Phylogenomics Program
The Phylogenomics Group at JGI is a scientific research group focusing on the development and use of methods in the emerging field of phylogenomics. Phylogenomics involves the integration of evolutionary reconstructions (e.g., phylogenetics) and genome sequence analysis. This approach allows both for a better understanding of the mechanisms of evolution as well as for improved interpretation of genome sequence data. We focus in particular on three aspects of phylogenomics:
- The development of computational methods that use phylogenetic trees as a tool in genome sequence analysis. Examples include the use of phylogenetic trees in the prediction of gene function and designing automated methods for phylogenetic classification of metagenomic sequence reads.
- The targeting of undersampled portions of the "Tree of Life" for genome sequencing. An example of this is the "Genomic Encyclopedia of Bacteria and Archaea" project. Third, we use phylogenomic methods to better understand how novelty (new functions) originates in organisms.
- Using phylogenomics to identify novel genes and pathways involved in carbon sequestration and energy production processes. Examples include carbon monoxide fixation, photosynthesis, and hydrogen production.
Members
