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Proteomics

Photo: Jim Fredrickson

Review Article Chronicles Research on Versatile Bacterium

A microbe that mediates carbon and metal cycling in stratified marine and freshwater environments and serves as a model microbe for systems biology research is highlighted in a review article in Nature Reviews Microbiology... More


Photo: Ashoka Polpitiya

New Data Analysis Tools Advance Protein Research

From developing viable bioenergy to detecting disease, proteins are crucial structural and functional elements to all biological functions. Proteomics experts from Pacific Northwest National Laboratory and two universities have collaborated to develop and deploy data analysis tools to further the field of protein research. Two of these tools are now available free of charge through publicly available websites... More


Photo: Jason Page

New SPIN Corrals Protein Molecules

When studying the proteins in pre-cancerous or other cells, researchers don't have a lot of material—just the contents of a few cells. When they add a sample to the mass spectrometer, the workhorse of protein studies, they don't want to waste any. That's where SPIN comes in. Developed by a research team at Pacific Northwest National Laboratory, SPIN greatly increases the ability of mass spectrometers to analyze cell proteins and other extremely small samples... More


Photo: Allan Konopka

Allan Konopka Joins Laboratory Fellow Ranks

Dr. Allan Konopka, head of the microbiology group at Pacific Northwest National Laboratory, has been named Laboratory Fellow, the highest rank that PNNL science and engineering staff can attain. Konopka, who was honored August 6 at a ceremony at PNNL, is an internationally known microbial ecologist... More


Photo: Protein Abundance changes chart

Now It's Molecular: New Understanding of Radiation Effects on Cells

In recent proteomics studies on radiation effects on cells, new molecular data indicates that dysfunctional mitochondria cause elevated reactive oxygen species in the offspring of cells that survived radiation exposure. These results bring molecular-based evidence to a previously cell-based area of radiation research. The results appear in the June 2008 issue of Radiation Research... More


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