Definition of premature ovarian failure - NCI Dictionary of Cancer Terms

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premature ovarian failure (PREE-muh-CHOOR oh-VAYR-ee-un FAYL-yer)

A condition in which the ovaries stop working before age 40. Symptoms include hot flashes, mood swings, night sweats, vaginal dryness, and infertility. Some cancer treatments, such as chemotherapy, radiation therapy, and surgery can cause premature ovarian failure. Ovarian failure caused by cancer treatment may be temporary or permanent and may be treated with hormone replacement therapy. Also called primary ovarian insufficiency or early menopause.

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