A multispectral, multi-resolution (MSMR) method is developed for analyzing scenes of overlapping cloud layers. The MSMR method is applied to data from the NOAA 11 advanced very high-resolution radiometer (AVHRR) and the high0resolution infrared radiometer sounder (HIRS-2). The data are from a nighttime oceanic scene in which a semi-transparent cirrus veil overlays a larger scale stratus cloud. Low-cloud and clear-sky radiances are determined using a spatial coherence technique. Middle to upper level cloud pressures and radiances are estimates from HIRS02 15-µm CO2 band radiometric data. The MSMR method improves the interpretation of a nighttime, oceanic scene containing thin cirrus over a large-scale stratiform cloud. If, for example, the same scene is analyzed using only the AVHRR 10.8-µm channel, the accompanying retrieved cloud heights are found to be between the cirrus and stratus cloud heights and are incorrectly identified as midlevel altostratus clouds. Theoretical radiative transfer model results or both water droplet spheres and randomly oriented hexagonal ice crystals are compared to observed AVHRR brightness temperature differences (BTD) between the 3.7- and 10.8-µm channels (BTD34) and between the 10.8- and 12-µm channels (BTD45) to distinguish among the effects of cloud optical depth, particle, size, and phase for both single-layer clouds and overlapping two-layer clouds. Theoretical BTD calculations are used to estimate the range of effective particle sizes for each cloud layer. The data for the cirrus in the case study region near Bermuda are consistent with theoretical results for relatively small randomly oriented hexagonal ice crystals. The observed BTD34 and BRTD45 values are lower for the cirrus above a lower-level cloud than for single-level cirrus with no underlying cloud. In certain cases the BTD analysis provides a way to distinguish between clouds composed of supercooled water droplets rather than ice particles. Analysis of nighttime data permits determination of stratus infrared optical depths smaller than 4.