Highlights
Biological Sciences Division
2008
Research Highlights
- New Data Analysis Tools Advance Protein Research (September)
- Review Article Chronicles Research on Versatile Bacterium (September)
- New SPIN Corrals Protein Molecules (August)
- Now It's Molecular: New Understanding of Radiation Effects on Cells (August)
- New Technology Provides Accurate, Noninvasive Look at Microbial Metabolism (July)
- Proteins under pressure (July)
- Mobile Elements and Pseudogenes Identified in Shewanella Oneidensis MR-1 (July)
- Molecular-level Analyses Reveal Possible Mechanisms Underlying Parkinson's Disease (May)
- Protein Research Uncovers Surprising Similarities in Diverse Bacteria (May)
- Assigning Proteins ID Cards (May)
- Tissue proteomics targets blood test for breast cancer (May)
- New Technology Enables Better Understanding of Brain Development (April)
- Microbe-Metal Interaction Yields Novel Mineral Nanostructures (April)
- FCSD and EMSL Team to Develop a Transformational Next-Generation Proteomics Measurement Platform (April)
- Cavities Beware! (April)
- Unlocking the Secrets of the Secretome (April)
- X-ray Crystallography Reveals New Insights into Pentapeptide Repeat Protein Structure (February)
- Biomarkers for Type 1 Diabetes Found Using Proteomics (February)
- Proteins Provide Clues to Nanomaterial Toxicity (February)
- New NMR Method to Characterize Proteins (February)
- Regulatory Protein Shown to Indicate Stress in Skeletal Muscle (January)
- BioPilot: Data Intensive Computing for Complex Biological Systems (January)
2008
Staff Awards & Honors
- Allan Konopka Joins Laboratory Fellow Ranks (August)
- Eminent Radiation Biology Researcher Joins PNNL (August)
- Karin Rodland selected as Laboratory Fellow (August)
- PNNL Researcher Named to NAS Nanoscience Review Committee (May)
- Tom Metz Named to Proteomic Insights Editorial Board (May)
- Metting Appointed to Fourth Term on Oregon Bioscience Association Board (May)
- Keqi Tang Chosen 2007 PNNL Inventor of the Year (April)
- Pounds and Weber Receive Appointments to Toxicology Society (April)
- International Scientific Collaboration Earns Honorary Professorship (April)
- Mass Spec Manuscript Heads Top 25 Hottest Articles List (March)
- Authors Clamor To Read, Cite Article on Nanowires in Bacteria (January)
2007
Research Highlights
- Shewanella Shows Cytochromes Convert Contaminant (December)
- Dick Smith Named to Prestigious 2007 Scientific American 50 List (December)
- Compilation of Fundamental Science Accomplishments Now Available (December)
- Comprehensive Whole-Proteome Analysis Now Available to Scientific Community (November)
- Radionuclide Monitors Being Developed Through Partnership Between PNNL ERSP Researchers and Small Business (October)
- NIH Funds New Biomarkers Center at PNNL (October)
- A New Fluorescent Probe for Protein Interactions (July)
- Researchers Develop, Improve and Enhance Technologies for Rapid Analysis of Complex Samples (June)
- New View on Radiation-Resistant Microbe (June)
- A New Systems Strategy to Study Cell Surface Receptor Dynamics (June)
- First Comprehensive Profile of Cell Movement Created by PNNL, UCSD (May)
- Nanobiotechnology Research Featured in Prominent Journals (May)
- Changes in Environmental Conditions Impact Cell Function (April)
- Improved Methods for Nanoparticle Toxicity Research (April)
- 3-D Cultures Help Identify, Screen Noroviruses (April)
- Novel Trafficking Pathway Found for Heart and Muscle Protein (March)
- Mass Spectrometry Capabilities Aid in Large Poxvirus Study (March)
2007
Staff Awards & Honors
- Dave Koppenaal Named AAAS Fellow (November)
- Dick Smith Elected to HUPO Council (November)
- Qian honored with Ronald L. Brodzinski Award for Early Career Exceptional Achievement (October)
- Romine Gives Seminar at 100th Genome Celebration (May)
- Konopka Named Microbiology Group Lead (March)
- Two Journal Articles Make ACS Most-Cited List (March)
- Vanessa Bailey Joins Editorial Board of Soil Biology and Biochemistry (March)
- Metting Named Chair of International Scientific Network (February)
2006
Research Highlights
- PNNL to Manage Two DOE Field Research Sites for Studying Contaminant Transport (December)
- Cytochrome Studies Provide Biofuel Cell Potential (November)
- Studies of Corrosion-Causing Bacterium Shed New Light on Decay Mechanisms (November)
- Plague Proteome Reveals Proteins Linked to Infection (November)
- PNNL, Agilent CRADA Sgned for Proteomic Research (October)
- PNNL Wins Project BioShield Grants (October)
- Chromate Immobilization Success Leads to More Field Tests for Effective, Long-Lived Contaminant Barriers (October)
- First Use of Global Proteomics to Quantify Bacterial Proteins Isolated from Host Cells (October)
- PNNL Staff Support Breast Cancer Research Awareness (October)
- DOE Awards PNNL Contract for Single-Molecule Studies of Enzymes (August)
- Shewanella Uranium Reduction Role Described in PLoS Article (August)
- Novel Bug Work Appears in Two Journals (August)
- PNNL Featured in C&E News Sys Bio Cover Story (August)
- PNNL Scientists Improve Quality of Global Transcriptome Studies (August)
- Improved sensors developed for long-term groundwater monitoring at DOE sites (July)
- PNNL Team Makes the First Global Identification of Endogenous Levels of Nitrated Proteins in the Brain (July)
- New Insights Made into the Functioning of Deep Subsurface Microbial Communities (June)
