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What You Need To Know About™ Multiple Myeloma
    Posted: 03/18/2005



Introduction






What Is Multiple Myeloma?






Risk Factors






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Staging






Treatment






Side Effects of Treatment







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Supportive Care

Infection
Anemia
Pain
Thinning Bones
Too Much Calcium in the Blood
Kidney Problems
Amyloidosis

Multiple myeloma and its treatment can lead to other health problems. You probably will receive supportive care to prevent or control these problems and to improve your comfort and quality of life.

This section tells about health problems that myeloma may cause and describes the supportive care people may need. Detailed information about supportive care is available on NCI's Web site at http://www.cancer.gov/cancertopics/coping and from NCI's Cancer Information Service at 1-800-4-CANCER.

Infection

People with multiple myeloma get infections very easily. You may receive antibiotics and other drugs to help protect you. Your health care team may advise you to stay away from crowds and from people with colds or other contagious diseases. If an infection develops, it can be serious and should be treated promptly. Some people need to stay in the hospital for treatment.

Anemia

Myeloma and its treatment can lead to anemia, which may make you feel very tired. Drugs or blood transfusions can help with this problem.

Pain

Multiple myeloma often causes bone pain. Your health care provider can suggest ways to relieve or reduce pain. For example, drugs and local radiation therapy can help control bone pain. A brace may relieve pain in the neck or back. Some people get pain relief from massage or acupuncture when used along with other approaches. Also, the patient may learn relaxation techniques such as listening to slow music or breathing slowly and comfortably. Sometimes surgery is needed if the spinal cord is compressed (squeezed).

The NCI offers booklets called Pain Control: A Guide for People with Cancer and Their Families, Get Relief from Cancer Pain, and Understanding Cancer Pain.

Thinning Bones

Myeloma cells keep new bone cells from forming, and bones become thin wherever there are myeloma cells. Your doctor may give you drugs to prevent bone thinning and help reduce the risk of fractures. Physical activity, such as walking, also helps keep bones strong.

Too Much Calcium in the Blood

Multiple myeloma may cause calcium to leave the bones and enter the bloodstream. If you have a very high level of calcium in your blood, you may lose your appetite. You also may feel nauseated, restless, or confused. A high calcium level can also make you very tired, weak, dehydrated, and thirsty. Drinking a lot of fluids and taking drugs that lower the calcium in the blood can be helpful.

Kidney Problems

Some patients with multiple myeloma have kidney problems. If the problems are severe, they may need dialysis. Dialysis removes wastes from the blood. In some cases, people with serious kidney problems may need a kidney transplant.

Amyloidosis

Some people with myeloma develop amyloidosis. Abnormal protein collects in tissues of the body. The build-up of protein can cause many problems, some of them severe. For example, protein can build up in the heart, causing chest pain and swollen feet. Drugs are used to treat amyloidosis.

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