The Deputy Commissioner for Patent Operations oversee all patent examining functions in the seven Patent Technology Centers. Patent Operations has more than 3500 highly skilled scientists and engineers.

Patent Operations provides administrative oversight to and coordinates the activities of Technology Centers 1600, 1700, 2100, 2600, 2800, 2900, 3600, and 3700

Technology Center 1600 provides examination for patent applications including Biotechnology and Organic fields.
 
Technology Center 1700 provides examination for patent applications including Chemical and Materials Engineering fields.
 
Technology Center 2100 provides examination for patent applications including Computer Architecture Software and Information Security.
 
Technology Center 2600 provides examination for patent applications including Communications.
 
Technology Center 2800 provides examination for patent applications including Semiconductors, Electrical and Optical Systems and Components.
 
Technology Center 2900 provides examination for patent applications including Designs.
 
Technology Center 3600 provides examination for patent applications including Transportation, Electronic Commerce, Construction, Agriculture, Licensing and Review.
 
Technology Center 3700 provides examination for patent applications including Mechanical Engineering, Manufacturing and Products.