- Open-source Software Tool for Protein Microarray Analysis Available from PNNL (June)
- Live Wires: A microbiologist discovers our planet is hard-wired with electricity-producing bacteria (June)
- Second Phase of PNNL Diabetes Research Funded by NIH (June)
- Combined Methods Meet Challenge of Studying Protein Changes (June)
- Illuminating the Mechanism of Fluorophore-assisted Light Inactivation of Proteins (June)
- Systems Biology Article Appears in The Scientist (June)
- Better Proteomic Measurements Achieved with Smaller Liquid Chromatography Columns (June)
- Isolation and Validation of a Metal-reducing Protein Complex from Shewanella published in the Journal of Bacteriology (June)
- New Role Discovered for Calmodulin: Modulating Inflammatory Response (June)
- Researchers develop improved protein affinity probe (May)
- Researchers Develop Improved Protein Affinity Probe (May)
- Firsts in Mouse and Mammalian Brain Proteomic Research Featured in Journal (April)
- First Study on the Mitochondrial Outer Membrane Subproteome Appears in Proteomics (April)
- PNNL Wins NCI Contract for Breast Cancer Biomarker Research (April)
- First Constraint-Based Metabolic Model for an Archaea to be Published in Nature Reviews Molecular Systems Biology (January)
2006
Staff Awards & Honors
- Noted Radiation Biology Researcher Named PNNL Affiliate Scientist (December)
- Dick Smith Named AAAS Fellow (December)
- Jim Fredrickson Named AAAS Fellow (December)
- Proteomic Poster Wins Award at International Proteome Meeting (November)
- Adkins Honored with Lab Director's Award for Exceptional Achievement (October)
- Fredrickson Appointed to Mars Committee (July)
- Ellis Appointed to Canadian NMR Advisory Board (June)
- Hoyem Named PNNL Administrator of the Year (June)
- Ray Wildung Joins Biological and Environmental Research Advisory Committee (April)
- Fredrickson Named GTL Chief Scientist (February)
2005
Research Highlights
- Cutting-edge proteomics tool featured in two Analytical Chemistry articles (December)
- Mass spectrometry detectors—eye on ions (November)
- Rodland speaks at breast cancer forum in Olympia (November)
- Low-dose work highlighted in three journal articles (November)
- Journal lists two PNNL articles in top five most accessed (November)
- Imaging system success story featured on journal cover (September)
- NMR technologies developed for biofilm studies featured in recent journals (September)
- Carbon tetrachloride and chloroform accumulate and resist migration in Hanford aquifer sediments (September)
- Novel sensor for technetium applicable to Hanford and other DOE sites (September)
- Ellis contributes to National Academies' report (September)
- DOE review of proteomic informatics capability given high marks (July)
- PNNL part of NIH protein production center contract (July)
- Simulation of PNNL protein identification process featured in journal special edition (July)
- NMR study of DNA repair protein dynamics featured on journal covers (June)
- Ultra-high performance separations and mass spectrometry work featured in IJMS (June)
- Automated, high-throughput protein pipeline in place at PNNL (June)
- PNNL receives NIH funding to model bacterial membrane proteins and human cell signaling networks (June)
- Study of rare tautomers featured on journal cover (May)
- A fluorescent probe finds a second use in a resin for protein pull-downs (May)
- New biological consortium featured in The Scientist (May)
- PNNL NCRR Proteomics Research Resource hosts national workshop (May)
- Collaborative research published in PNAS focuses on skeletal muscle cell understanding (May)
- PNNL sponsors seminar at annual AAAS meeting on high-throughput biological data (April)
- Shewanella profiling paper appears in PNAS (April)
- Proteomics Resource Advisory Committee held yearly meeting at EMSL (February)
- PNNL to play key role in RTK Consortium (February)
- Enhanced Soil Carbon Sequestration Evaluation Methods Reviewed in Journal Article (February)
- Identifying shed and secreted proteins by mass spectrometry after exposure of CHO cells to low-dose radiation (February)
- Enhanced yellow fluorescent protein enables definition of bystander-specific transformation response (January)
2005
Staff Awards & Honors
- Wiley named AAAS Fellow (November)
- Wiley named to editorial board of The Scientist (September)
2004
Research Highlights
- Cellular Response to Protein Nitration in C2C12 Myocytes Detected with Complementary Approaches: Cell Biology and Global Proteomic Screens (December)
- Mechanisms of 3D intercellular signaling in mammary epithelial cells in response to low dose, low-LET radiation: Implications for the radiation-induced bystander effect (November)
- NABIR project demonstrates that uranium remains immobile one year after wells were injected with acetate (November)
- PNNL to receive NIH contract for proteomic studies of potential therapeutic targets (October)
- Bystander Effects in Cells Exposed to Low Dose Radiation: Identifying Shed Proteins by Mass Spectrometry and Statistical Confidences (October)
- Pacific Northwest team unveils largest virus proteome to date (September)
- Peering inside the body, with a new spin-literally (September)
- PNNL lands $10.3 million NIH biodefense contract to unlock proteomes of salmonella and pox (September)
- NMR Spectroscopic Investigation of Human Carbonic Anhydrase Points to Alternative Mechanism of Action (July)
- Most complete human blood-plasma proteome to date (June)