Definition of CC49-streptavidin - NCI Dictionary of Cancer Terms

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CC49-streptavidin

A substance that is being studied in the treatment of cancer. It is made by combining the monoclonal antibody CC49 with a chemical called streptavidin. It can find tumor cells that have the protein TAG-72 on their surface, including colon, prostate, breast, and ovary cancer cells. After CC49-streptavidin binds to cancer cells, a radioactive compound called yttrium Y 90 DOTA-biotin will find those cells and kill them.

Previous Definitions:	CC-1088, CC-4047, CC-49, CC-5013, CC-8490
Next Definitions:	CCI-779, cCLB8, CD134, CD34 antigen, CD40-ligand