Academic Education
1997-2000 |
CalPoly State University, San Luis Obispo, CA
M.S. (Biological Sciences), Advisor: Dr. S. Elrod |
1988-1992 |
University of California, Santa Barbara, CA
B.A. (Biological Sciences) |
Research Interests and Experience
2000 – date, Developing DNA analysis software and designing laboratory microarray tests for the rapid and quantitative detection of microorganisms in complex environmental and medical samples.
Other Interests
- Wave Sliding
- Home Construction
- Offspring Generation
- Perl Programming Instruction
Professional Appointments
2007
- Present |
Software
Developer, Ecology Department, Earth Sciences Division,
Lawrence Berkeley National Laboratory, Berkeley, CA |
2003 – 2007 |
Principal Research Associate, Microbial Ecology & Environmental Engineering, Earth Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA |
2000-2003 |
Biomedical Scientist, Biology and Biotechnology Research Program, Biodefense Division, Lawrence Livermore Laboratory, Livermore, CA |
1997-1999 |
Graduate Research Assistant, Environmental Biotechnology Institute, San Luis Obispo, CA |
Peer-Reviewed Publications
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West, K.A., Johnson, D.R., Hu, P., DeSantis, T.Z.,
Brodie, E.L., Lee, P.K., Feil, H., Andersen, G.L., Zinder,
S.H. and Alvarez-Cohen, L. (2008) Comparative Genomics of Dehalococcoides
ethenogenes 195 and an Enrichment Culture Containing Unsequenced
Dehalococcoides Strains, Appl Environ Microbiol, 74,
3533-3540.
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DeSantis, T.Z., Brodie, E.L.,
Moberg, J.P., Zubieta, I.X., Piceno, Y.M. and
Andersen, G.L. (2007) High-density universal
16S rRNA microarray analysis reveals broader
diversity than typical clone library when sampling
the environment, Microb Ecol, 53, 371-383.
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Moissl, C., Osman, S., La Duc, M.T., Dekas, A., Brodie, E., DeSantis,
T.Z. and Venkateswaran, K. (2007) Molecular bacterial
community analysis of clean rooms where spacecraft are assembled, FEMS
Microbiol Ecol, 62, 131.
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Flanagan, J.L., Brodie, E.L., Weng, L., Lynch, S.V., Garcia,
O., Brown, R., Hugenholtz, P., DeSantis, T.Z.,
Andersen, G.L., Wiener-Kronish, J.P. and Bristow, J. (2007)
Loss of bacterial diversity during antibiotic treatment of
intubated patients colonized with Pseudomonas aeruginosa, J
Clin Microbiol, 45, 1954-1962.
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Dalevi, D., DeSantis, T.Z., Fredslund, J.,
Andersen, G.L., Markowitz, V.M. and Hugenholtz, P. (2007) Automated
group assignment in large phylogenetic trees using GRUNT: GRouping,
Ungrouping, Naming Tool, BMC Bioinformatics, 8,
402.
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Brodie, E.L., DeSantis, T.Z., Parker, J.P.,
Zubietta, I.X., Piceno, Y.M. and Andersen, G.L. (2007) Urban
aerosols harbor diverse and dynamic bacterial populations, Proc
Natl Acad Sci U S A, 104, 299-304.
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DeSantis, T.Z., Hugenholtz,
P., Larsen, N., Rojas, M., Brodie, E.L., Keller,
K., Huber, T., Dalevi, D., Hu, P. and Andersen,
G.L. (2006) Greengenes, a Chimera-Checked 16S
rRNA Gene Database and Workbench Compatible with
ARB, Appl
Environ Microbiol, 72, 5069-5072.
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DeSantis, T.Z., Hugenholtz, P., Keller,
K., Brodie, E.L., Larsen, N., Piceno, Y.M., Phan, R. and
Andersen, G.L. (2006) NAST: a multiple sequence alignment
server for comparative analysis of 16S rRNA genes, Nucleic
Acids Res, 34, W394-399.
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Lin, L.H., Wang, P.L., Rumble, D., Lippmann-Pipke, J., Boice,
E., Pratt, L.M., Sherwood Lollar, B., Brodie, E.L., Hazen,
T.C., Andersen, G.L., DeSantis, T.Z., Moser,
D.P., Kershaw, D. and Onstott, T.C. (2006) Long-term sustainability
of a high-energy, low-diversity crustal biome, Science, 314,
479-482.
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Brodie, E.L., DeSantis, T.Z., Joyner, D.C.,
Baek, S.M., Larsen, J.T., Andersen, G.L., Hazen, T.C., Richardson,
P.M., Herman, D.J., Tokunaga, T.K., Wan, J.M. and Firestone,
M.K. (2006) Application of a High-Density Oligonucleotide Microarray
Approach To Study Bacterial Population Dynamics during Uranium
Reduction and Reoxidation, Appl Environ Microbiol, 72,
6288-6298.
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DeSantis, T.Z., Stone, C.E.,
Murray, S.R., Moberg, J.P. and Andersen, G.L.
(2005) Rapid quantification and taxonomic classification
of environmental DNA from both prokaryotic and
eukaryotic origins using a microarray, FEMS
Microbiol Lett, 245, 271-278.
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DeSantis, T. Z., Dubosarskiy, I., Murray, S. R., and Andersen, G. L., (2003) Comprehensive aligned sequence construction for automated design of effective probes (CASCADE-P) using 16S rDNA. Bioinformatics 19: 1461-1468
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Wilson, K. H., Wilson, W. J., Radosevich, J. L., DeSantis, T. Z., Viswanathan, V. S., Kuczmarski, T. A., and Andersen, G. L. (2002) High density microarray of small subunit ribosomal DNA probes. Appl. Env. Micro. 68: (5) 2535-2541.
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Wilson, W. J., Strout, C. L., DeSantis, T. Z., Stilwell, J. L., Carrano, A. V., and Andersen, G. L. (2002) Sequence specific identification of 18 pathogenic microorganisms using microarray technology. Molecular and Cellular Probes 16: (2) 119-127.
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Radosevich, J. L., Wilson, W. J., Shinn, J. H., DeSantis, T. Z., and Andersen, G. L. (2002) Development of a high-volume aerosol collection system for the identification of airborne microorganisms. Letters in Applied Microbiology 34: (3) 162-167.
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Todd Z. DeSantis
Software
Developer
Ecology Department
Phone:
510-761-6720
Email: tdesantis@lbl.gov
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