Nitrapyrin (CASRN 1929-82-4)
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0176
Nitrapyrin; CASRN 1929-82-4
Health assessment information on a chemical substance is
included in IRIS only after a comprehensive review of chronic toxicity
data by U.S. EPA health scientists from several Program Offices and the
Office of Research and Development. The summaries presented in Sections
I and II represent a consensus reached in the review process. Background
information and explanations of the methods used to derive the values
given in IRIS are provided in the Background Documents.
STATUS OF DATA FOR Nitrapyrin
File First On-Line 03/31/1987
Category (section) |
Status |
Last Revised |
---|---|---|
Oral RfD Assessment (I.A.) | withdrawn | 03/01/1996 |
Inhalation RfC Assessment (I.B.) | no data | |
Carcinogenicity Assessment (II.) | no data |
_I. Chronic Health Hazard Assessments for Noncarcinogenic Effects
_I.A. Reference Dose for Chronic Oral Exposure (RfD)
Substance Name — Nitrapyrin
CASRN — 1929-82-4
The Oral RfD for nitrapyrin has been withdrawn on 07/01/1992 as a result of further review. A new RfD summary is in preparation by the RfD/RfC Work Group.
Agency Work Group Review — 09/29/1986, 05/27/1991
EPA Contacts:
Please contact the IRIS Hotline for all questions concerning this assessment or IRIS, in general, at (202)566-1676 (phone), (202)566-1749 (FAX) or hotline.iris@epa.gov (internet address).
Screening-Level Literature Review Findings — A screening-level review conducted by an EPA contractor of the more recent toxicology literature pertinent to the RfD for nitrapyrin conducted in August 2003 identified one or more significant new studies. IRIS users may request the references for those studies from the IRIS Hotline at hotline.iris@epa.gov or 202-566-1676.
_I.B. Reference Concentration for Chronic Inhalation Exposure (RfC)
Substance Name — Nitrapyrin
CASRN — 1929-82-4
Not available at this time.
_II. Carcinogenicity Assessment for Lifetime Exposure
Substance Name — Nitrapyrin
CASRN — 1929-82-4
This substance/agent has not undergone a complete evaluation and determination under US EPA's IRIS program for evidence of human carcinogenic potential.
_III.
[reserved]
_IV. [reserved]
_V. [reserved]
_VI. Bibliography
Substance Name — Nitrapyrin
CASRN — 1929-82-4
Not available at this time.
_VII. Revision History
Substance Name — Nitrapyrin
CASRN — 1929-82-4
Date |
Section |
Description |
---|---|---|
03/01/1991 | I.A.4. | Citations added |
03/01/1991 | VI. | Bibliography on-line |
01/01/1992 | IV. | Regulatory actions updated |
07/01/1992 | I.A. | Withdrawn; new RfD verified (in preparation) |
07/01/1992 | VI.A. | Oral RfD references withdrawn |
08/01/1995 | I.A., VI.A. | EPA's RfD/RfC and CRAVE workgroups were discontinued in May, 1995. Chemical substance reviews that were not completed by September 1995 were taken out of IRIS review. The IRIS Pilot Program replaced the workgroup functions beginning in September, 1995. |
03/01/1996 | I.A. | Contact changed |
04/01/1997 | III., IV., V. | Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information. |
10/28/2003 | I.A | Screening-Level Literature Review Findings message has been added. |
_VIII. Synonyms
Substance Name — Nitrapyrin
CASRN — 1929-82-4
Last Revised — 03/31/1987
- 1929-82-4
- 2-CHLORO-6-(TRICHLOROMETHYL)PYRIDINE
- DOWCO-163
- Nitrapyrin
- N-SERVE
- PYRIDINE, 2-CHLORO-6-(TRICHLOROMETHYL)-