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DCB - Cancer Immunology and Hematology Branch (CIHB)


The Cancer Immunology and Hematology Branch (CIHB) supports a broad program of investigator-initiated research that includes basic and tumor immunology and the biology of malignancies of the immune system (leukemias and lymphomas). Areas of major interest include the immune response to tumors, receptor biology/signal transduction, cytokines, antibodies and antibody genes, T-cell biology, the biology of antigen-presenting cells and nonspecific effectors of the immune system such as natural killer cells, granulocytes and macrophages, hematopoietic differentiation, oncogenes, the biology of hematopoietic tumors (including AIDS lymphomas), and immunologic aspects of bone-marrow transplantation.


Program Announcements and Request for Application

 

 PA-05-086 -Stem Cells and Cancer (R01)
 PA-06-282 -Stem Cells and Cancer (R21)
 PA-06-289 -Immunoregulation of Gastrointestinal Carcinogenesis (R01)
 PA-06-290 -Immunoregulation of Gastrointestinal Carcinogenesis (R21)
 PA-06-349 -Memory T Lymphocytes in Cancer Immunology (R21)
 PA-06-350 -Memory T Lymphocytes in Cancer Immunology (R01)
 
STAFF
NameTitle
 Mufson, R. Allan, Ph.D. Chief
 Howcroft, Kevin, Ph.D. Program Director
 McCarthy, Susan, Ph.D. Program Director
 Duglas-Tabor, Yvonne Program Assoc. Director
 Uzzell, Norwood Extramural Support Asst.
>>NEWSLETTERS<<
Cellular Immunology
The Cellular Immunology program area supports research on the different cells that play a role in the immune response to tumors. These include T and B lymphocytes, macrophages, dendritic cells, natural killer cells, and granulocytes. This Program also supports research on the basic biology of AIDS lymphomas.

Molecular Immunology
The Molecular Immunology program area, directed by Dr. Susan McCarthy, supports research on genes and proteins of potential importance in the immune response to tumors. These include, for example, tumor antigens, cytokines, and cell-associated molecules critical for immune responses, including cell-surface receptors, signal-transduction molecules, and transcription factors necessary for immune-cell activation, proliferation and cytotoxicity. This program also supports research on immunologic aspects of bone-marrow transplantation.

Hematopoiesis and Hematopoietic Malignancies
The Hematopoiesis and Hematopoietic Malignancies program area, directed by Dr. Allan Mufson, supports research on the basic biology of leukemias and lymphomas, and the elements of hematopoeitic differentiation that are relevant to understanding how these malignancies arise. Areas of major interest include myeloid and early lymphoid differentiation, oncogenes, cytokine regulation of gene expression/cell cycle, and cytokine signal transduction.

Conference and SBIR/STTR Grants
Conference Grants and SBIR/STTR Grants, administered by Ms Yvonne Duglas-Tabor support investigator-initiated activities designed to expand the impact and scope of research areas targeted by the CIHB. Conference Grants provide opportunities for researchers to share research results and to develop new research collaborations. SBIR/STTR Grants provide opportunites for development of new technologies with commercial potential relevant to the research areas supported by the CIHB.



 

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