Cyanazine (CASRN 21725-46-2)
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0145
Cyanazine;
CASRN 21725-46-2
Health assessment information on a chemical substance is included in IRIS
only after a comprehensive review of chronic toxicity data by U.S. EPA
health scientists from several Program Offices and the Office of Research
and Development. The summaries presented in Sections I and II represent
a consensus reached in the review process. Background information and
explanations of the methods used to derive the values given in IRIS are
provided in the Background Documents.
STATUS OF DATA FOR Cyanazine
File First On-Line 03/31/1987
Category (section) |
Status |
Last Revised |
---|---|---|
Oral RfD Assessment (I.A.) | withdrawn | 03/01/1996 |
Inhalation RfC Assessment (I.B.) | no data | |
Carcinogenicity Assessment (II.) | no data | 07/01/1993 |
_I. Chronic Health Hazard Assessments for Noncarcinogenic Effects
_I.A. Reference Dose for Chronic Oral Exposure (RfD)
Substance Name — Cyanazine
CASRN — 21725-46-2
Primary Synonym — Bladex
The Oral RfD for cyanazine has been withdrawn on 07/01/1992 as a result of
further review. A new RfD summary is in preparation by the RfD/RfC Work
Group.
Agency Work Group Review — 10/09/1985, 07/08/1986, 05/25/1988, 05/27/1992
Screening-Level Literature Review Findings — A screening-level review conducted by an EPA contractor of the more recent toxicology literature pertinent to the RfD for Cyanazine conducted in September 2002 identified one or more significant new studies. IRIS users may request the references for those studies from the IRIS Hotline at hotline.iris@epa.gov or (202)566-1676.
EPA Contacts:
Please contact the IRIS Hotline for all questions concerning this assessment or IRIS, in general, at (202)566-1676 (phone), (202)566-1749 (FAX) or hotline.iris@epa.gov (internet address).
_I.B. Reference Concentration for Chronic Inhalation Exposure (RfC)
Substance Name — Cyanazine
CASRN — 21725-46-2
Primary Synonym — Bladex
Not available at this time.
_II. Carcinogenicity Assessment for Lifetime Exposure
Substance Name — Cyanazine
CASRN — 21725-46-2
Primary Synonym — Bladex
Not available at this time.
_III.
[reserved]
_IV. [reserved]
_V. [reserved]
_VI. Bibliography
Substance Name — Cyanazine
CASRN — 21725-46-2
Primary Synonym — Bladex
Not available at this time.
_VII. Revision History
Substance Name — Cyanazine
CASRN — 21725-46-2
Primary Synonym — Bladex
Date |
Section |
Description |
---|---|---|
03/01/1988 | I.A.4. | Core grade added |
03/01/1988 | I.A.5. | Confidence levels revised |
06/30/1988 | I.A. | Withdrawn; new RfD verified (in preparation) |
08/22/1988 | I.A. | Revised oral RfD summary added |
01/01/1990 | I.A. | Principal study citation corrected |
01/01/1990 | VI. | Bibliography on-line |
05/01/1990 | I.A.4. | Corrected dose level designations in study 3) |
04/01/1991 | I.A. | Text edited |
01/01/1992 | IV. | Regulatory actions updated |
07/01/1992 | I.A. | Withdrawn; new assessment in preparation |
07/01/1992 | VI.A. | Oral RfD references withdrawn |
07/01/1993 | II. | Carcinogenicity assessment now under review |
08/01/1995 | I.A., II., VI.A. | EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995 |
03/01/1996 | I.A. | Contact changed |
04/01/1997 | III., IV., V. | Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information. |
12/03/2002 | I.A. | Screening-Level Literature Review Findings message has been added. |
_VIII. Synonyms
Substance Name — Cyanazine
CASRN — 21725-46-2
Primary Synonym — Bladex
Last Revised — 03/31/1987
- 21725-46-2
- Bladex
- BLADEX 80WP
- 2-CHLORO-4-(1-CYANO-1-METHYLETHYLAMINO)-6-ETHYLAMINO-1,3,5-TRIAZINE
- 2-(4-CHLORO-6-ETHYLAMINO-1,3,5-TRIAZINE-2-YLAMINO)-2-METHYLPROPIONITRILE
- 2-(4-CHLORO-6-ETHYLAMINO-s-TRIAZINE-2-YLAMINO)-2-METHYL-PROPIONITRILE
- 2-((4-CHLORO-6-(ETHYLAMINO)-s-TRIAZIN-2-YL)AMINO)-2-METHYLPROPIONITRILE
- Cyanazine
- DW3418
- FORTROL
- PAYZE
- PROPANENITRILE, 2-((4-CHLORO-6-(ETHYLAMINO)-1,3,5-TRIAZIN-2-YL)AMINO)-2-METHYL-
- PROPIONITRILE, 2-((4-CHLORO-6-(ETHYLAMINO)-s-TRIAZIN-2-YLAMINO)-2-METHYL-
- SD 15418
- s-TRIAZINE, 2-CHLORO-4-ETHYLAMINO-6-(1-CYANO-1-METHYL)ETHYLAMINO-
- WL 19805