Map and DirectionsThe headquarters building of the U.S. Department of Health and Human Services is located at the foot of Capitol Hill at 200 Independence Avenue S.W., Washington, D.C., 20201. HHS headquarters is served by Metrorail and Metrobus (Disclaimer). The closest Metrorail station is the Federal Center SW station, which is served by the Blue and Orange lines. 
Hubert H. Humphrey Building Address 200 Independence Avenue S.W. Washington, D.C. 20201 Driving Directions to the Hubert H. Humphrey Building From Northern Virginia and Points South: - Take I-395 North toward Washington
- Slight left at US-1 N (signs for Downtown/US-1 N)
- Turn right on Independence Avenue SW
- Arrive at 200 Independence Avenue SW
From Northern Virginia and Points West: - Take the George Washington Memorial Pkwy S/GW Pkwy S toward Washington
- Take the exit onto I-395 N/US-1 N toward Washington
- Turn right on Independence Avenue SW
- Arrive at 200 Independence Avenue SW
From Washington, DC and Points East: - Take Pennsylvania Avenue NW toward the Woodrow Wilson Plaza
- Turn Right on 3rd Street NW
- Turn Left on Independence Avenue SW
- Arrive at 200 Independence Ave SW
From Maryland and Points North: - Take I-95 South towards Washington
- Take I-495 South
- Take the Baltimore-Washington Parkway Exit towards Washington, Exit #22B
- Merge onto MD-295 South
- MD-295 South becomes DC-295 South
- Take the East Capitol Street exit
- East Capitol Street SE becomes E Capitol Street/Whitney M Young Memorial Bridge
- Continue on C Street NE
- Bear Left on North Carolina Avenue NE
- Bear Right on E Capitol Street NE
- Turn Left on 11th Street SE
- Turn Right on North Carolina Avenue SE
- Bear Right on Seward Square SE
- Bear Right on Pennsylvania Avenue SE
- Bear Left on a local road
- Continue on Independence Avenue SE to Independence Avenue SW
- Arrive at 200 Independence Avenue SW
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