. The process of scientific inquiry is such that community members, persons affected by the health condition, disability or issue under study, or other key stakeholders in the community's health have the opportunity to be full participants in each phase of the work (from conception – design – conduct – analysis –interpretation – conclusions – communication of results). CBPR is characterized by substantial community input in the development of the grant application (http://odoerdb2-1.od.nih.gov/oer/training/esaig/cbprsig_IG.htm).
For the purposes of this FOA, intervention research is quasi-experimental research projects that seek to influence preventive behaviors, treatment adherences, complementary behaviors, and related attitudes and beliefs. Natural experiments also may fall under the interventions rubric. Examples include, and are not limited to promotion of physical activity-friendly neighborhoods; tobacco, alcohol and drug abuse prevention among youth; a community-led action plan for cancer, hypertension and cardiovascular disease prevention and control in minority populations; establishing safer work practices among agricultural workers in rural areas; nutrition and reducing childhood obesity; HIV/AIDS and STD prevalence among young adults; promoting infant mental health; and reducing health disparities. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-074.html.
Community Participation Research Targeting the Medically Underserved (R01)
The National Institutes of Health (NIH) issues this Funding Opportunity Announcement (FOA) with a special review to solicit research project (R01) grant applications that propose research on health promotion, disease prevention, and health disparities that is jointly conducted by communities and researchers and targets medically underserved areas (MUAs) and medically underserved populations (MUPs) as defined by the Department of Health and Human Services (DHHS) Health Resources and Services Administration (HRSA).
Community-based participatory research (CBPR) is defined as scientific inquiry conducted in communities and in partnership with researchers. The process of scientific inquiry is such that community members, persons affected by the health condition, disability or issue under study, or other key stakeholders in the community's health have the opportunity to be full participants in each phase of the work (from conception – design – conduct – analysis – interpretation – conclusions – communication of results). CBPR is characterized by substantial community input in the development of the grant application (http://odoerdb2-1.od.nih.gov/oer/training/esaig/cbprsig_IG.htm). The complete version of this PAR is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-075.html
Community Participation Research Targeting the Medically Underserved (R21)
The National Institutes of Health (NIH) issues this Funding Opportunity Announcement (FOA) with a special review to solicit exploratory/developmental (R21) grant applications that propose research on health promotion, disease prevention, and health disparities that is jointly conducted by communities and researchers and targets medically underserved areas (MUAs) and medically underserved populations (MUPs) as defined by the Department of Health and Human Services (DHHS) Health Resources and Services Administration (HRSA).
Community-based participatory research (CBPR) is defined as scientific inquiry conducted in communities and in partnership with researchers. The process of scientific inquiry is such that community members, persons affected by the health condition, disability or issue under study, or other key stakeholders in the community's health have the opportunity to be full participants in each phase of the work (from conception – design – conduct – analysis – interpretation – conclusions – communication of results). CBPR is characterized by substantial community input in the development of the grant application (http://odoerdb2-1.od.nih.gov/oer/training/esaig/cbprsig_IG.htm). The complete version of this PAR is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-076.html
The Science and Ecology of Early Development (SEED) [R03]
SCOPE: The common characteristic of the small grant is provision of limited funding for a short period of time. Examples of the types of projects that ICs support with the R03 include the following:
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Pilot or feasibility studies
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Secondary analysis of existing data
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Small, self-contained research projects
This Funding Opportunity Announcement (FOA), jointly issued by the Child Development and Behavior Branch (CDBB) and the Demographic and Behavioral Sciences Branch (DBSB) of the National Institute of Child Health and Human Development (NICHD), Division of Epidemiology, Services and Prevention Research of the National Institute on Drug Abuse (NIDA), and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), invites research grant applications that seek to develop or contribute to a comprehensive program of research focused on the mechanisms through which social, economic, cultural, familial and community-level factors, and their interactions, impact the early cognitive, neurobiological, socio-emotional, and physical development of children. Understanding the influence of these mechanisms and the pathways by which they operate is especially important for understanding the impact of available services and the public policies which govern them on the development of children at whom (or at whose families) these policies are often specifically targeted, notably children living in poverty or near the federal poverty line. Arenas of particular relevance include childcare, early childhood education, welfare reform, tax, social services, and work-family policies, as all of these shape the life experiences of children in poverty. Thus, the goal is to generate solid scientific information that would bear directly on these arenas and thus inform policies and the design of service delivery programs that impact child development, whether or not child development is the explicit focus of those policies and services. This FOA extends the seven-year Science and Ecology of Early Development (SEED) initiative and is the outgrowth of an interagency collaborative effort from 2000 through 2004 among the following agencies: 1) U.S. Department of Health and Human Services [NICHD, National Institute of Mental Health (NIMH), NIDA, Administration for Children and Families (ACF), Office of the Assistant Secretary for Planning and Evaluation (ASPE), and the Centers for Disease Control and Prevention (CDC)], and 2) the Department of Education (National Center for Education Statistics, National Center for Education Research, and the National Center for Special Education Research in the Institute of Education Sciences). These agencies have pursued other avenues of supporting research on this topic. NICHD and NIDA have continued to collaborate on this Funding Opportunity Announcement. Details of that earlier initiative can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06-345.html and http://grants.nih.gov/grants/guide/pa-files/PA-07-149.html. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-068.html.
Nanoscience and Nanotechnology in Biology and Medicine (R01)
Nanoscience and nanotechnology refer to the understanding and control of matter at the atomic, molecular or macromolecular levels, at the length scale of approximately 1–100 nanometers. The purpose of this funding opportunity is to stimulate nanoscience and nanotechnology research approaches that have the potential to make valuable contributions to biology and medicine. Nanoscience and nanotechnology can bring fundamental changes to the study and understanding of biological processes in health and disease, as well as enable novel diagnostics and interventions for treating disease. Thus, advances based on nanotechnology and nanoscience could result in a new era in healthcare. The complete version of this PA is available at http://grants.nih.gov/grants/guide/pa-files/PA-08-052.html.
Predictive Multiscale Models of the Physiome in Health and Disease (R01)
The goal of this solicitation is to move the field of biomedical computational modeling forward through the development of more realistic and predictive models of health and disease. NIH recognizes the need for sophisticated, predictive, computational models of development and disease that encompass multiple biological scales. These models may be designed to uncover biological mechanisms or to make predictions about clinical outcome and may draw on a variety of data sources including relevant clinical data. Ultimately the models and the information derived from their use will enable biomedical and behavioral researchers and clinicians to better understand, prevent, diagnose and treat the diseases or aberrations in normal development. Specifically this FOA seeks the development of biomedical models that are 1) multiscale, 2) predictive of health and disease states, and 3) that must include models at higher scales of the physiome. The complete version of this PAR is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-08-023.html
NIAID Science Education Awards (R25)
This funding opportunity announcement (FOA) solicits applications from applicant organizations that propose creative and innovative research education programs that will 1) increase the public's understanding of biomedical research, or 2) encourage K-12 students to enter areas in biomedical science in the mission area(s) of the National Institute of Allergy and Infectious Diseases (NIAID). The NIH Research Education (R25) grant mechanism is a flexible and specialized mechanism designed to foster the development of biomedical, behavioral, and clinical researchers through creative and innovative research education programs. The complete version of this PAR is available at http://grants.nih.gov/grants/guide/pa-files/PAR-08-003.html.
