This is a summary of the most important information about Vaprisol.
For details, talk to your healthcare professional.
What Is Vaprisol?
Vaprisol is a medicine given in a vein (intravenous or I.V.) to
raise low blood sodium levels in hospitalized patients with
“euvolemic hyponatremia.” Euvolemic hyponatremia is when a patient
has too little sodium in the bloodstream but a normal amount of
fluid in the body.
Vaprisol should not be used to treat congestive heart failure.
Vaprisol has not been studied in children.
Who Should Not Be Treated With Vaprisol?
You should not be treated with Vaprisol if you:
- Have too little sodium in the bloodstream and too little fluid
in the body (hypovolemic hyponatremia)
- are allergic to any of its ingredients
- are taking medicines that can interact with Vaprisol, such as:
- statin medicines, including:
- simvastatin (Zocor, Vytorin)
- lovastatin (Mevacor, Altocor, Advicor, Altoprev)
- atorvastatin (Lipitor)
- rosuvastatin (Crestor)
- ketoconazole (Nizoral)
- itraconazole (Sporanox)
- clarithromycin (Biaxin)
- ritonavir (Norvir, Kaletra)
- indinavir (Crixivan)
Know the medicines you take. Keep a list of them with you to show
your healthcare professional.
What Are The Risks?
The following are the major potential risks and side
effects of Vaprisol therapy. This is not a complete list.
- There may be serious side effects if your blood sodium
levels rise too quickly. Your healthcare professional will
monitor your blood sodium levels and check for brain side effects.
- Injection site reactions are the most common side
effect of Vaprisol. Serious injection site reactions may require
stopping Vaprisol.
- Some other common side effects that may occur with
Vaprisol include:
- headache
- thirst
- low potassium
- vomiting
- increased urination
- diarrhea
- decrease in blood pressure upon standing that may cause
faintness
What Should I Tell My Healthcare Professional?
Before you are given Vaprisol, tell your healthcare
professional if you:
- have congestive heart failure
- have or had liver problems
- have or had kidney problems
- are pregnant or are trying to become pregnant
- are breast-feeding
How Is Vaprisol Given?
Vaprisol is given through a large vein (I.V.) for
up to four days.
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