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Science News about Depression

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History of Childhood Abuse or Neglect Increases Risk of Major Depression
January 3, 2007 • Science Update
People who were abused or neglected as children have increased risk of major depression, which often begins in childhood and has lingering effects as they mature, according to a study funded by NIMH.
Landmark Council Session Spotlights “Real World” Trials
December 21, 2006 • Science Update
Principal investigators of NIMH's four large-scale clinical trials presented study results and their implications at the National Advisory Mental Health Council meeting on September 15, 2006.
Benefits to Employers Outweigh Enhanced Depression-Care Costs
December 4, 2006 • Press Release
It may be in society’s and employers’ best interests to offer programs that actively seek out and treat depression in the workforce, suggests an analysis funded by NIMH.
New NIMH Research Strives to Understand How Antidepressants May Be Associated with Suicidal Thoughts and Actions
November 13, 2006 • Science Update
The National Institute of Mental Health (NIMH), part of the National Institutes of Health, is funding five new research projects that will shed light on antidepressant medications, notably selective serotonin reuptake inhibitors (SSRIs), and their association with suicidal thoughts and actions.
Mouse Model May Reveal Anxiety Gene, Marker for Antidepressant Failure
November 9, 2006 • Science Update
Studies of a new mouse model suggest that a specific gene variation plays a role in the development of anxiety disorders and in resistance to common medications for anxiety and depression.
Odds of Beating Depression Diminish as Additional Treatment Strategies are Needed
November 1, 2006 • Science Update
An overall assessment of the nation's largest real-world study of treatment-resistant depression suggests that a patient with persistent depression can get well after trying several treatment strategies, but his or her odds of beating the depression diminish as additional treatment strategies are needed.
NIMH Researchers Discover Medication’s Antidepressant Potential
October 2, 2006 • Science Update
A commonly used sedative and motion-sickness treatment shows promise as a fast-acting antidepressant, according to a study conducted by researchers at NIMH.
Subsequent Treatment Strategies for Persistent Depression Yield Modest Results
September 1, 2006 • Science Update
Patients with treatment-resistant depression had a modest chance of becoming symptom-free when they tried different treatment strategies after two or three failed treatments, according to results from the nation's largest real-world study of depression.
Bipolar Disorder Exacts Twice Depression’s Toll in Workplace, Productivity Lags Even After Mood Lifts
September 1, 2006 • Press Release
Bipolar disorder costs twice as much in lost productivity as major depressive disorder, an NIMH funded study has found.
Experimental Medication Kicks Depression in Hours Instead of Weeks
August 7, 2006 • Press Release
People with treatment—resistant depression experienced symptom relief in as little as two hours with a single intravenous dose of ketamine, a medication usually used in higher doses as an anesthetic in humans and animals, in a preliminary study.
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