Definition of dornase alfa inhalation solution - NCI Dictionary of Cancer Terms

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dornase alfa inhalation solution (DOR-nayz AL-fuh in-huh-LAY-shun suh-LOO-shun)

A drug given in an aerosol mist to decrease the thickness of mucus in the lungs of patients with cystic fibrosis. It is also being studied as a treatment to reduce the thickness of saliva in patients being treated for head and neck cancer. Dornase alfa inhalation solution contains an enzyme that breaks the DNA in mucus into small pieces and makes the mucus thinner. Also called Pulmozyme.

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